MeSH term | MeSH ID | Detail |
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Anisakiasis | D017129 | 2 associated lipids |
Candidiasis, Invasive | D058365 | 2 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Deveau A and Hogan DA | Linking quorum sensing regulation and biofilm formation by Candida albicans. | 2011 | Methods Mol. Biol. | pmid:21031315 |
Mann FM et al. | Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis. | 2011 | FEBS Lett. | pmid:21237161 |
de Castro Pimentel Figueiredo B et al. | The Aspergillus nidulans nucA(EndoG) homologue is not involved in cell death. | 2011 | Eukaryotic Cell | pmid:21131437 |
Gomes F et al. | Farnesol as antibiotics adjuvant in Staphylococcus epidermidis control in vitro. | 2011 | Am. J. Med. Sci. | pmid:21107231 |
Busch S and Unruh T | The influence of additives on the nanoscopic dynamics of the phospholipid dimyristoylphosphatidylcholine. | 2011 | Biochim. Biophys. Acta | pmid:21036141 |
Shareck J and Belhumeur P | Modulation of morphogenesis in Candida albicans by various small molecules. | 2011 | Eukaryotic Cell | pmid:21642508 |
Yang L et al. | ZL11n is a novel nitric oxide-releasing derivative of farnesylthiosalicylic acid that induces apoptosis in human hepatoma HepG2 cells via MAPK/mitochondrial pathways. | 2011 | Biochem. Biophys. Res. Commun. | pmid:21621522 |
Yoo S et al. | Antimicrobial traits of tea- and cranberry-derived polyphenols against Streptococcus mutans. | 2011 | Caries Res. | pmid:21720161 |
Cortés M et al. | Drimenol: A versatile synthon for compounds with trans-drimane skeleton. | 2011 | Nat Prod Commun | pmid:21560760 |
Borbath I and Stärkel P | Chemoprevention of hepatocellular carcinoma. Proof of concept in animal models. | 2011 | Acta Gastroenterol. Belg. | pmid:21563652 |
Zhang L et al. | Bisbibenzyls, a new type of antifungal agent, inhibit morphogenesis switch and biofilm formation through upregulation of DPP3 in Candida albicans. | 2011 | PLoS ONE | pmid:22174935 |
Hall RA et al. | The quorum-sensing molecules farnesol/homoserine lactone and dodecanol operate via distinct modes of action in Candida albicans. | 2011 | Eukaryotic Cell | pmid:21666074 |
Biran A et al. | Downregulation of survivin and aurora A by histone deacetylase and RAS inhibitors: a new drug combination for cancer therapy. | 2011 | Int. J. Cancer | pmid:20473860 |
Fong C et al. | Monodisperse nonionic isoprenoid-type hexahydrofarnesyl ethylene oxide surfactants: high throughput lyotropic liquid crystalline phase determination. | 2011 | Langmuir | pmid:21294552 |
Nagai H et al. | Development of a novel PPARγ ligand screening system using pinpoint fluorescence-probed protein. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21307572 |
Rahman NK et al. | Enzymatic synthesis of farnesyl laurate in organic solvent: initial water activity, kinetics mechanism, optimization of continuous operation using packed bed reactor and mass transfer studies. | 2011 | Bioprocess Biosyst Eng | pmid:21327986 |
Gori K et al. | Alcohol-based quorum sensing plays a role in adhesion and sliding motility of the yeast Debaryomyces hansenii. | 2011 | FEMS Yeast Res. | pmid:22093748 |
Madhani HD | Quorum sensing in fungi: Q&A. | 2011 | PLoS Pathog. | pmid:22046125 |
Gomes F et al. | Effect of farnesol on structure and composition of Staphylococcus epidermidis biofilm matrix. | 2011 | Curr. Microbiol. | pmid:21800262 |
Pammi M et al. | Farnesol decreases biofilms of Staphylococcus epidermidis and exhibits synergy with nafcillin and vancomycin. | 2011 | Pediatr. Res. | pmid:21857375 |
Teodoro JS et al. | Hepatic FXR: key regulator of whole-body energy metabolism. | 2011 | Trends Endocrinol. Metab. | pmid:21862343 |
Goto T et al. | Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways. | 2011 | Am. J. Physiol. Endocrinol. Metab. | pmid:21862726 |
Fitzpatrick AH et al. | Roles for farnesol and ABA in Arabidopsis flower development. | 2011 | Plant Signal Behav | pmid:21758018 |
Mor A et al. | Ras inhibition induces insulin sensitivity and glucose uptake. | 2011 | PLoS ONE | pmid:21738773 |
Sharma M and Prasad R | The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans. | 2011 | Antimicrob. Agents Chemother. | pmid:21768514 |
