MeSH term | MeSH ID | Detail |
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Candidiasis, Invasive | D058365 | 2 associated lipids |
Anisakiasis | D017129 | 2 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bradfute DL et al. | Squalene synthase-deficient mutant of Chinese hamster ovary cells. | 1992 | J. Biol. Chem. | pmid:1526971 |
Reif S et al. | Treatment of thioacetamide-induced liver cirrhosis by the Ras antagonist, farnesylthiosalicylic acid. | 2004 | J. Hepatol. | pmid:15288472 |
Kruppa M et al. | The two-component signal transduction protein Chk1p regulates quorum sensing in Candida albicans. | 2004 | Eukaryotic Cell | pmid:15302838 |
Staines AG et al. | Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1. | 2004 | Biochem. J. | pmid:15320866 |
Inoue Y et al. | The antibacterial effects of terpene alcohols on Staphylococcus aureus and their mode of action. | 2004 | FEMS Microbiol. Lett. | pmid:15321680 |
Bai M and Prestwich GD | Inhibition and activation of porcine squalene epoxidase. | 1992 | Arch. Biochem. Biophys. | pmid:1536566 |
Fukuda S and Pelus LM | Activated H-Ras regulates hematopoietic cell survival by modulating Survivin. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15369798 |
Chen AP et al. | Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase. | 2005 | Biochem. J. | pmid:15447632 |
McMahon LP et al. | Farnesylthiosalicylic acid inhibits mammalian target of rapamycin (mTOR) activity both in cells and in vitro by promoting dissociation of the mTOR-raptor complex. | 2005 | Mol. Endocrinol. | pmid:15459249 |
Downie MM et al. | Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro. | 2004 | Br. J. Dermatol. | pmid:15491415 |