Meigs TE et al. |
Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo. |
1996 |
J. Biol. Chem. |
pmid:8626470
|
Tachibana A et al. |
Evidence for farnesol-mediated isoprenoid synthesis regulation in a halophilic archaeon, Haloferax volcanii. |
1996 |
FEBS Lett. |
pmid:8566226
|
Satoh T et al. |
The effects of pravastatin, an HMG-CoA reductase inhibitor, on cell viability and DNA production of rat hepatocytes. |
1996 |
Life Sci. |
pmid:8831797
|
Nishio E et al. |
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor impairs cell p4fferentiation in cultured adipogenic cells (3T3-L1). |
1996 |
Eur. J. Pharmacol. |
pmid:8773465
|
Carel K et al. |
Insulin stimulates mitogen-activated protein kinase by a Ras-independent pathway in 3T3-L1 adipocytes. |
1996 |
J. Biol. Chem. |
pmid:8940037
|
Willumsen BM et al. |
Novel determinants of H-Ras plasma membrane localization and transformation. |
1996 |
Oncogene |
pmid:8934536
|
Vogt A et al. |
Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts. |
1996 |
Oncogene |
pmid:8934546
|
Tisch D et al. |
Activation of signaling pathways in HL60 cells and human neutrophils by farnesylthiosalicylate. |
1996 |
Eur. J. Biochem. |
pmid:9022678
|
McGuire TF et al. |
Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation. |
1996 |
J. Biol. Chem. |
pmid:8910319
|
Miquel K et al. |
Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells. |
1996 |
Biochem. Biophys. Res. Commun. |
pmid:8780704
|
Keller RK et al. |
Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver. |
1996 |
Arch. Biochem. Biophys. |
pmid:8645011
|
Koyama T et al. |
Identification of significant residues in the substrate binding site of Bacillus stearothermophilus farnesyl diphosphate synthase. |
1996 |
Biochemistry |
pmid:8755734
|
Umetani N et al. |
Lovastatin inhibits gene expression of type-I scavenger receptor in THP-1 human macrophages. |
1996 |
Biochim. Biophys. Acta |
pmid:8908154
|
Roullet JB et al. |
Farnesyl analogues inhibit vasoconstriction in animal and human arteries. |
1996 |
J. Clin. Invest. |
pmid:8636420
|
O'Brien ML et al. |
Convergence of three steroid receptor pathways in the mediation of nongenotoxic hepatocarcinogenesis. |
1996 |
Carcinogenesis |
pmid:8625436
|
Kisselev O et al. |
Efficient interaction with a receptor requires a specific type of prenyl group on the G protein gamma subunit. |
1995 |
J. Biol. Chem. |
pmid:7592699
|
Corsini A et al. |
Pathogenesis of atherosclerosis and the role of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. |
1995 |
Am. J. Cardiol. |
pmid:7604791
|
Crick DC et al. |
Farnesol is utilized for protein isoprenylation and the biosynthesis of cholesterol in mammalian cells. |
1995 |
Biochem. Biophys. Res. Commun. |
pmid:7794274
|
Meigs TE et al. |
Farnesyl acetate, a derivative of an isoprenoid of the mevalonate pathway, inhibits DNA replication in hamster and human cells. |
1995 |
Exp. Cell Res. |
pmid:7641798
|
Yazlovitskaya EM and Melnykovych G |
Selective farnesol toxicity and translocation of protein kinase C in neoplastic HeLa-S3K and non-neoplastic CF-3 cells. |
1995 |
Cancer Lett. |
pmid:7874691
|
Forman BM et al. |
Identification of a nuclear receptor that is activated by farnesol metabolites. |
1995 |
Cell |
pmid:7774010
|
Voziyan PA et al. |
Mechanism of farnesol cytotoxicity: further evidence for the role of PKC-dependent signal transduction in farnesol-induced apoptotic cell death. |
1995 |
Biochem. Biophys. Res. Commun. |
pmid:7626062
|
Marom M et al. |
Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid. |
1995 |
J. Biol. Chem. |
pmid:7673206
|
Gilbert BA et al. |
Farnesyl thiotriazole, a potent neutrophil agonist and structurally novel activator of protein kinase C. |
1995 |
Biochemistry |
pmid:7696255
|
Fliesler SJ and Keller RK |
Metabolism of [3H]farnesol to cholesterol and cholesterogenic intermediates in the living rat eye. |
1995 |
Biochem. Biophys. Res. Commun. |
pmid:7763243
|
Marciano D et al. |
Farnesyl derivatives of rigid carboxylic acids-inhibitors of ras-dependent cell growth. |
