MeSH term | MeSH ID | Detail |
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Candidiasis, Invasive | D058365 | 2 associated lipids |
Anisakiasis | D017129 | 2 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cugini C et al. | Candida albicans-produced farnesol stimulates Pseudomonas quinolone signal production in LasR-defective Pseudomonas aeruginosa strains. | 2010 | Microbiology (Reading, Engl.) | pmid:20656785 |
Machida K et al. | Farnesol-induced growth inhibition in Saccharomyces cerevisiae by a cell cycle mechanism. | 1999 | Microbiology (Reading, Engl.) | pmid:10075411 |
Laffey SF and Butler G | Phenotype switching affects biofilm formation by Candida parapsilosis. | 2005 | Microbiology (Reading, Engl.) | pmid:15817776 |
Hisajima T et al. | Protective effects of farnesol against oral candidiasis in mice. | 2008 | Microbiol. Immunol. | pmid:18667031 |
Abe S et al. | Suppression of anti-Candida activity of macrophages by a quorum-sensing molecule, farnesol, through induction of oxidative stress. | 2009 | Microbiol. Immunol. | pmid:19493200 |
Deveau A and Hogan DA | Linking quorum sensing regulation and biofilm formation by Candida albicans. | 2011 | Methods Mol. Biol. | pmid:21031315 |
Andres DA et al. | Rapid identification of cysteine-linked isoprenyl groups by metabolic labeling with [3H]farnesol and [3H]geranylgeraniol. | 1999 | Methods Mol. Biol. | pmid:10399149 |
Dudler T and Gelb MH | Probing the role of H-Ras lipidation for signaling functions in Xenopus laevis oocytes. | 1999 | Methods Mol. Biol. | pmid:10399152 |
Corsini A et al. | Incorporation of radiolabeled prenyl alcohols and their analogs into mammalian cell proteins. A useful tool for studying protein prenylation. | 1999 | Methods Mol. Biol. | pmid:10399150 |
Berzat AC et al. | Using inhibitors of prenylation to block localization and transforming activity. | 2006 | Meth. Enzymol. | pmid:16757354 |