MeSH term | MeSH ID | Detail |
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Arteriosclerosis | D001161 | 86 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kafri M et al. | Inhibition of Ras attenuates the course of experimental autoimmune neuritis. | 2005 | J. Neuroimmunol. | pmid:16154640 |
Crick DC et al. | Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells. | 1998 | J. Neurochem. | pmid:9603204 |
Chin PC et al. | The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism. | 2004 | J. Neurochem. | pmid:15255937 |
Wang X et al. | Waikialoid A suppresses hyphal morphogenesis and inhibits biofilm development in pathogenic Candida albicans. | 2012 | J. Nat. Prod. | pmid:22400916 |
Villegas LF et al. | (+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids. | 2001 | J. Nat. Prod. | pmid:11678668 |
Jones TH et al. | Farnesylamine from the ant Monomorium fieldi Forel. | 2003 | J. Nat. Prod. | pmid:12662086 |
Goodwin TE et al. | African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol. | 2002 | J. Nat. Prod. | pmid:12350155 |
Goodwin TE et al. | African elephant sesquiterpenes. | 1999 | J. Nat. Prod. | pmid:10579877 |
Li X et al. | New polyoxygenated farnesylcyclohexenones, deacetoxyyanuthone A and its hydro derivative from the marine-derived fungus Penicillium sp. | 2003 | J. Nat. Prod. | pmid:14640527 |
Jansen B et al. | Farnesylthiosalicylic acid inhibits the growth of human Merkel cell carcinoma in SCID mice. | 1999 | J. Mol. Med. | pmid:10619439 |
Ward SM et al. | TGFbeta regulates the expression of G alpha(i2) via an effect on the localization of ras. | 2002 | J. Mol. Cell. Cardiol. | pmid:12392895 |
Brilhante RS et al. | Histoplasma capsulatum in planktonic and biofilm forms: in vitro susceptibility to amphotericin B, itraconazole and farnesol. | 2015 | J. Med. Microbiol. | pmid:25657300 |
McAlester G et al. | Signal-mediated interactions between Pseudomonas aeruginosa and Candida albicans. | 2008 | J. Med. Microbiol. | pmid:18436588 |
Sharma RN and Saxena KN | Orientation and developmental inhibition in the housefly by certain terpenoids. | 1974 | J. Med. Entomol. | pmid:4281838 |
Prashad M et al. | N-(arylalkyl)farnesylamines: new potent squalene synthetase inhibitors. | 1993 | J. Med. Chem. | pmid:8496919 |
Ling Y et al. | Novel nitric oxide-releasing derivatives of farnesylthiosalicylic acid: synthesis and evaluation of antihepatocellular carcinoma activity. | 2011 | J. Med. Chem. | pmid:21504204 |
Grienke U et al. | Antiviral potential and molecular insight into neuraminidase inhibiting diarylheptanoids from Alpinia katsumadai. | 2010 | J. Med. Chem. | pmid:20014777 |
de Montellano PR et al. | Inhibition of squalene synthetase by farnesyl pyrophosphate analogues. | 1977 | J. Med. Chem. | pmid:189031 |
Gibbs BS et al. | Novel farnesol and geranylgeraniol analogues: A potential new class of anticancer agents directed against protein prenylation. | 1999 | J. Med. Chem. | pmid:10508429 |
Marciano D et al. | Farnesyl derivatives of rigid carboxylic acids-inhibitors of ras-dependent cell growth. | 1995 | J. Med. Chem. | pmid:7731012 |