2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

Cross Reference

Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Leukemia, Myeloid D007951 52 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Dermatomycoses D003881 17 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Meningioma D008579 11 associated lipids
Neuritis, Autoimmune, Experimental D009444 4 associated lipids
Glioblastoma D005909 27 associated lipids
Nephritis D009393 19 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

Download all related citations
Per page 10 20 50 100 | Total 950
Authors Title Published Journal PubMed Link
Piérard GE et al. Miconazole, a pharmacological barrier to skin fungal infections. 2012 Expert Opin Pharmacother pmid:22568580
Qamar W et al. Benzo(a)pyrene-induced pulmonary inflammation, edema, surfactant dysfunction, and injuries in rats: alleviation by farnesol. 2012 Exp. Lung Res. pmid:22168545
Mans RA et al. Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. 2012 Neuroscience pmid:22192838
Mashiach-Farkash E et al. Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton. 2012 Oncotarget pmid:22776759
András IE et al. Lipid rafts and functional caveolae regulate HIV-induced amyloid beta accumulation in brain endothelial cells. 2012 Biochem. Biophys. Res. Commun. pmid:22490665
Mor A et al. Celecoxib enhances the anti-inflammatory effects of farnesylthiosalicylic acid on T cells independent of prostaglandin E(2) production. 2012 Inflammation pmid:22688643
Nasr N et al. HIV-1 infection of human macrophages directly induces viperin which inhibits viral production. 2012 Blood pmid:22677126
Cordeiro Rde A et al. Farnesol inhibits in vitro growth of the Cryptococcus neoformans species complex with no significant changes in virulence-related exoenzymes. 2012 Vet. Microbiol. pmid:22580194
Cerca N et al. Confocal laser scanning microscopy analysis of S. epidermidis biofilms exposed to farnesol, vancomycin and rifampicin. 2012 BMC Res Notes pmid:22591918
Costa CB et al. Farnesyltransferase inhibitors: molecular evidence of therapeutic efficacy in acute lymphoblastic leukemia through cyclin D1 inhibition. 2012 Anticancer Res. pmid:22399601
Wang X et al. Waikialoid A suppresses hyphal morphogenesis and inhibits biofilm development in pathogenic Candida albicans. 2012 J. Nat. Prod. pmid:22400916
Goldberg L et al. FTS and 2-DG induce pancreatic cancer cell death and tumor shrinkage in mice. 2012 Cell Death Dis pmid:22419113
Han TL et al. The metabolic response of Candida albicans to farnesol under hyphae-inducing conditions. 2012 FEMS Yeast Res. pmid:22846172
Chang W et al. Retigeric acid B attenuates the virulence of Candida albicans via inhibiting adenylyl cyclase activity targeted by enhanced farnesol production. 2012 PLoS ONE pmid:22848547
Lindsay AK et al. Farnesol and cyclic AMP signaling effects on the hypha-to-yeast transition in Candida albicans. 2012 Eukaryotic Cell pmid:22886999
Fu MS et al. Functional characterization of the small heat shock protein Hsp12p from Candida albicans. 2012 PLoS ONE pmid:22880130
Lichtor PA and Miller SJ Combinatorial evolution of site- and enantioselective catalysts for polyene epoxidation. 2012 Nat Chem pmid:23174978
Jamalian A et al. Chemical composition and antifungal activity of Matricaria recutita flower essential oil against medically important dermatophytes and soil-borne pathogens. 2012 J Mycol Med pmid:23518164
Green SA et al. Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis). 2012 J. Exp. Bot. pmid:22162874
Shin KO et al. Terpene alcohols inhibit de novo sphingolipid biosynthesis. 2012 Planta Med. pmid:22274813
Jin Y and Qiu FG A convergent stereocontrolled total synthesis of (-)-terpestacin. 2012 Org. Biomol. Chem. pmid:22710980
Mologni L et al. Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells. 2012 PLoS ONE pmid:23227266
Wartenberg D et al. Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin. 2012 J Proteomics pmid:22634043
Yu LH et al. Possible inhibitory molecular mechanism of farnesol on the development of fluconazole resistance in Candida albicans biofilm. 2012 Antimicrob. Agents Chemother. pmid:22106223
