MeSH term | MeSH ID | Detail |
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Candidiasis, Invasive | D058365 | 2 associated lipids |
Anisakiasis | D017129 | 2 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Boisvenue RJ et al. | Haemonchus contortus: effects of compounds with juvenile hormone activity on the in vitro development of infective larvae. | 1977 | Exp. Parasitol. | pmid:862711 |
Meigs TE et al. | Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo. | 1996 | J. Biol. Chem. | pmid:8626470 |
O'Brien ML et al. | Convergence of three steroid receptor pathways in the mediation of nongenotoxic hepatocarcinogenesis. | 1996 | Carcinogenesis | pmid:8625436 |
Parmryd I et al. | Identification of spinach farnesyl protein transferase. Dithiothreitol as an acceptor in vitro. | 1995 | Eur. J. Biochem. | pmid:8575428 |
Tachibana A et al. | Evidence for farnesol-mediated isoprenoid synthesis regulation in a halophilic archaeon, Haloferax volcanii. | 1996 | FEBS Lett. | pmid:8566226 |
Prashad M et al. | N-(arylalkyl)farnesylamines: new potent squalene synthetase inhibitors. | 1993 | J. Med. Chem. | pmid:8496919 |
Gibbs JB et al. | Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. | 1993 | J. Biol. Chem. | pmid:8463291 |
O'Donnell MP et al. | Lovastatin inhibits proliferation of rat mesangial cells. | 1993 | J. Clin. Invest. | pmid:8423236 |
Touhara K and Prestwich GD | Juvenile hormone epoxide hydrolase. Photoaffinity labeling, purification, and characterization from tobacco hornworm eggs. | 1993 | J. Biol. Chem. | pmid:8396141 |
Akopyan TN et al. | Proteolytic processing of farnesylated peptides: assay and partial purification from pig brain membranes of an endopeptidase which has the characteristics of E.C. 3.4.24.15. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8297391 |