| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Injury | D055370 | 14 associated lipids |
| Candidiasis, Invasive | D058365 | 2 associated lipids |
2E,6E-farnesol
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
Cross Reference
Introduction
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2E,6E-farnesol?
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
PubChem Associated disorders and diseases
What pathways are associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2E,6E-farnesol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2E,6E-farnesol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2E,6E-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ivanov SS et al. | Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins. | 2010 | J. Biol. Chem. | pmid:20813839 |
| Newman CM et al. | Post-translational processing of Schizosaccharomyces pombe YPT proteins. | 1992 | J. Biol. Chem. | pmid:1597466 |
| Bradfute DL et al. | Squalene synthase-deficient mutant of Chinese hamster ovary cells. | 1992 | J. Biol. Chem. | pmid:1526971 |
| Gibbs JB et al. | Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. | 1993 | J. Biol. Chem. | pmid:8463291 |
| Kisselev O et al. | Efficient interaction with a receptor requires a specific type of prenyl group on the G protein gamma subunit. | 1995 | J. Biol. Chem. | pmid:7592699 |
| Keller RK et al. | Studies on the regulation of glycoprotein biosynthesis. An investigation of the rate-limiting steps of dolichyl phosphate biosynthesis. | 1979 | J. Biol. Chem. | pmid:489612 |
| Koeppe JK et al. | A specific photoaffinity label for hemolymph and ovarian juvenile hormone-binding proteins in Leucophaea maderae. | 1984 | J. Biol. Chem. | pmid:6699014 |
| Cornforth JW et al. | Studies on the biosynthesis of cholesterol. XX. Steric course of decarboxylation of 5-pyrophosphomevalonate and of the carbon to carbon bond formation in the biosynthesis of farnesyl pyrophosphate. | 1966 | J. Biol. Chem. | pmid:4288360 |
| Allen CM et al. | A long chain terpenyl pyrophosphate synthetase from Micrococcus lysodeikticus. | 1967 | J. Biol. Chem. | pmid:4290445 |
| Dorsey JK and Porter JW | The inhibition of mevalonic kinase by geranyl and farnesyl pyrophosphates. | 1968 | J. Biol. Chem. | pmid:4300840 |
| McGuire TF et al. | Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation. | 1996 | J. Biol. Chem. | pmid:8910319 |
| Onono F et al. | Efficient use of exogenous isoprenols for protein isoprenylation by MDA-MB-231 cells is regulated independently of the mevalonate pathway. | 2013 | J. Biol. Chem. | pmid:23908355 |
| Roullet JB et al. | Modulation of neuronal voltage-gated calcium channels by farnesol. | 1999 | J. Biol. Chem. | pmid:10464274 |
| Daily D et al. | Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by dual activation of the ras-phosphoinositide 3-kinase and jun n-terminal kinase pathways. | 2001 | J. Biol. Chem. | pmid:11290748 |
| Chakrabarti D et al. | Protein farnesyltransferase and protein prenylation in Plasmodium falciparum. | 2002 | J. Biol. Chem. | pmid:12194969 |
| Correll CC et al. | Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1994 | J. Biol. Chem. | pmid:8021239 |
| Cox AD et al. | The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation. | 1994 | J. Biol. Chem. | pmid:8034681 |
| de Ropp JS and Troy FA | 2H NMR investigation of the organization and dynamics of polyisoprenols in membranes. | 1985 | J. Biol. Chem. | pmid:4066690 |
| Touhara K and Prestwich GD | Juvenile hormone epoxide hydrolase. Photoaffinity labeling, purification, and characterization from tobacco hornworm eggs. | 1993 | J. Biol. Chem. | pmid:8396141 |
| Marom M et al. | Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid. | 1995 | J. Biol. Chem. | pmid:7673206 |