2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Mammary Neoplasms, Experimental D008325 67 associated lipids
Meningioma D008579 11 associated lipids
Neoplasms, Glandular and Epithelial D009375 12 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Nephritis D009393 19 associated lipids
Neuralgia D009437 28 associated lipids
Neurilemmoma D009442 10 associated lipids
Neuritis, Autoimmune, Experimental D009444 4 associated lipids
Neuroblastoma D009447 66 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

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Authors Title Published Journal PubMed Link
Mashiach-Farkash E et al. Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton. 2012 Oncotarget pmid:22776759
András IE et al. Lipid rafts and functional caveolae regulate HIV-induced amyloid beta accumulation in brain endothelial cells. 2012 Biochem. Biophys. Res. Commun. pmid:22490665
Mor A et al. Celecoxib enhances the anti-inflammatory effects of farnesylthiosalicylic acid on T cells independent of prostaglandin E(2) production. 2012 Inflammation pmid:22688643
Lichtor PA and Miller SJ Combinatorial evolution of site- and enantioselective catalysts for polyene epoxidation. 2012 Nat Chem pmid:23174978
Jamalian A et al. Chemical composition and antifungal activity of Matricaria recutita flower essential oil against medically important dermatophytes and soil-borne pathogens. 2012 J Mycol Med pmid:23518164
Shin KO et al. Terpene alcohols inhibit de novo sphingolipid biosynthesis. 2012 Planta Med. pmid:22274813
Wartenberg D et al. Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin. 2012 J Proteomics pmid:22634043
Yu LH et al. Possible inhibitory molecular mechanism of farnesol on the development of fluconazole resistance in Candida albicans biofilm. 2012 Antimicrob. Agents Chemother. pmid:22106223
Deveau A and Hogan DA Linking quorum sensing regulation and biofilm formation by Candida albicans. 2011 Methods Mol. Biol. pmid:21031315
de Castro Pimentel Figueiredo B et al. The Aspergillus nidulans nucA(EndoG) homologue is not involved in cell death. 2011 Eukaryotic Cell pmid:21131437
Gomes F et al. Farnesol as antibiotics adjuvant in Staphylococcus epidermidis control in vitro. 2011 Am. J. Med. Sci. pmid:21107231
Mor A et al. Inhibitory effect of farnesylthiosalicylic acid on mediators release by mast cells: preferential inhibition of prostaglandin D(2) and tumor necrosis factor-α release. 2011 Inflammation pmid:20706780
Madhani HD Quorum sensing in fungi: Q&A. 2011 PLoS Pathog. pmid:22046125
Gomes F et al. Effect of farnesol on structure and composition of Staphylococcus epidermidis biofilm matrix. 2011 Curr. Microbiol. pmid:21800262
Pammi M et al. Farnesol decreases biofilms of Staphylococcus epidermidis and exhibits synergy with nafcillin and vancomycin. 2011 Pediatr. Res. pmid:21857375
Teodoro JS et al. Hepatic FXR: key regulator of whole-body energy metabolism. 2011 Trends Endocrinol. Metab. pmid:21862343
Goto T et al. Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21862726
Fitzpatrick AH et al. Roles for farnesol and ABA in Arabidopsis flower development. 2011 Plant Signal Behav pmid:21758018
Mor A et al. Ras inhibition induces insulin sensitivity and glucose uptake. 2011 PLoS ONE pmid:21738773
Sharma M and Prasad R The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans. 2011 Antimicrob. Agents Chemother. pmid:21768514