LipidPedia

2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

Cross Reference

Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

MeSH term	MeSH ID	Detail
Lung Injury	D055370	14 associated lipids
Candidiasis, Invasive	D058365	2 associated lipids

MeSH term

Lung Injury

Candidiasis, Invasive

D058365

2 associated lipids

Per page 10 20 50 100 | Total 950

Authors	Title	Published	Journal	PubMed Link
Chen CK et al.	The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity.	2008	J. Biol. Inorg. Chem.	pmid:18392864
Ivanov SS et al.	Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins.	2010	J. Biol. Chem.	pmid:20813839
Gibbs JB et al.	Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo.	1993	J. Biol. Chem.	pmid:8463291
Kisselev O et al.	Efficient interaction with a receptor requires a specific type of prenyl group on the G protein gamma subunit.	1995	J. Biol. Chem.	pmid:7592699
Fujiyama A et al.	S-farnesylation and methyl esterification of C-terminal domain of yeast RAS2 protein prior to fatty acid acylation.	1991	J. Biol. Chem.	pmid:1917931
Maltese WA and Erdman RA	Characterization of isoprenoid involved in the post-translational modification of mammalian cell proteins.	1989	J. Biol. Chem.	pmid:2808372
Gonzalez-Pacanowska D et al.	Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation.	1988	J. Biol. Chem.	pmid:3335546
Bostedor RG et al.	Farnesol-derived dicarboxylic acids in the urine of animals treated with zaragozic acid A or with farnesol.	1997	J. Biol. Chem.	pmid:9083051
Koeppe JK et al.	A specific photoaffinity label for hemolymph and ovarian juvenile hormone-binding proteins in Leucophaea maderae.	1984	J. Biol. Chem.	pmid:6699014
McGuire TF et al.	Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation.	1996	J. Biol. Chem.	pmid:8910319
Rosado JA and Sage SO	Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets.	2001	J. Biol. Chem.	pmid:11278479
Wright MM et al.	Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis.	2001	J. Biol. Chem.	pmid:11306571
Daily D et al.	Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by dual activation of the ras-phosphoinositide 3-kinase and jun n-terminal kinase pathways.	2001	J. Biol. Chem.	pmid:11290748
Kisselev OG et al.	A farnesylated domain in the G protein gamma subunit is a specific determinant of receptor coupling.	1994	J. Biol. Chem.	pmid:8063769
LÃ¼bben M and Morand K	Novel prenylated hemes as cofactors of cytochrome oxidases. Archaea have modified hemes A and O.	1994	J. Biol. Chem.	pmid:8063781
Correll CC et al.	Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.	1994	J. Biol. Chem.	pmid:8021239
Cox AD et al.	The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation.	1994	J. Biol. Chem.	pmid:8034681
de Ropp JS and Troy FA	2H NMR investigation of the organization and dynamics of polyisoprenols in membranes.	1985	J. Biol. Chem.	pmid:4066690
Touhara K and Prestwich GD	Juvenile hormone epoxide hydrolase. Photoaffinity labeling, purification, and characterization from tobacco hornworm eggs.	1993	J. Biol. Chem.	pmid:8396141
Hartman HL et al.	Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium.	2004	J. Biol. Chem.	pmid:15131129

2E,6E-farnesol

Cross Reference

Introduction

What diseases are associated with 2E,6E-farnesol?

Related references are mostly published in these journals:

Possible diseases from mapped MeSH terms on references

PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Visualization in cellular structure

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What functions are associated with 2E,6E-farnesol?

Related references are published most in these journals:

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:

What common seen animal models are associated with 2E,6E-farnesol?

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

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