2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
HIV Infections D015658 20 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Neurilemmoma D009442 10 associated lipids
Head Injuries, Closed D016489 5 associated lipids
Insulin Resistance D007333 99 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Neuralgia D009437 28 associated lipids
Lung Injury D055370 14 associated lipids
Neoplasms, Glandular and Epithelial D009375 12 associated lipids
Nerve Sheath Neoplasms D018317 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

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Authors Title Published Journal PubMed Link
Fioravanti CF and MacInnis AJ The in vitro effects of farnesol and derivatives on Hymenolepis diminuta. 1976 J. Parasitol. pmid:978365
Hanson JR and Nyfeler R Studies in terpenoid biosynthesis. Part 18. Biosynthesis of culmorin. 1976 J. Chem. Soc. Perkin Trans. I pmid:1034641
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de Montellano PR et al. Inhibition of squalene synthetase by farnesyl pyrophosphate analogues. 1977 J. Med. Chem. pmid:189031
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Ortiz de Montellano PR et al. Substrate selectivity of squalene synthetase. 1977 Biochemistry pmid:329862
Fioravanti CF and MacInnis AJ The identification and characterization of a prenoid constituent (farnesol) of Hymenolepis diminuta (Cestoda). 1977 Comp. Biochem. Physiol., B pmid:299634
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L'Hélias C [Study on deshydrogenases implicated in control of farnesol and juvenile hormone metabolisms in Pieris brassicae (author's transl)]. 1977 Ann. Endocrinol. (Paris) pmid:612274
Peter MG et al. [Identification of farnesol as an intermediate in the biosynthesis of cantharidin from mevalonolactone]. 1977 Helv. Chim. Acta pmid:599044
Micciarelli AS Effects of farnesyl methyl ether on embryos of Schistocerca Gregaria (Orthoptera). 1977 Acta Embryol Exp (Palermo) pmid:605750
Boisvenue RJ et al. Haemonchus contortus: effects of compounds with juvenile hormone activity on the in vitro development of infective larvae. 1977 Exp. Parasitol. pmid:862711
Peter MG et al. [Incorporation experiments with (3H and 14C) doubly labelled farnesols into cantharidin (author's transl)]. 1977 Helv. Chim. Acta pmid:893117
Styczyńska B et al. [2,3-methylenefarnesenic acid derivatives as juvenile hormone analogs against housefly (Musca domestica L.)]. 1977 Wiad Parazytol pmid:899003
King HL and Rilling HC Avian liver prenyltransferase. The role of metal in substrate binding and the orientation of substrates during catalysis. 1977 Biochemistry pmid:901755
Gavey KL and Scallen TJ Nonparticipation of 105,000 x g liver supernatant or sterol carrier protein in the enzymatic conversion of farnesyl pyrophosphate to squalene by rat liver microsomes. 1978 J. Biol. Chem. pmid:209043
Baba T and Allen CM Substrate specificity of undecaprenyl pyrophosphate synthetase from Lactobacillus plantarum. 1978 Biochemistry pmid:728420
Tsuchiya E and Fukui S Binding of rhodotorucine A, a lipopeptidyl mating hormone, to a cells of Rhodosporidium toruloides for induction of sexual differentiation. 1978 Biochem. Biophys. Res. Commun. pmid:743290
Agnew WS and Popják G Squalene synthetase. Stoichiometry and kinetics of presqualene pyrophosphate and squalene synthesis by yeast microsomes. 1978 J. Biol. Chem. pmid:26684