| MeSH term | MeSH ID | Detail |
|---|---|---|
| Precancerous Conditions | D011230 | 48 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Leukemia, Myeloid, Acute | D015470 | 19 associated lipids |
| HIV Infections | D015658 | 20 associated lipids |
| Head Injuries, Closed | D016489 | 5 associated lipids |
| Anisakiasis | D017129 | 2 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Nerve Sheath Neoplasms | D018317 | 4 associated lipids |
2E,6E-farnesol
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
Cross Reference
Introduction
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2E,6E-farnesol?
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
PubChem Associated disorders and diseases
What pathways are associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2E,6E-farnesol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2E,6E-farnesol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2E,6E-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Duncan RE and Archer MC | Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes. | 2008 | Lipids | pmid:18509688 |
| Zhao M et al. | Determination of salirasib (S-trans,trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry. | 2008 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:18534927 |
| Mor A et al. | N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells. | 2008 | Eur. J. Immunol. | pmid:18461565 |
| Savoldi M et al. | Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase. | 2008 | Mol. Microbiol. | pmid:18681941 |
| Kotti T et al. | Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18685105 |
| Muramatsu M et al. | Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols. | 2008 | J. Biosci. Bioeng. | pmid:18930003 |
| Qamar W and Sultana S | Farnesol ameliorates massive inflammation, oxidative stress and lung injury induced by intratracheal instillation of cigarette smoke extract in rats: an initial step in lung chemoprevention. | 2008 | Chem. Biol. Interact. | pmid:18793622 |
| Peleg AY et al. | Prokaryote-eukaryote interactions identified by using Caenorhabditis elegans. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18794525 |
| Haklai R et al. | Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice. | 2008 | Cancer Chemother. Pharmacol. | pmid:17909812 |
| Zvibel I et al. | The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells. | 2008 | Dig. Dis. Sci. | pmid:17934818 |
| Journe F et al. | Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. | 2008 | Breast Cancer Res. Treat. | pmid:17333335 |
| da Silva Morais A et al. | Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats. | 2008 | Clin. Sci. | pmid:17678500 |
| Shchepin R et al. | Influence of heterocyclic and oxime-containing farnesol analogs on quorum sensing and pathogenicity in Candida albicans. | 2008 | Bioorg. Med. Chem. | pmid:18037299 |
| Blum R et al. | Inhibitors of chronically active ras: potential for treatment of human malignancies. | 2008 | Recent Pat Anticancer Drug Discov | pmid:18289122 |
| Tsangarakis C et al. | Zeolite NaY-promoted cyclization of farnesal: a short route to nanaimoal. | 2008 | J. Org. Chem. | pmid:18321121 |
| McAlester G et al. | Signal-mediated interactions between Pseudomonas aeruginosa and Candida albicans. | 2008 | J. Med. Microbiol. | pmid:18436588 |
| Joo JH and Jetten AM | NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway. | 2008 | J. Biol. Chem. | pmid:18424438 |
| Kebaara BW et al. | Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction. | 2008 | Eukaryotic Cell | pmid:18424510 |
| Rotblat B et al. | The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer. | 2008 | Meth. Enzymol. | pmid:18374183 |
| Lorek J et al. | Influence of farnesol on the morphogenesis of Aspergillus niger. | 2008 | J. Basic Microbiol. | pmid:18383232 |