2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
HIV Infections D015658 20 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Neurilemmoma D009442 10 associated lipids
Head Injuries, Closed D016489 5 associated lipids
Insulin Resistance D007333 99 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Neuralgia D009437 28 associated lipids
Lung Injury D055370 14 associated lipids
Neoplasms, Glandular and Epithelial D009375 12 associated lipids
Nerve Sheath Neoplasms D018317 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

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Authors Title Published Journal PubMed Link
Piérard GE et al. Miconazole, a pharmacological barrier to skin fungal infections. 2012 Expert Opin Pharmacother pmid:22568580
Goldberg L et al. FTS and 2-DG induce pancreatic cancer cell death and tumor shrinkage in mice. 2012 Cell Death Dis pmid:22419113
Han TL et al. The metabolic response of Candida albicans to farnesol under hyphae-inducing conditions. 2012 FEMS Yeast Res. pmid:22846172
Chang W et al. Retigeric acid B attenuates the virulence of Candida albicans via inhibiting adenylyl cyclase activity targeted by enhanced farnesol production. 2012 PLoS ONE pmid:22848547
Lindsay AK et al. Farnesol and cyclic AMP signaling effects on the hypha-to-yeast transition in Candida albicans. 2012 Eukaryotic Cell pmid:22886999
Fu MS et al. Functional characterization of the small heat shock protein Hsp12p from Candida albicans. 2012 PLoS ONE pmid:22880130
Jin Y and Qiu FG A convergent stereocontrolled total synthesis of (-)-terpestacin. 2012 Org. Biomol. Chem. pmid:22710980
Mologni L et al. Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells. 2012 PLoS ONE pmid:23227266
Oron T et al. Prevention of induced colitis in mice by the ras antagonist farnesylthiosalicylic acid. 2012 Dig. Dis. Sci. pmid:21901261
Stärkel P et al. Ras inhibition in hepatocarcinoma by S-trans-trans-farnesylthiosalicyclic acid: association of its tumor preventive effect with cell proliferation, cell cycle events, and angiogenesis. 2012 Mol. Carcinog. pmid:21882255