| MeSH term | MeSH ID | Detail |
|---|---|---|
| Meningioma | D008579 | 11 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Liver Cirrhosis, Experimental | D008106 | 36 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Hypergammaglobulinemia | D006942 | 9 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
2E,6E-farnesol
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
Cross Reference
Introduction
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2E,6E-farnesol?
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
PubChem Associated disorders and diseases
What pathways are associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2E,6E-farnesol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2E,6E-farnesol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2E,6E-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Canonica L et al. | Biosynthesis of mycophenolic acid. | 1972 | J. Chem. Soc. Perkin Trans. I | pmid:4674609 |
| Akisue G | [Secretion of Myroxylon peruiforum L.f. 3. Physical and chemical characterization of essential oil from balsam and qualitative analysis of various componets]. | 1972 Jul-Dec | Rev Farm Bioquim Univ Sao Paulo | pmid:4664898 |
| Richards JB and Hemming FW | Dolichols, ubiquinones, geranylgeraniol and farnesol as the major metabolites of mevalonate in Phytophthora cactorum. | 1972 | Biochem. J. | pmid:4643705 |
| Madhavan K et al. | Farnesol metabolism in Drosophila melanogaster: ontogeny and tissue distribution of octanol dehydrogenase and aldehyde oxidase. | 1973 | J. Insect Physiol. | pmid:4631837 |
| Brockmann H and Knobloch G | [A new bacteriochlorophyll from Rhodospirillum rubrum]. | 1972 | Arch Mikrobiol | pmid:4627398 |
| Smith PM et al. | Proceedings: A double blind trial of carbenoxolone and geranyl farnesylacetate in gastric ulcer. | 1974 | Gut | pmid:4611753 |
| Keenan MV and Allen CM | Characterization of undecaprenyl pyrophosphate synthetase from Lactobacillus plantarum. | 1974 | Arch. Biochem. Biophys. | pmid:4599964 |
| Newman CR and Montgomery DA | A double-blind trial of oral gefarnate in duodenal ulcer. | 1973 | Br J Clin Pract | pmid:4580209 |
| Langman MJ et al. | Treatment of chronic gastric ulcer with carbenoxolone and gefarnate: a comparative trial. | 1973 | Br Med J | pmid:4577839 |
| Levinson HZ | [The evolution and biosynthesis of the terpinoid pheromones and hormones]. | 1972 | Naturwissenschaften | pmid:4571813 |
| Overton KH and Roberts FM | Biosynthesis of trans, trans- and cis, trans-farnesols by soluble enzymes from tissue cultures of Andrographis paniculata. | 1974 | Biochem. J. | pmid:4468823 |
| Tobe SS and Pratt GE | The influence of substrate concentrations on the rate of insect juvenile hormone biosynthesis by corpora allata of the desert locust in vitro. | 1974 | Biochem. J. | pmid:4462567 |
| Morozova NP et al. | [The effect of a controlled gas atmosphere on farnesene dynamics and the development of sunburn in apples]. | 1974 Jul-Aug | Prikl. Biokhim. Mikrobiol. | pmid:4453546 |
| Shechter I | Phosphate transfer from trans-farnesyl triphosphate to AMP in Gibberella fujikuroi. | 1974 | Biochim. Biophys. Acta | pmid:4423368 |
| Imai K et al. | Letter: Derivation of (plus)- and (minus)-C17-juvenile hormone from its racemic alcohol derivative via fungal metabolism. | 1974 | J. Am. Chem. Soc. | pmid:4414179 |
| Lanzrein B | Influence of a juvenile hormone analogue on vitellogenin synthesis and oögenesis in larvae of Nauphoeta cinerea. | 1974 | J. Insect Physiol. | pmid:4413859 |
| Binet L et al. | [Farnesol, psychosedative and spasmolytic drug]. | 1972 Sep-Oct | Therapie | pmid:4405589 |
| Beedle AS et al. | The stereochemistry of the reduction of mevaldic acid-coenzyme A hemithioacetal by rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1972 | FEBS Lett. | pmid:4405222 |