Oron T et al. Prevention of induced colitis in mice by the ras antagonist farnesylthiosalicylic acid. 2012 Dig. Dis. Sci. pmid:21901261
Stärkel P et al. Ras inhibition in hepatocarcinoma by S-trans-trans-farnesylthiosalicyclic acid: association of its tumor preventive effect with cell proliferation, cell cycle events, and angiogenesis. 2012 Mol. Carcinog. pmid:21882255
Berrocal A et al. Quorum sensing activity in Ophiostoma ulmi: effects of fusel oils and branched chain amino acids on yeast-mycelial dimorphism. 2012 J. Appl. Microbiol. pmid:22519968
Falsetta ML et al. Novel antibiofilm chemotherapy targets exopolysaccharide synthesis and stress tolerance in Streptococcus mutans to modulate virulence expression in vivo. 2012 Antimicrob. Agents Chemother. pmid:22985885
Gonçalves O et al. Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains. 2011 Mutat. Res. pmid:21453784
Ling Y et al. Novel nitric oxide-releasing derivatives of farnesylthiosalicylic acid: synthesis and evaluation of antihepatocellular carcinoma activity. 2011 J. Med. Chem. pmid:21504204
Jeon JG et al. Influences of trans-trans farnesol, a membrane-targeting sesquiterpenoid, on Streptococcus mutans physiology and survival within mixed-species oral biofilms. 2011 Int J Oral Sci pmid:21485314
Navarro-Moll MC et al. In vitro and in vivo activity of three sesquiterpenes against L(3) larvae of Anisakis type I. 2011 Exp. Parasitol. pmid:20932829
Huang J et al. Electrohydrodynamic deposition of nanotitanium doped hydroxyapatite coating for medical and dental applications. 2011 J Mater Sci Mater Med pmid:21243517
Hogan DA and Muhlschlegel FA Candida albicans developmental regulation: adenylyl cyclase as a coincidence detector of parallel signals. 2011 Curr. Opin. Microbiol. pmid:22014725
Krasowski MD et al. The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species. 2011 BMC Biochem. pmid:21291553
Bai C et al. Characterization of a hyperactive Cyr1 mutant reveals new regulatory mechanisms for cellular cAMP levels in Candida albicans. 2011 Mol. Microbiol. pmid:21992526
Endo S et al. Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol. 2011 Chem. Biol. Interact. pmid:21187079
Cortés M et al. Drimenol: A versatile synthon for compounds with trans-drimane skeleton. 2011 Nat Prod Commun pmid:21560760
Borbath I and Stärkel P Chemoprevention of hepatocellular carcinoma. Proof of concept in animal models. 2011 Acta Gastroenterol. Belg. pmid:21563652
Zhu J et al. Farnesol-induced apoptosis in Candida albicans is mediated by Cdr1-p extrusion and depletion of intracellular glutathione. 2011 PLoS ONE pmid:22205973
Piispanen AE et al. Roles of Ras1 membrane localization during Candida albicans hyphal growth and farnesol response. 2011 Eukaryotic Cell pmid:21908593
Charron G et al. Alkynyl-farnesol reporters for detection of protein S-prenylation in cells. 2011 Mol Biosyst pmid:21107478
Epplen R et al. Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines. 2011 Acta Oncol pmid:20429730
Bendena WG et al. Evidence for differential biosynthesis of juvenile hormone (and related) sesquiterpenoids in Drosophila melanogaster. 2011 Gen. Comp. Endocrinol. pmid:21354154
Nagai H et al. Development of a novel PPARγ ligand screening system using pinpoint fluorescence-probed protein. 2011 Biosci. Biotechnol. Biochem. pmid:21307572
Rahman NK et al. Enzymatic synthesis of farnesyl laurate in organic solvent: initial water activity, kinetics mechanism, optimization of continuous operation using packed bed reactor and mass transfer studies. 2011 Bioprocess Biosyst Eng pmid:21327986
Gori K et al. Alcohol-based quorum sensing plays a role in adhesion and sliding motility of the yeast Debaryomyces hansenii. 2011 FEMS Yeast Res. pmid:22093748
Mor A et al. Inhibition of contact sensitivity by farnesylthiosalicylic acid-amide, a potential Rap1 inhibitor. 2011 J. Invest. Dermatol. pmid:21716322
Tsuji F et al. The geranyl-modified tryptophan residue is crucial for ComXRO-E-2 pheromone biological activity. 2011 Bioorg. Med. Chem. Lett. pmid:21636272
Kaneko M et al. Effect of farnesol on mevalonate pathway of Staphylococcus aureus. 2011 J. Antibiot. pmid:21772307