2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Anisakiasis D017129 2 associated lipids
Candidiasis, Invasive D058365 2 associated lipids
Neuritis, Autoimmune, Experimental D009444 4 associated lipids
Nerve Sheath Neoplasms D018317 4 associated lipids
Head Injuries, Closed D016489 5 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Neurilemmoma D009442 10 associated lipids
Meningioma D008579 11 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Neoplasms, Glandular and Epithelial D009375 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

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Authors Title Published Journal PubMed Link
Yu LH et al. Possible inhibitory molecular mechanism of farnesol on the development of fluconazole resistance in Candida albicans biofilm. 2012 Antimicrob. Agents Chemother. pmid:22106223
Brilhante RS et al. Sesquiterpene farnesol contributes to increased susceptibility to β-lactams in strains of Burkholderia pseudomallei. 2012 Antimicrob. Agents Chemother. pmid:22290941
Stoddart CA et al. Oral administration of the nucleoside EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine) provides rapid suppression of HIV viremia in humanized mice and favorable pharmacokinetic properties in mice and the rhesus macaque. 2015 Antimicrob. Agents Chemother. pmid:25941222
Rossignol T et al. Transcriptional response of Candida parapsilosis following exposure to farnesol. 2007 Antimicrob. Agents Chemother. pmid:17684006
Hornby JM et al. Farnesol biosynthesis in Candida albicans: cellular response to sterol inhibition by zaragozic acid B. 2003 Antimicrob. Agents Chemother. pmid:12821501
Cao YY et al. cDNA microarray analysis of differential gene expression in Candida albicans biofilm exposed to farnesol. 2005 Antimicrob. Agents Chemother. pmid:15673737
Jabra-Rizk MA et al. Effect of farnesol on Staphylococcus aureus biofilm formation and antimicrobial susceptibility. 2006 Antimicrob. Agents Chemother. pmid:16569866
Dumitru R et al. Defined anaerobic growth medium for studying Candida albicans basic biology and resistance to eight antifungal drugs. 2004 Antimicrob. Agents Chemother. pmid:15215080
Rodrigues Goulart H et al. Terpenes arrest parasite development and inhibit biosynthesis of isoprenoids in Plasmodium falciparum. 2004 Antimicrob. Agents Chemother. pmid:15215101
Hornby JM and Nickerson KW Enhanced production of farnesol by Candida albicans treated with four azoles. 2004 Antimicrob. Agents Chemother. pmid:15155241