| Qureshi AA et al. | Lycopersene and prelycopersene pyrophosphate. Intermediates in carotene biosynthesis. | 1972 | J. Biol. Chem. | pmid:4403969 |
| Walton MJ and Pennock JF | Some studies on the biosynthesis of ubiguinone, isoprenoid alcohols, squalene and sterols by marine invertebrates. | 1972 | Biochem. J. | pmid:4403925 |
| Dugan RE and Porter JW | Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction. | 1972 | Arch. Biochem. Biophys. | pmid:4403691 |
| Beedle AS et al. | The stereochemistry of hydrogen transfer from NADPH catalysed by 3-hydroxy-3-methylglutaryl-coenzyme A reductase from rat liver. | 1972 | Eur. J. Biochem. | pmid:4403574 |
| Metzler M et al. | On the biosynthesis of juvenile hormone in the adult Cecropia moth. | 1971 | Z. Naturforsch. B | pmid:4401880 |
| Rilling HC | The effect of sterol carrier protein on squalene synthesis. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4400440 |
| Edmond J et al. | Presqualene alcohol. Further evidence on the structure of a C 30 precursor of squalene. | 1971 | J. Biol. Chem. | pmid:4399596 |
| Hintze-Podufal C | The juvenile hormone-like effect of farnesol derivatives on the pupal development of Cerura vinula L. | 1971 | Z. Naturforsch. B | pmid:4396584 |
| Popják G et al. | Biosynthesis and structure of a new intermediate between farnesyl pyrophosphate and squalene. | 1969 | J. Biol. Chem. | pmid:4388617 |
| Etemadi AH et al. | Assay of the possible organization of particle-bound enzymes with squalene synthetase and squalene oxidocyclase systems. | 1969 | Biochem. J. | pmid:4388240 |
| Nair KK | Susceptibility of mosquito larvae to a synthetic juvenile hormone, farnesyl diethylamine. | 1967 | Naturwissenschaften | pmid:4384815 |
| Graebe JE | Isoprenoid biosynthesis in a cell-free system from pea shoots. | 1967 | Science | pmid:4381746 |
| Krishna G et al. | Enzymic conversion of farnesyl pyrophosphate to squalene. | 1966 | Arch. Biochem. Biophys. | pmid:4380977 |
| Donninger C and Popják G | Studies on the biosynthesis of cholesterol. 18. The stereospecificity of mevaldate reductase and the biosynthesis of asymmetrically labelled farnesyl pyrophosphate. | 1966 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:4379290 |
| Samuel O et al. | Preparation of (1-3H) polyprenyl pyrophosphates. | 1974 | Biochimie | pmid:4375498 |
| Ellsworth RK and Nowak CA | A gas chromatographic-mass spectrometric analysis of the esterifying alcohols of pumpkin seed protochlorophylls. | 1974 | Anal. Biochem. | pmid:4362215 |
| Derksen A and Cohen P | Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro. | 1973 | J. Biol. Chem. | pmid:4355579 |
| Slakey LL et al. | Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta. | 1973 | J. Lipid Res. | pmid:4351784 |
| Beytia E et al. | Squalene synthetase. 3. Mechanism of the reaction. | 1973 | J. Biol. Chem. | pmid:4348553 |
| Qureshi AA et al. | Squalene synthetase. II. Purification and properties of bakers' yeast enzyme. | 1973 | J. Biol. Chem. | pmid:4348552 |
| Heintz R et al. | Plant sterol metabolism. Demonstration and identification of a biosynthetic intermediate between farnesyl PP and squalene in a higher plant. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4344813 |
| Qureshi AA et al. | Squalene synthetase. I. Dissociation and reassociation of enzyme complex. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4341049 |
| Warren CD and Jeanloz RW | Chemical synthesis of pyrophosphodiesters of carbohydrates and isoprenoid alcohols. Lipid intermediates of bacterial cell wall and antigenic polysaccharide biosynthesis. | 1972 | Biochemistry | pmid:4339875 |
