MeSH term | MeSH ID | Detail |
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Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Willumsen BM et al. | Novel determinants of H-Ras plasma membrane localization and transformation. | 1996 | Oncogene | pmid:8934536 |
Vogt A et al. | Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts. | 1996 | Oncogene | pmid:8934546 |
Hanker AB et al. | Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling. | 2010 | Oncogene | pmid:19838215 |
Weisz B et al. | A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice. | 1999 | Oncogene | pmid:10353601 |
Shack S et al. | Activation of the cholesterol pathway and Ras maturation in response to stress. | 1999 | Oncogene | pmid:10557091 |
Jones S et al. | β-ionone induces cell cycle arrest and apoptosis in human prostate tumor cells. | 2013 | Nutr Cancer | pmid:23659452 |
Cho T and Aoyama T | [Quorum sensing in fungal pathogenesis]. | 2008 | Nippon Rinsho | pmid:19069092 |
Kogo Y and kato J | [Malignant tumor and apoptosis]. | 1997 | Nippon Naika Gakkai Zasshi | pmid:9410963 |
Cho T et al. | [Farnesol as a quorum-sensing molecule in Candida albicans]. | 2008 | Nihon Ishinkin Gakkai Zasshi | pmid:19001754 |
Cho T et al. | Transcriptional changes in Candida albicans Genes by both farnesol and high cell density at an early stage of morphogenesis in N-acetyl-D-glucosamine medium. | 2007 | Nihon Ishinkin Gakkai Zasshi | pmid:17975531 |
Mans RA et al. | Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. | 2012 | Neuroscience | pmid:22192838 |
Binda C et al. | Structure of the human mitochondrial monoamine oxidase B: new chemical implications for neuroprotectant drug design. | 2006 | Neurology | pmid:17030739 |
Grossman R et al. | Increase in peripheral benzodiazepine receptors and loss of glutamate NMDA receptors in a mouse model of closed head injury: a quantitative autoradiographic study. | 2003 | Neuroimage | pmid:14683703 |
Scheper MA et al. | Farnesol, a fungal quorum-sensing molecule triggers apoptosis in human oral squamous carcinoma cells. | 2008 | Neoplasia | pmid:18714396 |
Levinson HZ | [The evolution and biosynthesis of the terpinoid pheromones and hormones]. | 1972 | Naturwissenschaften | pmid:4571813 |
Emmerich H and Thiele HU | [Effect of farnesyl methyl ether on maturation of the Pterostichus nigrita F ovary]. | 1969 | Naturwissenschaften | pmid:5375112 |
Nair KK | Susceptibility of mosquito larvae to a synthetic juvenile hormone, farnesyl diethylamine. | 1967 | Naturwissenschaften | pmid:4384815 |
Fukada Y et al. | Farnesylated gamma-subunit of photoreceptor G protein indispensable for GTP-binding. | 1990 | Nature | pmid:2385292 |
Lowy DR and Willumsen BM | Protein modification: new clue to Ras lipid glue. | 1989 | Nature | pmid:2677741 |
Huelin FE and Murray KE | Alpha-farnesene in the natural coating of apples. | 1966 | Nature | pmid:5967802 |