MeSH term | MeSH ID | Detail |
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Lung Injury | D055370 | 14 associated lipids |
Candidiasis, Invasive | D058365 | 2 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hanley K et al. | Fetal epidermal differentiation and barrier development In vivo is accelerated by nuclear hormone receptor activators. | 1999 | J. Invest. Dermatol. | pmid:10571735 |
Goodwin TE et al. | African elephant sesquiterpenes. | 1999 | J. Nat. Prod. | pmid:10579877 |
Machida K and Tanaka T | Farnesol-induced generation of reactive oxygen species dependent on mitochondrial transmembrane potential hyperpolarization mediated by F(0)F(1)-ATPase in yeast. | 1999 | FEBS Lett. | pmid:10580101 |
Elad G et al. | Targeting of K-Ras 4B by S-trans,trans-farnesyl thiosalicylic acid. | 1999 | Biochim. Biophys. Acta | pmid:10590312 |
Hirohata S et al. | Inhibition of human B cell activation by a novel nonsteroidal anti-inflammatory drug, indometacin famesil. | 1999 | Immunopharmacology | pmid:10598881 |
Reif S et al. | The Ras antagonist, farnesylthiosalicylic acid (FTS), inhibits experimentally-induced liver cirrhosis in rats. | 1999 | J. Hepatol. | pmid:10604579 |
Yang W et al. | Protein farnesylation is critical for maintaining normal cell morphology and canavanine resistance in Schizosaccharomyces pombe. | 2000 | J. Biol. Chem. | pmid:10617635 |
Jansen B et al. | Farnesylthiosalicylic acid inhibits the growth of human Merkel cell carcinoma in SCID mice. | 1999 | J. Mol. Med. | pmid:10619439 |
Girgert R et al. | Inhibition of farnesyl-protein-transferase in neuroblastoma cells by alpha-hydroxyfarnesylphosphonate. | 1999 Jul-Aug | Anticancer Res. | pmid:10652579 |
Yasugi E | [Induction of apoptosis by isoprenoids]. | 1999 | Seikagaku | pmid:10659677 |