2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Candidiasis, Invasive D058365 2 associated lipids
Anisakiasis D017129 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

Download all related citations
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Authors Title Published Journal PubMed Link
Rudi A et al. Likonides A and B: new ansa farnesyl quinols from the marine sponge Hyatella sp. 2004 Org. Lett. pmid:15496087
Bhavnani BR and Woolever CA Formation of steroids by the pregnant mare. VI. Metabolism of [14C]farnesyl pyrophosphate and [3H]dehydroepiandrosterone injected into the fetus. 1978 Endocrinology pmid:155006
Anant JS and Fung BK In vivo farnesylation of rat rhodopsin kinase. 1992 Biochem. Biophys. Res. Commun. pmid:1550556
Wozniak M et al. Alternative farnesoid structures induce different conformational outcomes upon the Drosophila ortholog of the retinoid X receptor, ultraspiracle. 2004 Insect Biochem. Mol. Biol. pmid:15522611
Williams JM and Savage CO Characterization of the regulation and functional consequences of p21ras activation in neutrophils by antineutrophil cytoplasm antibodies. 2005 J. Am. Soc. Nephrol. pmid:15548565
Hogan DA et al. A Pseudomonas aeruginosa quorum-sensing molecule influences Candida albicans morphology. 2004 Mol. Microbiol. pmid:15554963
Lutz RJ et al. Nucleoplasmic localization of prelamin A: implications for prenylation-dependent lamin A assembly into the nuclear lamina. 1992 Proc. Natl. Acad. Sci. U.S.A. pmid:1557405
Yang SP and Raner GM Cytochrome P450 expression and activities in human tongue cells and their modulation by green tea extract. 2005 Toxicol. Appl. Pharmacol. pmid:15629189
Shearer AG and Hampton RY Lipid-mediated, reversible misfolding of a sterol-sensing domain protein. 2005 EMBO J. pmid:15635451
Havel CM and Watson JA Isopentenoid synthesis in isolated embryonic Drosophila cells: absolute, basal mevalonate synthesis rate determination. 1992 Arch. Biochem. Biophys. pmid:1567218
Cao YY et al. cDNA microarray analysis of differential gene expression in Candida albicans biofilm exposed to farnesol. 2005 Antimicrob. Agents Chemother. pmid:15673737
Blum R et al. Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death. 2005 Cancer Res. pmid:15705901
Hubálek F et al. Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors. 2005 J. Biol. Chem. pmid:15710600
Laffey SF and Butler G Phenotype switching affects biofilm formation by Candida parapsilosis. 2005 Microbiology (Reading, Engl.) pmid:15817776
Horn TL et al. Modulation of hepatic and renal drug metabolizing enzyme activities in rats by subchronic administration of farnesol. 2005 Chem. Biol. Interact. pmid:15840382
Frosch PJ et al. Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix. 2005 Contact Derm. pmid:15859993
Frosch PJ et al. Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products. 2005 Contact Derm. pmid:15859994
Katsuyama M et al. A novel method to control the balance of skin microflora. Part 1. Attack on biofilm of Staphylococcus aureus without antibiotics. 2005 J. Dermatol. Sci. pmid:15927813
Katsuyama M et al. A novel method to control the balance of skin microflora Part 2. A study to assess the effect of a cream containing farnesol and xylitol on atopic dry skin. 2005 J. Dermatol. Sci. pmid:15927814
Yue W et al. Farnesylthiosalicylic acid blocks mammalian target of rapamycin signaling in breast cancer cells. 2005 Int. J. Cancer pmid:15957161