| Stone KJ and Strominger JL | Inhibition of sterol biosynthesis by bacitracin. | 1972 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4338587 |
| Polito A et al. | Artificial substrates in squalene and sterol biosynthesis. | 1972 | J. Biol. Chem. | pmid:4337856 |
| Slakey LL et al. | The effects of fasting, refeeding, and time of day on the levels of enzymes effecting the conversion of -hydroxy- -methylglutaryl-coenzyme A to squalene. | 1972 | J. Biol. Chem. | pmid:4337504 |
| Kurokawa T et al. | Formation of polyprenyl phosphates by a cell-free enzyme of Micrococcus lysodeikticus. | 1971 | Biochem. Biophys. Res. Commun. | pmid:4334524 |
| George-Nascimento C et al. | Non enzymic formation of nerolidol from farnesyl pyrophosphate in the presence of bivalent cations. | 1971 | Biochem. Biophys. Res. Commun. | pmid:4334520 |
| Castelli A et al. | Effect of hydroxy analogs of coenzyme Q on DPNH- and succin-oxidase activities of yeast mitochondria. | 1971 | Biochem. Biophys. Res. Commun. | pmid:4324835 |
| Dialameh GH et al. | Enzymatic alkylation of menaquinone-o to menaquinones microsomes from chick liver. | 1970 | Biochim. Biophys. Acta | pmid:4323518 |
| Flint AP | The activity and kinetic properties of mevalonate kinase in superovulated rat ovary. | 1970 | Biochem. J. | pmid:4321929 |
| Gough DP and Hemming FW | The characterization and stereochemistry of biosynthesis of dolichols in rat liver. | 1970 | Biochem. J. | pmid:4319540 |
| Heinstein PF et al. | Biosynthesis of gossypol. Incorporation of mevalonate-2-14C and isoprenyl pyrophosphates. | 1970 | J. Biol. Chem. | pmid:4318479 |
| Epstein WW and Rilling HC | Studies on the mechanism of squalene biosynthesis. The structure of presqualene pyrophosphate. | 1970 | J. Biol. Chem. | pmid:4318477 |
| Christenson JG et al. | Enzymatic synthesis of the antigen carrier lipid. | 1969 | J. Biol. Chem. | pmid:4311788 |
| Popják G et al. | Artificial substrates for prenyltransferase. | 1969 | Biochem. J. | pmid:4309597 |
| Sofer SS and Rilling HC | Mechanism of squalene biosynthesis: evidence against the involvement of free nerolidyl pyrophosphate. | 1969 | J. Lipid Res. | pmid:4305712 |
| Popják G et al. | Synthesis of 10,11-dihydrofarnesyl pyrophosphate from 6,7-dihydrogeranyl pyrophosphate by prenyltransferase. | 1969 | Biochem. J. | pmid:4304159 |
| Dorsey JK and Porter JW | The inhibition of mevalonic kinase by geranyl and farnesyl pyrophosphates. | 1968 | J. Biol. Chem. | pmid:4300840 |
| Jungalwala FB and Porter JW | Biosynthesis of phytoene from isopentenyl and farnesyl pyrophosphates by a partially purified tomato enzyme system. | 1967 | Arch. Biochem. Biophys. | pmid:4293186 |
| Holloway PW and Popják G | The purification of 3,3-dimethylallyl- and geranyl-transferase and of isopentenyl pyrophosphate isomerase from pig liver. | 1967 | Biochem. J. | pmid:4292002 |
| Allen CM et al. | A long chain terpenyl pyrophosphate synthetase from Micrococcus lysodeikticus. | 1967 | J. Biol. Chem. | pmid:4290445 |
| Cornforth JW et al. | Studies on the biosynthesis of cholesterol. XX. Steric course of decarboxylation of 5-pyrophosphomevalonate and of the carbon to carbon bond formation in the biosynthesis of farnesyl pyrophosphate. | 1966 | J. Biol. Chem. | pmid:4288360 |
| Rilling HC | A new intermediate in the biosynthesis of squalene. | 1966 | J. Biol. Chem. | pmid:4287912 |
| Pastor Franco A | [Clinicobiological evolution of duodenal ulcer treated with gefarnate]. | 1966 | Rev Clin Esp | pmid:4286000 |
| Benedict CR et al. | Properties of farnesyl pyrophosphate synthetase of pig liver. | 1965 | Arch. Biochem. Biophys. | pmid:4284635 |
| Krishna G et al. | An enzyme-bound intermediate in the conversion of farnesyl pyrophosphate to squalene. | 1964 | Biochem. Biophys. Res. Commun. | pmid:4284347 |
