MeSH term | MeSH ID | Detail |
---|---|---|
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Casey PJ et al. | p21ras is modified by a farnesyl isoprenoid. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2682646 |
Vandewaa EA et al. | Physiological role of HMG-CoA reductase in regulating egg production by Schistosoma mansoni. | 1989 | Am. J. Physiol. | pmid:2782464 |
Ershova LS et al. | [Action of an analog of insect juvenile hormone farnesol ester on the flea Xenopsylla conformis Wagn]. | 1988 May-Jun | Med Parazitol (Mosk) | pmid:3173246 |
Gonzalez-Pacanowska D et al. | Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation. | 1988 | J. Biol. Chem. | pmid:3335546 |
Baba T et al. | Dehydrodolichyl diphosphate synthetase from rat seminiferous tubules. | 1987 | Arch. Biochem. Biophys. | pmid:3813545 |
Maciejewska J | The influence of the Polish juvenoid Cyklopren on the development and survival of Xenopsylla cheopis (Rothschild, 1903) (Siphonaptera)--the principal vector of plague in man. | 1986 | Bull Inst Marit Trop Med Gdynia | pmid:3440169 |
Prestwich GD et al. | Experimental techniques for photoaffinity labeling of juvenile hormone binding proteins of insects with epoxyfarnesyl diazoacetate. | 1985 | Meth. Enzymol. | pmid:3929012 |
de Ropp JS and Troy FA | 2H NMR investigation of the organization and dynamics of polyisoprenols in membranes. | 1985 | J. Biol. Chem. | pmid:4066690 |
Wegner Z | Insecticidal action of "Cyklopren" against mosquitoes in minute artificial water containers. | 1984 | Bull Inst Marit Trop Med Gdynia | pmid:6545940 |
Koeppe JK et al. | A specific photoaffinity label for hemolymph and ovarian juvenile hormone-binding proteins in Leucophaea maderae. | 1984 | J. Biol. Chem. | pmid:6699014 |
Baker FC et al. | Farnesol and farnesal dehydrogenase(s) in corpora allata of the tobacco hornworm moth, Manduca sexta. | 1983 | J. Lipid Res. | pmid:6366103 |
Krzemińska A et al. | [Field studies on the effectiveness of insecticides containing juvenile hormones against the ant Monomorium pharaonis L]. | 1983 | Rocz Panstw Zakl Hig | pmid:6612185 |
Miyakawa T et al. | Role of metabolism of the mating pheromone in sexual differentiation of the heterobasidiomycete Rhodosporidium toruloides. | 1982 | J. Bacteriol. | pmid:7050081 |
Nishino T et al. | Enzymatic formation of nerolidol in cell-free extract of Rhodotorula glutinis. | 1982 | J. Biochem. | pmid:6891702 |
Saito Y and Ogura K | Biosynthesis of menaquinones. Enzymatic prenylation of 1,4-dihydroxy-2-naphthoate by Micrococcus luteus membrane fractions. | 1981 | J. Biochem. | pmid:7275947 |
Styczyńska B and Krzemińska A | [Laboratory testing of control of the Monomorium pharaonis L. ants with the use of juvenile hormones]. | 1981 | Rocz Panstw Zakl Hig | pmid:7313455 |
Saito A and Rilling HC | The formation of cyclic sesquiterpenes from farnesyl pyrophosphate by prenyltransferase. | 1981 | Arch. Biochem. Biophys. | pmid:7259201 |
Takahashi I and Ogura K | Farnesyl pyrophosphate synthetase from Bacillus subtilis. | 1981 | J. Biochem. | pmid:6792191 |
Kamiya Y et al. | Metabolites of mating pheromone, rhodotorucine A, by a cells of Rhodosporidium toruloides. | 1980 | Biochem. Biophys. Res. Commun. | pmid:7396935 |
Koyama T et al. | Substrate specificity of squalene synthetase. | 1980 | Biochim. Biophys. Acta | pmid:7357018 |
Styczyńska B et al. | [Biological activity of the Polish juvenile hormone cyclopren tested on various Diptera species]. | 1980 | Rocz Panstw Zakl Hig | pmid:7466235 |
Fukui S | [Sexual differentiation in heterobasidiomycetous yeasts (author's transl)]. | 1980 | Seikagaku | pmid:7019358 |
Keller RK et al. | Studies on the regulation of glycoprotein biosynthesis. An investigation of the rate-limiting steps of dolichyl phosphate biosynthesis. | 1979 | J. Biol. Chem. | pmid:489612 |
Andries JC | [Experimental induction of morphogenesis and degeneration of mesentery in Aeshna cyana (Insecta, Odonata)]. | 1979 | Gen. Comp. Endocrinol. | pmid:499746 |
Styczyńska B and Sereda B | [Effect of hormone-like substances on the gonads of domestic fly (Musca domestica L.)]. | 1979 | Rocz Panstw Zakl Hig | pmid:515638 |
