Jansen B et al. |
Farnesylthiosalicylic acid inhibits the growth of human Merkel cell carcinoma in SCID mice. |
1999 |
J. Mol. Med. |
pmid:10619439
|
Wang X et al. |
Waikialoid A suppresses hyphal morphogenesis and inhibits biofilm development in pathogenic Candida albicans. |
2012 |
J. Nat. Prod. |
pmid:22400916
|
Villegas LF et al. |
(+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids. |
2001 |
J. Nat. Prod. |
pmid:11678668
|
Jones TH et al. |
Farnesylamine from the ant Monomorium fieldi Forel. |
2003 |
J. Nat. Prod. |
pmid:12662086
|
Goodwin TE et al. |
African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol. |
2002 |
J. Nat. Prod. |
pmid:12350155
|
Goodwin TE et al. |
African elephant sesquiterpenes. |
1999 |
J. Nat. Prod. |
pmid:10579877
|
Li X et al. |
New polyoxygenated farnesylcyclohexenones, deacetoxyyanuthone A and its hydro derivative from the marine-derived fungus Penicillium sp. |
2003 |
J. Nat. Prod. |
pmid:14640527
|
Crick DC et al. |
Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells. |
1998 |
J. Neurochem. |
pmid:9603204
|
Chin PC et al. |
The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism. |
2004 |
J. Neurochem. |
pmid:15255937
|
Kafri M et al. |
Inhibition of Ras attenuates the course of experimental autoimmune neuritis. |
2005 |
J. Neuroimmunol. |
pmid:16154640
|
Aizman E et al. |
The combined treatment of Copaxone and Salirasib attenuates experimental autoimmune encephalomyelitis (EAE) in mice. |
2010 |
J. Neuroimmunol. |
pmid:20869125
|
Karussis D et al. |
The Ras-pathway inhibitor, S-trans-trans-farnesylthiosalicylic acid, suppresses experimental allergic encephalomyelitis. |
2001 |
J. Neuroimmunol. |
pmid:11694313
|
Kato N et al. |
Treatment of the chronic inflammation in peripheral target tissue improves the crushed nerve recovery in the rat: histopathological assessment of the nerve recovery. |
2002 |
J. Neurol. Sci. |
pmid:12220695
|
Ronderos DS et al. |
Farnesol-detecting olfactory neurons in Drosophila. |
2014 |
J. Neurosci. |
pmid:24623773
|
Bringmann A et al. |
Farnesol modulates membrane currents in human retinal glial cells. |
2000 |
J. Neurosci. Res. |
pmid:11054809
|
Marciano D et al. |
Neuroprotective effects of the Ras inhibitor S-trans-trans-farnesylthiosalicylic acid, measured by diffusion-weighted imaging after traumatic brain injury in rats. |
2007 |
J. Neurotrauma |
pmid:17711399
|
Rosales A et al. |
Synthesis of (±)-aureol by bioinspired rearrangements. |
2015 |
J. Org. Chem. |
pmid:25591135
|
Tsangarakis C et al. |
Zeolite NaY-promoted cyclization of farnesal: a short route to nanaimoal. |
2008 |
J. Org. Chem. |
pmid:18321121
|
Xie H et al. |
Synthesis and biological evaluation of the geometric farnesylated analogues of the a-factor mating peptide of Saccharomyces cerevisiae. |
2000 |
J. Org. Chem. |
pmid:11112575
|
Du Y and Wiemer DF |
Alpha-phosphono lactone analogues of farnesyl pyrophosphate: an asymmetric synthesis via ring-closing metathesis. |
2002 |
J. Org. Chem. |
pmid:12153272
|
Kubista B et al. |
Anticancer effects of zoledronic acid against human osteosarcoma cells. |
2006 |
J. Orthop. Res. |
pmid:16602111
|
Fioravanti CF and MacInnis AJ |
The in vitro effects of farnesol and derivatives on Hymenolepis diminuta. |
1976 |
J. Parasitol. |
pmid:978365
|
Wiseman DA et al. |
Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17138864
|
Huelin FE and Coggiola IM |
Superficial scald, a functional disorder of stored apples. IV. Effect of variety, maturity, oiled wraps and diphenylamine on the concentration of alpha-farnesene in the fruit. |
1968 |
J. Sci. Food Agric. |
pmid:5659583
|
Yue W et al. |
Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells. |
2007 Aug-Sep |
J. Steroid Biochem. Mol. Biol. |
pmid:17616457
|
Hasmim M et al. |
Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways. |
2007 |
J. Thromb. Haemost. |
pmid:17059425
|
Lazzerini PE et al. |
