MeSH term | MeSH ID | Detail |
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Candidiasis, Invasive | D058365 | 2 associated lipids |
Anisakiasis | D017129 | 2 associated lipids |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cheng QF et al. | Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens. | 2001 | Exp. Eye Res. | pmid:11446774 |
Nah J et al. | Partial characterization of farnesyl and geranylgeranyl diphosphatases induced in rice seedlings by UV-C irradiation. | 2001 | Plant Cell Physiol. | pmid:11522913 |
Rakhit RD et al. | Role of G proteins and modulation of p38 MAPK activation in the protection by nitric oxide against ischemia-reoxygenation injury. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11527399 |
Mizukami Y et al. | Requirement of c-jun N-terminal kinase for apoptotic cell death induced by farnesyltransferase inhibitor, farnesylamine, in human pancreatic cancer cells. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11594773 |
Villegas LF et al. | (+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids. | 2001 | J. Nat. Prod. | pmid:11678668 |
Karussis D et al. | The Ras-pathway inhibitor, S-trans-trans-farnesylthiosalicylic acid, suppresses experimental allergic encephalomyelitis. | 2001 | J. Neuroimmunol. | pmid:11694313 |
Kim SY et al. | Inhibition effect of new farnesol derivatives on all-trans-retinoic acid metabolism. | 2001 | Metab. Clin. Exp. | pmid:11699057 |
Cantrell CL et al. | Antimycobacterial plant terpenoids. | 2001 | Planta Med. | pmid:11731906 |
Sari R et al. | Impairment by lovastatin of neural relaxation of the rabbit sphincter of Oddi. | 2001 | Eur. J. Pharmacol. | pmid:11734192 |
Katzav A et al. | Treatment of MRL/lpr mice, a genetic autoimmune model, with the Ras inhibitor, farnesylthiosalicylate (FTS). | 2001 | Clin. Exp. Immunol. | pmid:11737078 |
Inoue I et al. | Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11779144 |
Gana-Weisz M et al. | The Ras inhibitor S-trans,trans-farnesylthiosalicylic acid chemosensitizes human tumor cells without causing resistance. | 2002 | Clin. Cancer Res. | pmid:11839677 |
Mizukami Y | [Oleylamine (long-chain fatty amine)-induced cell death through MAP kinase pathways in human pancreatic cancer cells]. | 2002 | Hokkaido Igaku Zasshi | pmid:11868368 |
Radetich B and Corey EJ | A general stereocontrolled, convergent synthesis of oligoprenols that parallels the biosynthetic pathway. | 2002 | J. Am. Chem. Soc. | pmid:11890779 |
Teal PE | Effects of allatotropin and allatostatin on in vitro production of juvenile hormones by the corpora allata of virgin females of the moths of Heliothis virescens and Manduca sexta. | 2002 | Peptides | pmid:11897385 |
Ownby SE and Hohl RJ | Farnesol and geranylgeraniol: prevention and reversion of lovastatin-induced effects in NIH3T3 cells. | 2002 | Lipids | pmid:11908910 |
Smalley KS and Eisen TG | Farnesyl thiosalicylic acid inhibits the growth of melanoma cells through a combination of cytostatic and pro-apoptotic effects. | 2002 | Int. J. Cancer | pmid:11920610 |
Hamada M et al. | Farnesylpyridinium, an analog of isoprenoid farnesol, induces apoptosis but suppresses apoptotic body formation in human promyelocytic leukemia cells. | 2002 | FEBS Lett. | pmid:11943160 |
Takahashi N et al. | Dual action of isoprenols from herbal medicines on both PPARgamma and PPARalpha in 3T3-L1 adipocytes and HepG2 hepatocytes. | 2002 | FEBS Lett. | pmid:11943173 |
Kim S et al. | Evaluation of morphogenic regulatory activity of farnesoic acid and its derivatives against Candida albicans dimorphism. | 2002 | Bioorg. Med. Chem. Lett. | pmid:11958988 |