1995 |
J. Med. Chem. |
pmid:7731012
|
Epand RM et al. |
Lipid-mediated a-factor interactions with artificial membranes. |
1995 |
Meth. Enzymol. |
pmid:7651149
|
Parmryd I et al. |
Identification of spinach farnesyl protein transferase. Dithiothreitol as an acceptor in vitro. |
1995 |
Eur. J. Biochem. |
pmid:8575428
|
Søgaard M et al. |
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. |
1994 |
Cell |
pmid:7923363
|
Biermann BJ et al. |
Novel isoprenylated proteins identified by an expression library screen. |
1994 |
J. Biol. Chem. |
pmid:7929216
|
Munro E et al. |
Inhibition of human vascular smooth muscle cell proliferation by lovastatin: the role of isoprenoid intermediates of cholesterol synthesis. |
1994 |
Eur. J. Clin. Invest. |
pmid:7890015
|
Tojo K et al. |
Diffusion and metabolism of prednisolone farnesylate in viable skin of the hairless mouse. |
1994 |
Pharm. Res. |
pmid:8008705
|
Fukada Y et al. |
Effects of carboxyl methylation of photoreceptor G protein gamma-subunit in visual transduction. |
1994 |
J. Biol. Chem. |
pmid:8106497
|
Caldwell GA et al. |
Consequences of altered isoprenylation targets on a-factor export and bioactivity. |
1994 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:8108401
|
Kothapalli R et al. |
Effects of long-chain fatty amines on the growth of ras-transformed NIH 3T3 cells. |
1994 |
Biochem. Pharmacol. |
pmid:8204109
|
Inoue H et al. |
Phosphorylation of farnesol by a cell-free system from Botryococcus braunii. |
1994 |
Biochem. Biophys. Res. Commun. |
pmid:8179579
|
Bondar OP et al. |
Effects of farnesol on the thermotropic behavior of dimyristoylphosphatidylcholine. |
1994 |
Chem. Phys. Lipids |
pmid:7820904
|
Aronheim A et al. |
Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. |
1994 |
Cell |
pmid:7923364
|
Haug JS et al. |
Directed cell killing (apoptosis) in human lymphoblastoid cells incubated in the presence of farnesol: effect of phosphatidylcholine. |
1994 |
Biochim. Biophys. Acta |
pmid:8061045
|
Kisselev OG et al. |
A farnesylated domain in the G protein gamma subunit is a specific determinant of receptor coupling. |
1994 |
J. Biol. Chem. |
pmid:8063769
|
Lübben M and Morand K |
Novel prenylated hemes as cofactors of cytochrome oxidases. Archaea have modified hemes A and O. |
1994 |
J. Biol. Chem. |
pmid:8063781
|
Neuhüser T et al. |
Responsiveness of the adult cricket (Gryllus bimaculatus and Acheta domesticus) retrocerebral complex to allatostatin-1 from a cockroach, Diploptera punctata. |
1994 |
J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. |
pmid:8014257
|
Adany I et al. |
Differences in sensitivity to farnesol toxicity between neoplastically- and non-neoplastically-derived cells in culture. |
1994 |
Cancer Lett. |
pmid:8019976
|
Correll CC et al. |
Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. |
1994 |
J. Biol. Chem. |
pmid:8021239
|
Mallat A et al. |
Effect of simvastatin, an inhibitor of hydroxy-methylglutaryl coenzyme A reductase, on the growth of human Ito cells. |
1994 |
Hepatology |
pmid:7982659
|
Cox AD et al. |
The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation. |
1994 |
J. Biol. Chem. |
pmid:8034681
|
Akopyan TN et al. |
Proteolytic processing of farnesylated peptides: assay and partial purification from pig brain membranes of an endopeptidase which has the characteristics of E.C. 3.4.24.15. |
1994 |
Biochem. Biophys. Res. Commun. |
pmid:8297391
|
Prashad M et al. |
N-(arylalkyl)farnesylamines: new potent squalene synthetase inhibitors. |
1993 |
J. Med. Chem. |
pmid:8496919
|
Gibbs JB et al. |
Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. |
1993 |
J. Biol. Chem. |
pmid:8463291
|
Foster JM et al. |
Biosynthesis of isoprenoid compounds in Schistosoma mansoni. |
1993 |
Mol. Biochem. Parasitol. |
pmid:8264731
|
Inoue H et al. |
Formation of farnesal and 3-hydroxy-2,3-dihydrofarnesal from farnesol by protoplasts of Botryococcus braunii. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:8250896
|
