| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arteriosclerosis | D001161 | 86 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
2E,6E-farnesol
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
Cross Reference
Introduction
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2E,6E-farnesol?
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
PubChem Associated disorders and diseases
What pathways are associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2E,6E-farnesol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2E,6E-farnesol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2E,6E-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Winder BS and Roberts PE | Characterization of the proteins from Melanoplus bivittatus that bind juvenile hormone, and a refined EFDA photolabeling technique. | 1992 | Int. J. Biochem. | pmid:1426524 |
| pmid:14296566 | ||||
| Brehm-Stecher BF and Johnson EA | Sensitization of Staphylococcus aureus and Escherichia coli to antibiotics by the sesquiterpenoids nerolidol, farnesol, bisabolol, and apritone. | 2003 | Antimicrob. Agents Chemother. | pmid:14506058 |
| Ownby SE and Hohl RJ | Isoprenoid alcohols restore protein isoprenylation in a time-dependent manner independent of protein synthesis. | 2003 | Lipids | pmid:14506838 |
| Mau CJ et al. | Protein farnesyltransferase inhibitors interfere with farnesyl diphosphate binding by rubber transferase. | 2003 | Eur. J. Biochem. | pmid:14511375 |
| Sever N et al. | Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol. | 2003 | J. Biol. Chem. | pmid:14563840 |
| Koo H et al. | Inhibition of Streptococcus mutans biofilm accumulation and polysaccharide production by apigenin and tt-farnesol. | 2003 | J. Antimicrob. Chemother. | pmid:14563892 |
| Shalom-Feuerstein R et al. | Restoration of sensitivity to anoikis in Ras-transformed rat intestinal epithelial cells by a Ras inhibitor. | 2004 | Cell Death Differ. | pmid:14576773 |
| Sakata T et al. | Chemical ecology of oribatid mites III. Chemical composition of oil gland exudates from two oribatid mites, Trhypochthoniellus sp. and Trhypochthonius japonicus (Acari: Trhypochthoniidae). | 2003 | Exp. Appl. Acarol. | pmid:14635814 |
| Li X et al. | New polyoxygenated farnesylcyclohexenones, deacetoxyyanuthone A and its hydro derivative from the marine-derived fungus Penicillium sp. | 2003 | J. Nat. Prod. | pmid:14640527 |
| McAnally JA et al. | Farnesyl-O-acetylhydroquinone and geranyl-O-acetylhydroquinone suppress the proliferation of murine B16 melanoma cells, human prostate and colon adenocarcinoma cells, human lung carcinoma cells, and human leukemia cells. | 2003 | Cancer Lett. | pmid:14643448 |
| George J et al. | Inhibition of intimal thickening in the rat carotid artery injury model by a nontoxic Ras inhibitor. | 2004 | Arterioscler. Thromb. Vasc. Biol. | pmid:14670932 |
| Grossman R et al. | Increase in peripheral benzodiazepine receptors and loss of glutamate NMDA receptors in a mouse model of closed head injury: a quantitative autoradiographic study. | 2003 | Neuroimage | pmid:14683703 |
| Ruiz-Velasco N et al. | Statins upregulate CD36 expression in human monocytes, an effect strengthened when combined with PPAR-gamma ligands Putative contribution of Rho GTPases in statin-induced CD36 expression. | 2004 | Biochem. Pharmacol. | pmid:14698043 |
| Lochnit G and Geyer R | Evidence for the presence of the Kennedy and Bremer- Greenberg pathways in Caenorhabditis elegans. | 2003 | Acta Biochim. Pol. | pmid:14740010 |
| Thorpe JL et al. | Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation. | 2004 | Dev. Cell | pmid:14960282 |
| Murataliev MB et al. | Chimeragenesis of the fatty acid binding site of cytochrome P450BM3. Replacement of residues 73-84 with the homologous residues from the insect cytochrome P450 CYP4C7. | 2004 | Biochemistry | pmid:14967018 |
| McPherson RA et al. | The novel Ras antagonist, farnesylthiosalicylate, suppresses growth of prostate cancer in vitro. | 2004 | Prostate | pmid:14968433 |
| Rowat AC and Davis JH | Farnesol-DMPC phase behaviour: a (2)H-NMR study. | 2004 | Biochim. Biophys. Acta | pmid:15003880 |
| Hornby JM et al. | Inoculum size effect in dimorphic fungi: extracellular control of yeast-mycelium dimorphism in Ceratocystis ulmi. | 2004 | Appl. Environ. Microbiol. | pmid:15006753 |