Rosuvastatin inhibits spontaneous and IL-1β-induced interleukin-6 production from human cultured osteoblastic cells. |
2013 |
Joint Bone Spine |
pmid:22999910
|
Khwaja A et al. |
The inhibition of human mesangial cell proliferation by S-trans, trans-farnesylthiosalicylic acid. |
2005 |
Kidney Int. |
pmid:16014024
|
Fong C et al. |
Monodisperse nonionic isoprenoid-type hexahydrofarnesyl ethylene oxide surfactants: high throughput lyotropic liquid crystalline phase determination. |
2011 |
Langmuir |
pmid:21294552
|
Henriques M et al. |
Effect of farnesol on Candida dubliniensis morphogenesis. |
2007 |
Lett. Appl. Microbiol. |
pmid:17257261
|
Satoh T et al. |
The effects of pravastatin, an HMG-CoA reductase inhibitor, on cell viability and DNA production of rat hepatocytes. |
1996 |
Life Sci. |
pmid:8831797
|
Chaudhary SC et al. |
Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: involvement of inflammation, Ras-ERK pathway and apoptosis. |
2009 |
Life Sci. |
pmid:19470390
|
Pratt GE and Tobe SS |
Juvenile hormones radiobiosynthesised by corpora allata of adult female locusts in vitro. |
1974 |
Life Sci. |
pmid:4823991
|
JarolÃm V et al. |
Natural and synthetic materials with insect hormones activity. 8. Juvenile activity of the farnesane-type compounds on Galleria mellonella. |
1969 |
Life Sci. |
pmid:5803377
|
NÄ•mec V et al. |
Natural and synthetic materials with insect hormone activity. 7. Juvenile activity of the farnesane-type compounds on Locusta migratoria L and Schistocerca gregaria (Forsk). |
1970 |
Life Sci. II |
pmid:5478093
|
Duncan RE and Archer MC |
Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes. |
2008 |
Lipids |
pmid:18509688
|
Hohl RJ et al. |
Stereochemistry-dependent inhibition of RAS farnesylation by farnesyl phosphonic acids. |
1998 |
Lipids |
pmid:9470172
|
Ownby SE and Hohl RJ |
Farnesol and geranylgeraniol: prevention and reversion of lovastatin-induced effects in NIH3T3 cells. |
2002 |
Lipids |
pmid:11908910
|
Ownby SE and Hohl RJ |
Isoprenoid alcohols restore protein isoprenylation in a time-dependent manner independent of protein synthesis. |
2003 |
Lipids |
pmid:14506838
|
Kothapalli R et al. |
Farnesylamine: an inhibitor of farnesylation and growth of ras-transformed cells. |
1993 |
Lipids |
pmid:8277827
|
Leonhardt I et al. |
The fungal quorum-sensing molecule farnesol activates innate immune cells but suppresses cellular adaptive immunity. |
2015 |
MBio |
pmid:25784697
|
Ershova LS et al. |
[Action of an analog of insect juvenile hormone farnesol ester on the flea Xenopsylla conformis Wagn]. |
1988 May-Jun |
Med Parazitol (Mosk) |
pmid:3173246
|
Tashiro M et al. |
Pravastatin inhibits farnesol production in Candida albicans and improves survival in a mouse model of systemic candidiasis. |
2012 |
Med. Mycol. |
pmid:21954955
|
Cordeiro RA et al. |
Minimum inhibitory concentrations of amphotericin B, azoles and caspofungin against Candida species are reduced by farnesol. |
2013 |
Med. Mycol. |
pmid:22712455
|
Sarazin A et al. |
In vitro pro- and anti-inflammatory responses to viable Candida albicans yeasts by a murine macrophage cell line. |
2010 |
Med. Mycol. |
pmid:20438293
|
Kim SY et al. |
Inhibition effect of new farnesol derivatives on all-trans-retinoic acid metabolism. |
2001 |
Metab. Clin. Exp. |
pmid:11699057
|
Wang C et al. |
Engineered heterologous FPP synthases-mediated Z,E-FPP synthesis in E. coli. |
2013 |
Metab. Eng. |
pmid:23608473
|
Prestwich GD et al. |
Experimental techniques for photoaffinity labeling of juvenile hormone binding proteins of insects with epoxyfarnesyl diazoacetate. |
1985 |
Meth. Enzymol. |
pmid:3929012
|
Rotblat B et al. |
The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer. |
2008 |
Meth. Enzymol. |
pmid:18374183
|
Berzat AC et al. |
Using inhibitors of prenylation to block localization and transforming activity. |
2006 |
Meth. Enzymol. |
pmid:16757354
|
Epand RM et al. |
Lipid-mediated a-factor interactions with artificial membranes. |
1995 |
Meth. Enzymol. |