Nishimori R et al. | Biosynthesis of unnatural bacteriochlorophyll c derivatives esterified with α,ω-diols in the green sulfur photosynthetic bacterium Chlorobaculum tepidum. | 2011 | Biochemistry | pmid:21846125 |
Riely GJ et al. | A phase II trial of Salirasib in patients with lung adenocarcinomas with KRAS mutations. | 2011 | J Thorac Oncol | pmid:21847063 |
Ganguly S et al. | Zap1 control of cell-cell signaling in Candida albicans biofilms. | 2011 | Eukaryotic Cell | pmid:21890817 |
Dinamarco TM et al. | Farnesol-induced cell death in the filamentous fungus Aspergillus nidulans. | 2011 | Biochem. Soc. Trans. | pmid:21936849 |
Mor A et al. | Inhibition of contact sensitivity by farnesylthiosalicylic acid-amide, a potential Rap1 inhibitor. | 2011 | J. Invest. Dermatol. | pmid:21716322 |
Pando R et al. | The Ras antagonist farnesylthiosalicylic acid ameliorates experimental myocarditis in the rat. | 2010 Mar-Apr | Cardiovasc. Pathol. | pmid:19144546 |
Liu P et al. | Farnesol induces apoptosis and oxidative stress in the fungal pathogen Penicillium expansum. | 2010 Mar-Apr | Mycologia | pmid:20361499 |
Gilpin S and Maibach H | Allergic contact dermatitis caused by farnesol: clinical relevance. | 2010 | Cutan Ocul Toxicol | pmid:20858058 |
Charette N et al. | Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition. | 2010 | Mol. Cancer | pmid:20860815 |
Aizman E et al. | The combined treatment of Copaxone and Salirasib attenuates experimental autoimmune encephalomyelitis (EAE) in mice. | 2010 | J. Neuroimmunol. | pmid:20869125 |
Kubesová A et al. | Separation of attogram terpenes by the capillary zone electrophoresis with fluorometric detection. | 2010 | J Chromatogr A | pmid:20933239 |
Bhagatji P et al. | Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane. | 2010 | Biophys. J. | pmid:21081081 |
Tsimberidou AM et al. | Phase 1 first-in-human clinical study of S-trans,trans-farnesylthiosalicylic acid (salirasib) in patients with solid tumors. | 2010 | Cancer Chemother. Pharmacol. | pmid:19484470 |
Joo JH and Jetten AM | Molecular mechanisms involved in farnesol-induced apoptosis. | 2010 | Cancer Lett. | pmid:19520495 |
Sarazin A et al. | In vitro pro- and anti-inflammatory responses to viable Candida albicans yeasts by a murine macrophage cell line. | 2010 | Med. Mycol. | pmid:20438293 |
Lee J et al. | Proto-oncogenic H-Ras, K-Ras, and N-Ras are involved in muscle differentiation via phosphatidylinositol 3-kinase. | 2010 | Cell Res. | pmid:20603646 |
Shimomura K et al. | 2,3-Dihydrohomofarnesal: female sex attractant pheromone component of Callosobruchus rhodesianus (Pic). | 2010 | J. Chem. Ecol. | pmid:20607368 |
Gregus P et al. | Ultra high performance liquid chromatography tandem mass spectrometry analysis of quorum-sensing molecules of Candida albicans. | 2010 | J Pharm Biomed Anal | pmid:20580513 |
Ghosh S et al. | Candida albicans cell wall components and farnesol stimulate the expression of both inflammatory and regulatory cytokines in the murine RAW264.7 macrophage cell line. | 2010 | FEMS Immunol. Med. Microbiol. | pmid:20618847 |
Dinamarco TM et al. | The roles played by Aspergillus nidulans apoptosis-inducing factor (AIF)-like mitochondrial oxidoreductase (AifA) and NADH-ubiquinone oxidoreductases (NdeA-B and NdiA) in farnesol resistance. | 2010 | Fungal Genet. Biol. | pmid:20654725 |
Cugini C et al. | Candida albicans-produced farnesol stimulates Pseudomonas quinolone signal production in LasR-defective Pseudomonas aeruginosa strains. | 2010 | Microbiology (Reading, Engl.) | pmid:20656785 |
Weber K et al. | The quorum-sensing molecule E,E-farnesol--its variable secretion and its impact on the growth and metabolism of Candida species. | 2010 | Yeast | pmid:20641010 |
Bustinza-Linares E et al. | Salirasib in the treatment of pancreatic cancer. | 2010 | Future Oncol | pmid:20528225 |
Deveau A et al. | Farnesol induces hydrogen peroxide resistance in Candida albicans yeast by inhibiting the Ras-cyclic AMP signaling pathway. | 2010 | Eukaryotic Cell | pmid:20118211 |
Moya M et al. | Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile. | 2010 | Chem. Biol. Interact. | pmid:20079722 |