MeSH term | MeSH ID | Detail |
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Anisakiasis | D017129 | 2 associated lipids |
Candidiasis, Invasive | D058365 | 2 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Togashi N et al. | Effects of two terpene alcohols on the antibacterial activity and the mode of action of farnesol against Staphylococcus aureus. | 2008 | Molecules | pmid:19078849 |
Shchepin R et al. | Influence of heterocyclic and oxime-containing farnesol analogs on quorum sensing and pathogenicity in Candida albicans. | 2008 | Bioorg. Med. Chem. | pmid:18037299 |
Semighini CP et al. | Inhibition of Fusarium graminearum growth and development by farnesol. | 2008 | FEMS Microbiol. Lett. | pmid:18201191 |
Golczak M et al. | Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. | 2008 | J. Biol. Chem. | pmid:18195010 |
Maher M et al. | Activation of TRPA1 by farnesyl thiosalicylic acid. | 2008 | Mol. Pharmacol. | pmid:18171730 |
Shimomura K et al. | Homofarnesals: female sex attractant pheromone components of the southern cowpea weevil, Callosobruchus chinensis. | 2008 | J. Chem. Ecol. | pmid:18351422 |
Weber K et al. | Secretion of E,E-farnesol and biofilm formation in eight different Candida species. | 2008 | Antimicrob. Agents Chemother. | pmid:18332168 |
Teshima K and Kondo T | Analytical method for determination of allylic isoprenols in rat tissues by liquid chromatography/tandem mass spectrometry following chemical derivatization with 3-nitrophtalic anhydride. | 2008 | J Pharm Biomed Anal | pmid:18313250 |
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Kebaara BW et al. | Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction. | 2008 | Eukaryotic Cell | pmid:18424510 |
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Lorek J et al. | Influence of farnesol on the morphogenesis of Aspergillus niger. | 2008 | J. Basic Microbiol. | pmid:18383232 |
Marcuzzi A et al. | Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency. | 2008 | Pediatr. Res. | pmid:18391837 |
Chen CK et al. | The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity. | 2008 | J. Biol. Inorg. Chem. | pmid:18392864 |
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Bellahcène A et al. | Zoledronate inhibits alphavbeta3 and alphavbeta5 integrin cell surface expression in endothelial cells. | 2007 Mar-Apr | Endothelium | pmid:17497369 |
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Zhang L and Hill RP | Hypoxia enhances metastatic efficiency in HT1080 fibrosarcoma cells by increasing cell survival in lungs, not cell adhesion and invasion. | 2007 | Cancer Res. | pmid:17699784 |
Joo JH et al. | Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress response. | 2007 | Cancer Res. | pmid:17699800 |
Lee H et al. | Characterization of (E,E)-farnesol and its fatty acid esters from anal scent glands of nutria (Myocastor coypus) by gas chromatography-mass spectrometry and gas chromatography-infrared spectrometry. | 2007 | J Chromatogr A | pmid:17709112 |
Marciano D et al. | Neuroprotective effects of the Ras inhibitor S-trans-trans-farnesylthiosalicylic acid, measured by diffusion-weighted imaging after traumatic brain injury in rats. | 2007 | J. Neurotrauma | pmid:17711399 |
Fairn GD et al. | A chemogenomic screen in Saccharomyces cerevisiae uncovers a primary role for the mitochondria in farnesol toxicity and its regulation by the Pkc1 pathway. | 2007 | J. Biol. Chem. | pmid:17164236 |
Cetin A et al. | Angiotensin II-induced MAPK phosphorylation mediated by Ras and/or phospholipase C-dependent phosphorylations but not by protein kinase C phosphorylation in cultured rat vascular smooth muscle cells. | 2007 | Pharmacology | pmid:17135774 |