MeSH term | MeSH ID | Detail |
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Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Muramatsu M et al. | Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms. | 2008 | Appl. Microbiol. Biotechnol. | pmid:18636253 |
Brockmann H and Knobloch G | [A new bacteriochlorophyll from Rhodospirillum rubrum]. | 1972 | Arch Mikrobiol | pmid:4627398 |
Bai M and Prestwich GD | Inhibition and activation of porcine squalene epoxidase. | 1992 | Arch. Biochem. Biophys. | pmid:1536566 |
Keenan MV and Allen CM | Characterization of undecaprenyl pyrophosphate synthetase from Lactobacillus plantarum. | 1974 | Arch. Biochem. Biophys. | pmid:4599964 |
Dugan RE and Porter JW | Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction. | 1972 | Arch. Biochem. Biophys. | pmid:4403691 |
Meigs TE and Simoni RD | Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase. | 1997 | Arch. Biochem. Biophys. | pmid:9281305 |
Krishna G et al. | Enzymic conversion of farnesyl pyrophosphate to squalene. | 1966 | Arch. Biochem. Biophys. | pmid:4380977 |
Desrosiers RR and Béliveau R | Regulation by GTPgammaS of protein carboxylmethyltransferase activity in kidney brush border membranes. | 1998 | Arch. Biochem. Biophys. | pmid:9514644 |
Baba T et al. | Dehydrodolichyl diphosphate synthetase from rat seminiferous tubules. | 1987 | Arch. Biochem. Biophys. | pmid:3813545 |
Xu L and Simoni RD | The inhibition of degradation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase by sterol regulatory element binding protein cleavage-activating protein requires four phenylalanine residues in span 6 of HMG-CoA reductase transmembrane domain. | 2003 | Arch. Biochem. Biophys. | pmid:12781775 |