| MeSH term | MeSH ID | Detail |
|---|---|---|
| Glioblastoma | D005909 | 27 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hypergammaglobulinemia | D006942 | 9 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Liver Cirrhosis, Experimental | D008106 | 36 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
2E,6E-farnesol
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
Cross Reference
Introduction
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2E,6E-farnesol?
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
PubChem Associated disorders and diseases
What pathways are associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2E,6E-farnesol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2E,6E-farnesol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2E,6E-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen CK et al. | The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity. | 2008 | J. Biol. Inorg. Chem. | pmid:18392864 |
| Gibbs JB et al. | Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. | 1993 | J. Biol. Chem. | pmid:8463291 |
| Kisselev O et al. | Efficient interaction with a receptor requires a specific type of prenyl group on the G protein gamma subunit. | 1995 | J. Biol. Chem. | pmid:7592699 |
| Fujiyama A et al. | S-farnesylation and methyl esterification of C-terminal domain of yeast RAS2 protein prior to fatty acid acylation. | 1991 | J. Biol. Chem. | pmid:1917931 |
| Maltese WA and Erdman RA | Characterization of isoprenoid involved in the post-translational modification of mammalian cell proteins. | 1989 | J. Biol. Chem. | pmid:2808372 |
| Gonzalez-Pacanowska D et al. | Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation. | 1988 | J. Biol. Chem. | pmid:3335546 |
| Bostedor RG et al. | Farnesol-derived dicarboxylic acids in the urine of animals treated with zaragozic acid A or with farnesol. | 1997 | J. Biol. Chem. | pmid:9083051 |
| Popják G et al. | Biosynthesis and structure of a new intermediate between farnesyl pyrophosphate and squalene. | 1969 | J. Biol. Chem. | pmid:4388617 |
| Carel K et al. | Insulin stimulates mitogen-activated protein kinase by a Ras-independent pathway in 3T3-L1 adipocytes. | 1996 | J. Biol. Chem. | pmid:8940037 |
| Anthony ML et al. | Inhibition of phosphatidylcholine biosynthesis following induction of apoptosis in HL-60 cells. | 1999 | J. Biol. Chem. | pmid:10391908 |
| Rosado JA and Sage SO | Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets. | 2001 | J. Biol. Chem. | pmid:11278479 |
| Wright MM et al. | Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis. | 2001 | J. Biol. Chem. | pmid:11306571 |
| Daily D et al. | Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by dual activation of the ras-phosphoinositide 3-kinase and jun n-terminal kinase pathways. | 2001 | J. Biol. Chem. | pmid:11290748 |
| Rilling HC | A new intermediate in the biosynthesis of squalene. | 1966 | J. Biol. Chem. | pmid:4287912 |
| Tschantz WR et al. | Lysosomal prenylcysteine lyase is a FAD-dependent thioether oxidase. | 2001 | J. Biol. Chem. | pmid:11078725 |
| Kisselev OG et al. | A farnesylated domain in the G protein gamma subunit is a specific determinant of receptor coupling. | 1994 | J. Biol. Chem. | pmid:8063769 |
| Lübben M and Morand K | Novel prenylated hemes as cofactors of cytochrome oxidases. Archaea have modified hemes A and O. | 1994 | J. Biol. Chem. | pmid:8063781 |
| Correll CC et al. | Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1994 | J. Biol. Chem. | pmid:8021239 |
| Cox AD et al. | The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation. | 1994 | J. Biol. Chem. | pmid:8034681 |
| Hartman HL et al. | Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium. | 2004 | J. Biol. Chem. | pmid:15131129 |