Corsini A et al. |
Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase. |
1993 |
Atherosclerosis |
pmid:8216498
|
Voziyan PA et al. |
Farnesol inhibits phosphatidylcholine biosynthesis in cultured cells by decreasing cholinephosphotransferase activity. |
1993 |
Biochem. J. |
pmid:8240288
|
Kothapalli R et al. |
Farnesylamine: an inhibitor of farnesylation and growth of ras-transformed cells. |
1993 |
Lipids |
pmid:8277827
|
Touhara K and Prestwich GD |
Juvenile hormone epoxide hydrolase. Photoaffinity labeling, purification, and characterization from tobacco hornworm eggs. |
1993 |
J. Biol. Chem. |
pmid:8396141
|
O'Donnell MP et al. |
Lovastatin inhibits proliferation of rat mesangial cells. |
1993 |
J. Clin. Invest. |
pmid:8423236
|
Touhara K and Prestwich GD |
Binding site mapping of a photoaffinity-labeled juvenile hormone binding protein. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1734862
|
Lutz RJ et al. |
Nucleoplasmic localization of prelamin A: implications for prenylation-dependent lamin A assembly into the nuclear lamina. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1557405
|
Newman CM et al. |
Post-translational processing of Schizosaccharomyces pombe YPT proteins. |
1992 |
J. Biol. Chem. |
pmid:1597466
|
Ma YT and Rando RR |
A microsomal endoprotease that specifically cleaves isoprenylated peptides. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1631119
|
Kato K et al. |
Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1631135
|
Havel CM and Watson JA |
Isopentenoid synthesis in isolated embryonic Drosophila cells: absolute, basal mevalonate synthesis rate determination. |
1992 |
Arch. Biochem. Biophys. |
pmid:1567218
|
Bradfute DL et al. |
Squalene synthase-deficient mutant of Chinese hamster ovary cells. |
1992 |
J. Biol. Chem. |
pmid:1526971
|
Bai M and Prestwich GD |
Inhibition and activation of porcine squalene epoxidase. |
1992 |
Arch. Biochem. Biophys. |
pmid:1536566
|
Melnykovych G et al. |
Growth inhibition of leukemia cell line CEM-C1 by farnesol: effects of phosphatidylcholine and diacylglycerol. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1632790
|
Sobotka-Briner C and Chelsky D |
COOH-terminal methylation of lamin B and inhibition of methylation by farnesylated peptides corresponding to lamin B and other CAAX motif proteins. |
1992 |
J. Biol. Chem. |
pmid:1601879
|
Pérez-Sala D et al. |
Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates. |
1992 |
Biochem. J. |
pmid:1622400
|
Cox AD et al. |
Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein. |
1992 |
Mol. Cell. Biol. |
pmid:1375323
|
Shindo T et al. |
A farnesyl arabinoside as an enhancer of glucose transport in rat adipocytes from a soft coral, Sinularia sp. |
1992 |
Experientia |
pmid:1353460
|
Okazaki S et al. |
[A 13-week subcutaneous toxicity study of prednisolone farnesylate (PNF) in rats]. |
1992 |
J Toxicol Sci |
pmid:1293320
|
Nagashima Y et al. |
[A 13-week percutaneous toxicity study of prednisolone farnesylate (PNF) gel in beagle dogs with a recovery period of 5 weeks]. |
1992 |
J Toxicol Sci |
pmid:1293321
|
Nagashima Y et al. |
[A 52-week percutaneous toxicity study of prednisolone farnesylate (PNF) gel in beagle dogs with a recovery period of 8 weeks]. |
1992 |
J Toxicol Sci |
pmid:1293322
|
Taniguchi H et al. |
[Reproductive and developmental toxicity study of prednisolone farnesylate (PNF)--study by subcutaneous administration of PNF prior to and in the early stages of pregnancy in rats]. |
1992 |
J Toxicol Sci |
pmid:1293323
|
Taniguchi H et al. |
[Reproductive and developmental toxicity study of prednisolone farnesylate (PNF)--study by subcutaneous administration of PNF during the period of fetal organogenesis in rats]. |
1992 |
J Toxicol Sci |
pmid:1293324
|
Aso S et al. |
[Reproductive and developmental toxicity study of prednisolone farnesylate (PNF)--teratogenicity study in rabbits by subcutaneous administration]. |
1992 |
J Toxicol Sci |
pmid:1293325
|
Taniguchi H et al. |
