MeSH term | MeSH ID | Detail |
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Candidiasis, Invasive | D058365 | 2 associated lipids |
Anisakiasis | D017129 | 2 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mann FM et al. | Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis. | 2011 | FEBS Lett. | pmid:21237161 |
Busch S and Unruh T | The influence of additives on the nanoscopic dynamics of the phospholipid dimyristoylphosphatidylcholine. | 2011 | Biochim. Biophys. Acta | pmid:21036141 |
Shareck J and Belhumeur P | Modulation of morphogenesis in Candida albicans by various small molecules. | 2011 | Eukaryotic Cell | pmid:21642508 |
Yang L et al. | ZL11n is a novel nitric oxide-releasing derivative of farnesylthiosalicylic acid that induces apoptosis in human hepatoma HepG2 cells via MAPK/mitochondrial pathways. | 2011 | Biochem. Biophys. Res. Commun. | pmid:21621522 |
Barkan B et al. | Phenotypic reversion of invasive neurofibromin-deficient schwannoma by FTS: Ras inhibition reduces BMP4/Erk/Smad signaling. | 2011 | Mol. Cancer Ther. | pmid:21632464 |
Yoo S et al. | Antimicrobial traits of tea- and cranberry-derived polyphenols against Streptococcus mutans. | 2011 | Caries Res. | pmid:21720161 |
Fitzpatrick AH et al. | Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis. | 2011 | Plant J. | pmid:21395888 |
Nevo Y et al. | The Ras antagonist, farnesylthiosalicylic acid (FTS), decreases fibrosis and improves muscle strength in dy/dy mouse model of muscular dystrophy. | 2011 | PLoS ONE | pmid:21445359 |
Khan R and Sultana S | Farnesol attenuates 1,2-dimethylhydrazine induced oxidative stress, inflammation and apoptotic responses in the colon of Wistar rats. | 2011 | Chem. Biol. Interact. | pmid:21453689 |
Zhang L et al. | Bisbibenzyls, a new type of antifungal agent, inhibit morphogenesis switch and biofilm formation through upregulation of DPP3 in Candida albicans. | 2011 | PLoS ONE | pmid:22174935 |
Hall RA et al. | The quorum-sensing molecules farnesol/homoserine lactone and dodecanol operate via distinct modes of action in Candida albicans. | 2011 | Eukaryotic Cell | pmid:21666074 |
Biran A et al. | Downregulation of survivin and aurora A by histone deacetylase and RAS inhibitors: a new drug combination for cancer therapy. | 2011 | Int. J. Cancer | pmid:20473860 |
Fong C et al. | Monodisperse nonionic isoprenoid-type hexahydrofarnesyl ethylene oxide surfactants: high throughput lyotropic liquid crystalline phase determination. | 2011 | Langmuir | pmid:21294552 |
Kraitzer A et al. | Composite fiber structures with antiproliferative agents exhibit advantageous drug delivery and cell growth inhibition in vitro. | 2011 | J Pharm Sci | pmid:20623695 |
Mor A et al. | Ras inhibition induces insulin sensitivity and glucose uptake. | 2011 | PLoS ONE | pmid:21738773 |
Sharma M and Prasad R | The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans. | 2011 | Antimicrob. Agents Chemother. | pmid:21768514 |
Nishimori R et al. | Biosynthesis of unnatural bacteriochlorophyll c derivatives esterified with α,ω-diols in the green sulfur photosynthetic bacterium Chlorobaculum tepidum. | 2011 | Biochemistry | pmid:21846125 |
Riely GJ et al. | A phase II trial of Salirasib in patients with lung adenocarcinomas with KRAS mutations. | 2011 | J Thorac Oncol | pmid:21847063 |
Ganguly S et al. | Zap1 control of cell-cell signaling in Candida albicans biofilms. | 2011 | Eukaryotic Cell | pmid:21890817 |
Dinamarco TM et al. | Farnesol-induced cell death in the filamentous fungus Aspergillus nidulans. | 2011 | Biochem. Soc. Trans. | pmid:21936849 |