| MeSH term | MeSH ID | Detail |
|---|---|---|
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Meningioma | D008579 | 11 associated lipids |
| Neoplasms, Glandular and Epithelial | D009375 | 12 associated lipids |
| Neoplasms, Hormone-Dependent | D009376 | 23 associated lipids |
| Nephritis | D009393 | 19 associated lipids |
| Neuralgia | D009437 | 28 associated lipids |
| Neurilemmoma | D009442 | 10 associated lipids |
| Neuritis, Autoimmune, Experimental | D009444 | 4 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
2E,6E-farnesol
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
Cross Reference
Introduction
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2E,6E-farnesol?
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
PubChem Associated disorders and diseases
What pathways are associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2E,6E-farnesol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2E,6E-farnesol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2E,6E-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Prashad M et al. | N-(arylalkyl)farnesylamines: new potent squalene synthetase inhibitors. | 1993 | J. Med. Chem. | pmid:8496919 |
| Baker FC et al. | Farnesol and farnesal dehydrogenase(s) in corpora allata of the tobacco hornworm moth, Manduca sexta. | 1983 | J. Lipid Res. | pmid:6366103 |
| Sofer SS and Rilling HC | Mechanism of squalene biosynthesis: evidence against the involvement of free nerolidyl pyrophosphate. | 1969 | J. Lipid Res. | pmid:4305712 |
| Slakey LL et al. | Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta. | 1973 | J. Lipid Res. | pmid:4351784 |
| Aboushadi N and Krisans SK | Analysis of isoprenoid biosynthesis in peroxisomal-deficient Pex2 CHO cell lines. | 1998 | J. Lipid Res. | pmid:9741690 |
| Hanley K et al. | Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D. | 2001 | J. Lipid Res. | pmid:11254751 |
| Hiyoshi H et al. | Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes. | 2003 | J. Lipid Res. | pmid:12518031 |
| Matsuzawa T et al. | EFdA, a reverse transcriptase inhibitor, potently blocks HIV-1 ex vivo infection of Langerhans cells within epithelium. | 2014 | J. Invest. Dermatol. | pmid:24384694 |
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| Halaschek-Wiener J et al. | Farnesyl thiosalicylic acid chemosensitizes human melanoma in vivo. | 2003 | J. Invest. Dermatol. | pmid:12535206 |
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| Krishnakumaran A and Schneiderman HA | Prothoracotrophic activity of compounds that mimic juvenile hormone. | 1965 | J. Insect Physiol. | pmid:5848789 |
| Schneiderman HA et al. | Juvenile hormone activity of structurally unrelated compounds. | 1965 | J. Insect Physiol. | pmid:5848792 |
| Lanzrein B | Influence of a juvenile hormone analogue on vitellogenin synthesis and oögenesis in larvae of Nauphoeta cinerea. | 1974 | J. Insect Physiol. | pmid:4413859 |
| Roullet JB et al. | Inhibition of Ca2+ uptake into A7r5 vascular smooth muscle cells by farnesol: lack of effect on membrane fluidity and Ca2+-ATPase activities. | 1997 | J. Hypertens. | pmid:9488229 |
| Reif S et al. | The Ras antagonist, farnesylthiosalicylic acid (FTS), inhibits experimentally-induced liver cirrhosis in rats. | 1999 | J. Hepatol. | pmid:10604579 |
| Reif S et al. | Treatment of thioacetamide-induced liver cirrhosis by the Ras antagonist, farnesylthiosalicylic acid. | 2004 | J. Hepatol. | pmid:15288472 |
| Lin HP et al. | Localization of isoprenylated antigen of hepatitis delta virus by anti-farnesyl antibodies. | 1999 | J. Gen. Virol. | pmid:9934689 |