2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Candidiasis, Invasive D058365 2 associated lipids
Anisakiasis D017129 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

Download all related citations
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Authors Title Published Journal PubMed Link
Hartmann MA et al. Metabolism of farnesyl diphosphate in tobacco BY-2 cells treated with squalestatin. 2000 Biochem. Soc. Trans. pmid:11171211
Schlitzer M and Dahse HM Structure activity relationship of antiproliferative N-acyl-beta-alanine amides. 2000 Nov-Dec Anticancer Res. pmid:11205283
Hanley K et al. Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D. 2001 J. Lipid Res. pmid:11254751
Fayard E et al. Xol INXS: role of the liver X and the farnesol X receptors. 2001 Curr. Opin. Lipidol. pmid:11264982
Rosado JA and Sage SO Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets. 2001 J. Biol. Chem. pmid:11278479
Daily D et al. Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by dual activation of the ras-phosphoinositide 3-kinase and jun n-terminal kinase pathways. 2001 J. Biol. Chem. pmid:11290748
Clausen VA et al. Stereochemical analysis of the reaction catalyzed by human protein geranylgeranyl transferase. 2001 Biochemistry pmid:11300771
Wright MM et al. Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis. 2001 J. Biol. Chem. pmid:11306571
McCaffery AR and Highnam KC Effects of corpus aliatum hormone and its mimics on the activity of the cerebral neurosecretory system of Locusta migratoria migratorioides R. & F. 1975 Gen. Comp. Endocrinol. pmid:1132652
Hornby JM et al. Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol. 2001 Appl. Environ. Microbiol. pmid:11425711