[Reproductive and developmental toxicity study of prednisolone farnesylate (PNF)--study of subcutaneous administration of PNF during the perinatal and lactation periods in rats]. |
1992 |
J Toxicol Sci |
pmid:1293326
|
Otsuka M et al. |
[Mutagenicity studies of prednisolone farnesylate (PNF)]. |
1992 |
J Toxicol Sci |
pmid:1293327
|
Uchiyama H et al. |
[Effects of prednisolone farnesylate (PNF) gel on skin and ocular mucosa]. |
1992 |
J Toxicol Sci |
pmid:1293328
|
Okazaki S et al. |
[A 13-week dermal toxicity study of prednisolone farnesylate (PNF) gel in rats with a recovery period of 5 weeks]. |
1992 |
J Toxicol Sci |
pmid:1293330
|
Okazaki S et al. |
[A 52-week dermal toxicity study of prednisolone farnesylate (PNF) gel in rats with a recovery period of 8 weeks]. |
1992 |
J Toxicol Sci |
pmid:1293331
|
Akopyan TN et al. |
Cleavage of farnesylated COOH-terminal heptapeptide of mouse N-ras by brain microsomal membranes: evidence for a carboxypeptidase which specifically removes the COOH-terminal methionine. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1417809
|
Winder BS and Roberts PE |
Characterization of the proteins from Melanoplus bivittatus that bind juvenile hormone, and a refined EFDA photolabeling technique. |
1992 |
Int. J. Biochem. |
pmid:1426524
|
Anant JS and Fung BK |
In vivo farnesylation of rat rhodopsin kinase. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1550556
|
Lowe PN et al. |
Expression of polyisoprenylated Ras proteins in the insect/baculovirus system. |
1992 |
Biochem. Soc. Trans. |
pmid:1397645
|
Nigg EA et al. |
Targeting lamin proteins to the nuclear envelope: the role of CaaX box modifications. |
1992 |
Biochem. Soc. Trans. |
pmid:1397650
|
Dionigi CP et al. |
Effects of farnesol and the off-flavor derivative geosmin on Streptomyces tendae. |
1991 |
Appl. Environ. Microbiol. |
pmid:1785920
|
Ohguro H et al. |
Carboxyl methylation and farnesylation of transducin gamma-subunit synergistically enhance its coupling with metarhodopsin II. |
1991 |
EMBO J. |
pmid:1935895
|
Fujiyama A et al. |
S-farnesylation and methyl esterification of C-terminal domain of yeast RAS2 protein prior to fatty acid acylation. |
1991 |
J. Biol. Chem. |
pmid:1917931
|
Keung WM |
Human liver alcohol dehydrogenases catalyze the oxidation of the intermediary alcohols of the shunt pathway of mevalonate metabolism. |
1991 |
Biochem. Biophys. Res. Commun. |
pmid:1993065
|
Aclé D et al. |
Activity of the corpora allata of adult female Leucophaea maderae: effects of mating and feeding. |
1990 |
Arch. Insect Biochem. Physiol. |
pmid:2134173
|
Lerro KA and Prestwich GD |
Cloning and sequencing of a cDNA for the hemolymph juvenile hormone binding protein of larval Manduca sexta. |
1990 |
J. Biol. Chem. |
pmid:2246263
|
Fukada Y et al. |
Farnesylated gamma-subunit of photoreceptor G protein indispensable for GTP-binding. |
1990 |
Nature |
pmid:2385292
|
Jackson JH et al. |
Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation. |
1990 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:2183224
|
Lai RK et al. |
The gamma subunit of transducin is farnesylated. |
1990 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:2217200
|
Goldstein JL and Brown MS |
Regulation of the mevalonate pathway. |
1990 |
Nature |
pmid:1967820
|
Prestwich GD et al. |
Binding proteins for methyl farnesoate in lobster tissues: detection by photoaffinity labeling. |
1990 |
Gen. Comp. Endocrinol. |
pmid:2074002
|
Ershova LS et al. |
[The action of a juvenile hormone synthetic analog--ether-farnesol on Xenopsylla cheopis fleas]. |
1989 Sep-Oct |
Parazitologia |
pmid:2616197
|
Lowy DR and Willumsen BM |
Protein modification: new clue to Ras lipid glue. |
1989 |
Nature |
pmid:2677741
|
Mohamed MA et al. |
Polyacrylamide gel miniaturization improves protein visualization and autoradiographic detection. |
1989 |
Anal. Biochem. |
pmid:2729547
|
Vandewaa EA et al. |
Physiological role of HMG-CoA reductase in regulating egg production by Schistosoma mansoni. |
1989 |
Am. J. Physiol. |
pmid:2782464
|