MeSH term | MeSH ID | Detail |
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Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Banfi C et al. | Proteomic analysis of human low-density lipoprotein reveals the presence of prenylcysteine lyase, a hydrogen peroxide-generating enzyme. | 2009 | Proteomics | pmid:19253276 |
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Gomes FI et al. | Effect of farnesol on planktonic and biofilm cells of Staphylococcus epidermidis. | 2009 | Curr. Microbiol. | pmid:19365686 |
Shirtliff ME et al. | Farnesol-induced apoptosis in Candida albicans. | 2009 | Antimicrob. Agents Chemother. | pmid:19364863 |
Chen F et al. | Tooth-binding micelles for dental caries prevention. | 2009 | Antimicrob. Agents Chemother. | pmid:19704121 |
Goldberg L et al. | New derivatives of farnesylthiosalicylic acid (salirasib) for cancer treatment: farnesylthiosalicylamide inhibits tumor growth in nude mice models. | 2009 | J. Med. Chem. | pmid:19072665 |
Ohto C et al. | Prenyl alcohol production by expression of exogenous isopentenyl diphosphate isomerase and farnesyl diphosphate synthase genes in Escherichia coli. | 2009 | Biosci. Biotechnol. Biochem. | pmid:19129660 |
Décanis N et al. | Farnesol promotes epithelial cell defense against Candida albicans through Toll-like receptor 2 expression, interleukin-6 and human beta-defensin 2 production. | 2009 | Cytokine | pmid:19121950 |
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Chaudhary SC et al. | Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: involvement of inflammation, Ras-ERK pathway and apoptosis. | 2009 | Life Sci. | pmid:19470390 |
Kraitzer A et al. | Novel farnesylthiosalicylate (FTS)-eluting composite structures. | 2009 | Eur J Pharm Sci | pmid:19491026 |
Mor A et al. | Ras inhibition increases the frequency and function of regulatory T cells and attenuates type-1 diabetes in non-obese diabetic mice. | 2009 | Eur. J. Pharmacol. | pmid:19527709 |
Muramatsu M et al. | Alkaline pH enhances farnesol production by Saccharomyces cerevisiae. | 2009 | J. Biosci. Bioeng. | pmid:19577192 |
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Abe S et al. | Suppression of anti-Candida activity of macrophages by a quorum-sensing molecule, farnesol, through induction of oxidative stress. | 2009 | Microbiol. Immunol. | pmid:19493200 |
Derengowski LS et al. | Antimicrobial effect of farnesol, a Candida albicans quorum sensing molecule, on Paracoccidioides brasiliensis growth and morphogenesis. | 2009 | Ann. Clin. Microbiol. Antimicrob. | pmid:19402910 |
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Pando R et al. | Ras inhibition attenuates myocardial ischemia-reperfusion injury. | 2009 | Biochem. Pharmacol. | pmid:19426696 |
Schneider-Merck T et al. | The Ras inhibitor farnesylthiosalicyclic acid (FTS) prevents nodule formation and development of preneoplastic foci of altered hepatocytes in rats. | 2009 | Eur. J. Cancer | pmid:19427195 |
Unnanuntana A et al. | The effects of farnesol on Staphylococcus aureus biofilms and osteoblasts. An in vitro study. | 2009 | J Bone Joint Surg Am | pmid:19884443 |
Mayoral JG et al. | NADP+-dependent farnesol dehydrogenase, a corpora allata enzyme involved in juvenile hormone synthesis. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19940247 |
Langford ML et al. | Cellular interactions of farnesol, a quorum-sensing molecule produced by Candida albicans. | 2009 | Future Microbiol | pmid:19995193 |
Jeon JG et al. | Influences of naturally occurring agents in combination with fluoride on gene expression and structural organization of Streptococcus mutans in biofilms. | 2009 | BMC Microbiol. | pmid:19863808 |
Raptis C et al. | Acid-catalyzed cyclization of terpenes under homogeneous and heterogeneous conditions as probed through stereoisotopic studies: a concerted process with competing preorganized chair and boat transition states. | 2009 | Chemistry | pmid:19780112 |
Xiao Y et al. | A two-component female-produced pheromone of the spider Pholcus beijingensis. | 2009 | J. Chem. Ecol. | pmid:19579045 |
Zhao M et al. | Determination of salirasib (S-trans,trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry. | 2008 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:18534927 |
Mor A et al. | N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells. | 2008 | Eur. J. Immunol. | pmid:18461565 |