MeSH term | MeSH ID | Detail |
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Candidiasis, Invasive | D058365 | 2 associated lipids |
Anisakiasis | D017129 | 2 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yu JS et al. | Synthesis of farnesol isomers via a modified Wittig procedure. | 2005 | Org. Lett. | pmid:16235893 |
Navarathna DH et al. | Enhanced pathogenicity of Candida albicans pre-treated with subinhibitory concentrations of fluconazole in a mouse model of disseminated candidiasis. | 2005 | J. Antimicrob. Chemother. | pmid:16239285 |
Amos S et al. | Farnesylthiosalicylic acid induces caspase activation and apoptosis in glioblastoma cells. | 2006 | Cell Death Differ. | pmid:16239932 |
Koo H et al. | Apigenin and tt-farnesol with fluoride effects on S. mutans biofilms and dental caries. | 2005 | J. Dent. Res. | pmid:16246933 |
Ferri N et al. | Isothiazole dioxide derivative 6n inhibits vascular smooth muscle cell proliferation and protein farnesylation. | 2005 | Biochem. Pharmacol. | pmid:16257390 |
Rüegg T et al. | 3-Farnesyl-2-hydroxybenzoic acid is a new anti-Helicobacter pylori compound from Piper multiplinervium. | 2006 | J Ethnopharmacol | pmid:16266794 |
Hemmerlin A et al. | Monitoring farnesol-induced toxicity in tobacco BY-2 cells with a fluorescent analog. | 2006 | Arch. Biochem. Biophys. | pmid:16307722 |
Ma YT and Rando RR | A microsomal endoprotease that specifically cleaves isoprenylated peptides. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1631119 |
Kato K et al. | Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1631135 |
Santen RJ et al. | Farnesylthiosalicylic acid: inhibition of proliferation and enhancement of apoptosis of hormone-dependent breast cancer cells. | 2006 | Anticancer Drugs | pmid:16317288 |