Parker TS et al. | Inhibition of liver prenyltransferase by alkyl phosphonates and phosphonophosphates. | 1978 | Biochim. Biophys. Acta | pmid:687653 |
Gavey KL and Scallen TJ | Nonparticipation of 105,000 x g liver supernatant or sterol carrier protein in the enzymatic conversion of farnesyl pyrophosphate to squalene by rat liver microsomes. | 1978 | J. Biol. Chem. | pmid:209043 |
Bhavnani BR and Woolever CA | Formation of steroids by the pregnant mare. VI. Metabolism of [14C]farnesyl pyrophosphate and [3H]dehydroepiandrosterone injected into the fetus. | 1978 | Endocrinology | pmid:155006 |
Cantwell SG et al. | Biodegradation of acyclic isoprenoids by Pseudomonas species. | 1978 | J. Bacteriol. | pmid:681275 |
Kamiya Y et al. | Structure of rhodotorucine A, a novel lipopeptide, inducing mating tube formation in Rhodosporidium toruloides. | 1978 | Biochem. Biophys. Res. Commun. | pmid:708426 |
Baba T and Allen CM | Substrate specificity of undecaprenyl pyrophosphate synthetase from Lactobacillus plantarum. | 1978 | Biochemistry | pmid:728420 |
Tsuchiya E and Fukui S | Binding of rhodotorucine A, a lipopeptidyl mating hormone, to a cells of Rhodosporidium toruloides for induction of sexual differentiation. | 1978 | Biochem. Biophys. Res. Commun. | pmid:743290 |
Agnew WS and Popják G | Squalene synthetase. Stoichiometry and kinetics of presqualene pyrophosphate and squalene synthesis by yeast microsomes. | 1978 | J. Biol. Chem. | pmid:26684 |
Bertolino A et al. | Polyisoprenoid amphiphilic compounds as inhibitors of squalene synthesis and other microsomal enzymes. | 1978 | Biochim. Biophys. Acta | pmid:210830 |
Cornforth J | Symmetry of squalene epoxidation in vivo. | 1977 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:22855 |
de Montellano PR et al. | Inhibition of squalene synthetase by farnesyl pyrophosphate analogues. | 1977 | J. Med. Chem. | pmid:189031 |
Mackie H and Overton KH | Hydrolysis and isomerization of trans,trans-farnesyl diphosphate by Andrographis tissue-culture enzymes. | 1977 | Eur. J. Biochem. | pmid:198206 |
Ortiz de Montellano PR et al. | Substrate selectivity of squalene synthetase. | 1977 | Biochemistry | pmid:329862 |
Fioravanti CF and MacInnis AJ | The identification and characterization of a prenoid constituent (farnesol) of Hymenolepis diminuta (Cestoda). | 1977 | Comp. Biochem. Physiol., B | pmid:299634 |
Peter MG et al. | [On the incorporation of geraniol and farnesol into cantharidin (author's transl)]. | 1977 | Helv. Chim. Acta | pmid:558966 |
L'Hélias C | [Study on deshydrogenases implicated in control of farnesol and juvenile hormone metabolisms in Pieris brassicae (author's transl)]. | 1977 | Ann. Endocrinol. (Paris) | pmid:612274 |
Peter MG et al. | [Identification of farnesol as an intermediate in the biosynthesis of cantharidin from mevalonolactone]. | 1977 | Helv. Chim. Acta | pmid:599044 |
Micciarelli AS | Effects of farnesyl methyl ether on embryos of Schistocerca Gregaria (Orthoptera). | 1977 | Acta Embryol Exp (Palermo) | pmid:605750 |
Boisvenue RJ et al. | Haemonchus contortus: effects of compounds with juvenile hormone activity on the in vitro development of infective larvae. | 1977 | Exp. Parasitol. | pmid:862711 |
Peter MG et al. | [Incorporation experiments with (3H and 14C) doubly labelled farnesols into cantharidin (author's transl)]. | 1977 | Helv. Chim. Acta | pmid:893117 |
Styczyńska B et al. | [2,3-methylenefarnesenic acid derivatives as juvenile hormone analogs against housefly (Musca domestica L.)]. | 1977 | Wiad Parazytol | pmid:899003 |
King HL and Rilling HC | Avian liver prenyltransferase. The role of metal in substrate binding and the orientation of substrates during catalysis. | 1977 | Biochemistry | pmid:901755 |
Ledoux A | [Effect of a farnesol derivative on the appearance of winged females in aphaenogaster senilis (Hymenoptera, Formicoidea)]. | 1976 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:817818 |
Hanson JR and Nyfeler R | Studies in terpenoid biosynthesis. Part 18. Biosynthesis of culmorin. | 1976 | J. Chem. Soc. Perkin Trans. I | pmid:1034641 |
Ortiz de Montellano PR et al. | Letter: Squalene synthetase. Differentiation between the two substrate binding sites by a substrate analogue. | 1976 | J. Am. Chem. Soc. | pmid:1254859 |