pmid:7651149
|
Deveau A and Hogan DA |
Linking quorum sensing regulation and biofilm formation by Candida albicans. |
2011 |
Methods Mol. Biol. |
pmid:21031315
|
Andres DA et al. |
Rapid identification of cysteine-linked isoprenyl groups by metabolic labeling with [3H]farnesol and [3H]geranylgeraniol. |
1999 |
Methods Mol. Biol. |
pmid:10399149
|
Dudler T and Gelb MH |
Probing the role of H-Ras lipidation for signaling functions in Xenopus laevis oocytes. |
1999 |
Methods Mol. Biol. |
pmid:10399152
|
Corsini A et al. |
Incorporation of radiolabeled prenyl alcohols and their analogs into mammalian cell proteins. A useful tool for studying protein prenylation. |
1999 |
Methods Mol. Biol. |
pmid:10399150
|
Hisajima T et al. |
Protective effects of farnesol against oral candidiasis in mice. |
2008 |
Microbiol. Immunol. |
pmid:18667031
|
Abe S et al. |
Suppression of anti-Candida activity of macrophages by a quorum-sensing molecule, farnesol, through induction of oxidative stress. |
2009 |
Microbiol. Immunol. |
pmid:19493200
|
Cugini C et al. |
Candida albicans-produced farnesol stimulates Pseudomonas quinolone signal production in LasR-defective Pseudomonas aeruginosa strains. |
2010 |
Microbiology (Reading, Engl.) |
pmid:20656785
|
Machida K et al. |
Farnesol-induced growth inhibition in Saccharomyces cerevisiae by a cell cycle mechanism. |
1999 |
Microbiology (Reading, Engl.) |
pmid:10075411
|
Laffey SF and Butler G |
Phenotype switching affects biofilm formation by Candida parapsilosis. |
2005 |
Microbiology (Reading, Engl.) |
pmid:15817776
|
Cesco G |
[Geranyl farnesylacetate as a preventive and therapeutic agent in disorders of the digestive system caused by corticoids]. |
1967 Oct-Dec |
Minerva Gastroenterol |
pmid:5607545
|
Da Grada CT et al. |
[Endoscopic study of clinical trials of geranyl farnesylacetate]. |
1967 Oct-Dec |
Minerva Gastroenterol |
pmid:5607546
|
Ortone G and Furno F |
[Gefarnate in the therapy of peptic ulcer]. |
1968 |
Minerva Med. |
pmid:5707471
|
Gouveia V et al. |
Di- and sesquiterpenoids from Cystoseira genus: structure, intra-molecular transformations and biological activity. |
2013 |
Mini Rev Med Chem |
pmid:23621654
|
Charron G et al. |
Alkynyl-farnesol reporters for detection of protein S-prenylation in cells. |
2011 |
Mol Biosyst |
pmid:21107478
|
Kloog Y and Cox AD |
RAS inhibitors: potential for cancer therapeutics. |
2000 |
Mol Med Today |
pmid:11006529
|
Foster JM et al. |
Biosynthesis of isoprenoid compounds in Schistosoma mansoni. |
1993 |
Mol. Biochem. Parasitol. |
pmid:8264731
|
Agassandian M et al. |
Calcium-calmodulin kinase I cooperatively regulates nucleocytoplasmic shuttling of CCTα by accessing a nuclear export signal. |
2012 |
Mol. Biol. Cell |
pmid:22621903
|
Charette N et al. |
Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition. |
2010 |
Mol. Cancer |
pmid:20860815
|
Levy R et al. |
Galectin-3 promotes chronic activation of K-Ras and differentiation block in malignant thyroid carcinomas. |
2010 |
Mol. Cancer Ther. |
pmid:20682656
|
Barkan B et al. |
Phenotypic reversion of invasive neurofibromin-deficient schwannoma by FTS: Ras inhibition reduces BMP4/Erk/Smad signaling. |
2011 |
Mol. Cancer Ther. |
pmid:21632464
|
Goldberg L et al. |
Salirasib (farnesyl thiosalicylic acid) for brain tumor treatment: a convection-enhanced drug delivery study in rats. |
2008 |
Mol. Cancer Ther. |
pmid:19001442
|
Zundelevich A et al. |
Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid). |
2007 |
Mol. Cancer Ther. |
pmid:17541036
|
Blum R et al. |
Suppression of survivin expression in glioblastoma cells by the Ras inhibitor farnesylthiosalicylic acid promotes caspase-dependent apoptosis. |
2006 |
Mol. Cancer Ther. |
pmid:16985068
|
Ura H et al. |
Selective cytotoxicity of farnesylamine to pancreatic carcinoma cells and Ki-ras-transformed fibroblasts. |
1998 |
Mol. Carcinog. |
pmid:9496909
|
Stärkel P et al. |