| Sharma RN and Saxena KN | Orientation and developmental inhibition in the housefly by certain terpenoids. | 1974 | J. Med. Entomol. | pmid:4281838 |
| Muscio F et al. | Prequalene pyrophosphate. A normal intermediate in squalene biosynthesis. | 1974 | J. Biol. Chem. | pmid:4152099 |
| Qureshi AA et al. | Biosynthesis of prelycopersene pyrophosphate and lycopersene by squalene synthetase. | 1973 | J. Biol. Chem. | pmid:4144543 |
| Beedle AS et al. | Studies on the biosynthesis of tetrahymanol in Tetrahymena pyriformis. The mechanism of inhibition by cholesterol. | 1974 | Biochem. J. | pmid:4140721 |
| de Ropp JS and Troy FA | 2H NMR investigation of the organization and dynamics of polyisoprenols in membranes. | 1985 | J. Biol. Chem. | pmid:4066690 |
| Prestwich GD et al. | Experimental techniques for photoaffinity labeling of juvenile hormone binding proteins of insects with epoxyfarnesyl diazoacetate. | 1985 | Meth. Enzymol. | pmid:3929012 |
| Baba T et al. | Dehydrodolichyl diphosphate synthetase from rat seminiferous tubules. | 1987 | Arch. Biochem. Biophys. | pmid:3813545 |
| Maciejewska J | The influence of the Polish juvenoid Cyklopren on the development and survival of Xenopsylla cheopis (Rothschild, 1903) (Siphonaptera)--the principal vector of plague in man. | 1986 | Bull Inst Marit Trop Med Gdynia | pmid:3440169 |
| Gonzalez-Pacanowska D et al. | Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation. | 1988 | J. Biol. Chem. | pmid:3335546 |
| Ortiz de Montellano PR et al. | Substrate selectivity of squalene synthetase. | 1977 | Biochemistry | pmid:329862 |
| Ershova LS et al. | [Action of an analog of insect juvenile hormone farnesol ester on the flea Xenopsylla conformis Wagn]. | 1988 May-Jun | Med Parazitol (Mosk) | pmid:3173246 |
| Fioravanti CF and MacInnis AJ | The identification and characterization of a prenoid constituent (farnesol) of Hymenolepis diminuta (Cestoda). | 1977 | Comp. Biochem. Physiol., B | pmid:299634 |
| Rocha GR et al. | Effect of tt-farnesol and myricetin on in vitro biofilm formed by Streptococcus mutans and Candida albicans. | 2018 | BMC Complement Altern Med | pmid:29444673 |
| pmid:29380558 | ||||
| pmid:29181599 | ||||
| pmid:28684169 | ||||
| pmid:28622460 | ||||
| pmid:28603849 | ||||
| pmid:28584159 | ||||
| pmid:28471040 | ||||
| Cagliero C et al. | Analysis of essential oils and fragrances with a new generation of highly inert gas chromatographic columns coated with ionic liquids. | 2017 | J Chromatogr A | pmid:28343686 |
| Å piÄáková A et al. | Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions. | 2017 | Molecules | pmid:28338641 |
| pmid:28329720 | ||||
| Xia J et al. | In vitro inhibitory effects of farnesol and interactions between farnesol and antifungals against biofilms of Candida albicans resistant strains. | 2017 | Biofouling | pmid:28317391 |
| pmid:28285658 | ||||
| pmid:28284180 | ||||
| pmid:28192189 | ||||
| Wu L et al. | Farnesylthiosalicylic acid sensitizes hepatocarcinoma cells to artemisinin derivatives. | 2017 | PLoS ONE | pmid:28182780 |
| Schmukler E et al. | Continuous treatment with FTS confers resistance to apoptosis and affects autophagy. | 2017 | PLoS ONE | pmid:28151959 |
| Maltese WA and Erdman RA | Characterization of isoprenoid involved in the post-translational modification of mammalian cell proteins. | 1989 | J. Biol. Chem. | pmid:2808372 |
| pmid:28043124 | ||||
| pmid:27987234 | ||||
| Saito K et al. | An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens. | 2017 | Toxicol In Vitro | pmid:27965148 |
| Vandewaa EA et al. | Physiological role of HMG-CoA reductase in regulating egg production by Schistosoma mansoni. | 1989 | Am. J. Physiol. | pmid:2782464 |
| pmid:27796932 |