Ras inhibition in hepatocarcinoma by S-trans-trans-farnesylthiosalicyclic acid: association of its tumor preventive effect with cell proliferation, cell cycle events, and angiogenesis. |
2012 |
Mol. Carcinog. |
pmid:21882255
|
Léger T et al. |
The Metacaspase (Mca1p) Restricts O-glycosylation During Farnesol-induced Apoptosis in Candida albicans. |
2016 |
Mol. Cell Proteomics |
pmid:27125826
|
Léger T et al. |
The metacaspase (Mca1p) has a dual role in farnesol-induced apoptosis in Candida albicans. |
2015 |
Mol. Cell Proteomics |
pmid:25348831
|
Ferdinandy P et al. |
Rapid pacing-induced preconditioning is recaptured by farnesol treatment in hearts of cholesterol-fed rats: role of polyprenyl derivatives and nitric oxide. |
1998 |
Mol. Cell. Biochem. |
pmid:9774182
|
Cox AD et al. |
Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein. |
1992 |
Mol. Cell. Biol. |
pmid:1375323
|
Lagace TA et al. |
Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis. |
2002 |
Mol. Cell. Biol. |
pmid:12052891
|
McMahon LP et al. |
Farnesylthiosalicylic acid inhibits mammalian target of rapamycin (mTOR) activity both in cells and in vitro by promoting dissociation of the mTOR-raptor complex. |
2005 |
Mol. Endocrinol. |
pmid:15459249
|
Halaschek-Wiener J et al. |
A novel Ras antagonist regulates both oncogenic Ras and the tumor suppressor p53 in colon cancer cells. |
2000 |
Mol. Med. |
pmid:11055588
|
Funari SS et al. |
Farnesol and geranylgeraniol modulate the structural properties of phosphatidylethanolamine model membranes. |
2005 Jul-Aug |
Mol. Membr. Biol. |
pmid:16154902
|
Colabardini AC et al. |
Involvement of the Aspergillus nidulans protein kinase C with farnesol tolerance is related to the unfolded protein response. |
2010 |
Mol. Microbiol. |
pmid:21091509
|
Savoldi M et al. |
Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase. |
2008 |
Mol. Microbiol. |
pmid:18681941
|
Bai C et al. |
Characterization of a hyperactive Cyr1 mutant reveals new regulatory mechanisms for cellular cAMP levels in Candida albicans. |
2011 |
Mol. Microbiol. |
pmid:21992526
|
Davis-Hanna A et al. |
Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesis. |
2008 |
Mol. Microbiol. |
pmid:18078440
|
Hogan DA et al. |
A Pseudomonas aeruginosa quorum-sensing molecule influences Candida albicans morphology. |
2004 |
Mol. Microbiol. |
pmid:15554963
|
Cugini C et al. |
Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa. |
2007 |
Mol. Microbiol. |
pmid:17640272
|
Dichtl K et al. |
Farnesol misplaces tip-localized Rho proteins and inhibits cell wall integrity signalling in Aspergillus fumigatus. |
2010 |
Mol. Microbiol. |
pmid:20398212
|
Semighini CP et al. |
Farnesol-induced apoptosis in Aspergillus nidulans reveals a possible mechanism for antagonistic interactions between fungi. |
2006 |
Mol. Microbiol. |
pmid:16420349
|
Bandara HM et al. |
Incorporation of Farnesol Significantly Increases the Efficacy of Liposomal Ciprofloxacin against Pseudomonas aeruginosa Biofilms in Vitro. |
2016 |
Mol. Pharm. |
pmid:27383205
|
Zhang X et al. |
PEG-farnesyl thiosalicylic acid telodendrimer micelles as an improved formulation for targeted delivery of paclitaxel. |
2014 |
Mol. Pharm. |
pmid:24987803
|
Benford HL et al. |
Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs. |
1999 |
Mol. Pharmacol. |
pmid:10385693
|
Maher M et al. |
Activation of TRPA1 by farnesyl thiosalicylic acid. |
2008 |
Mol. Pharmacol. |
pmid:18171730
|
Rung E et al. |
Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa cells. |
2006 |
Mol. Reprod. Dev. |
pmid:16868926
|
Jin J et al. |
Farnesol, a potential efflux pump inhibitor in Mycobacterium smegmatis. |
2010 |
Molecules |
pmid:21042264
|
Å piÄáková A et al. |
Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions. |
2017 |
Molecules |
pmid:28338641
|
Togashi N et al. |
Effects of two terpene alcohols on the antibacterial activity and the mode of action of farnesol against Staphylococcus aureus. |
2008 |
Molecules |
pmid:19078849
|