2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

Cross Reference

Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Glioma D005910 112 associated lipids
Insulin Resistance D007333 99 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

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Authors Title Published Journal PubMed Link
Keenan MV and Allen CM Characterization of undecaprenyl pyrophosphate synthetase from Lactobacillus plantarum. 1974 Arch. Biochem. Biophys. pmid:4599964
Dugan RE and Porter JW Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction. 1972 Arch. Biochem. Biophys. pmid:4403691
Jungalwala FB and Porter JW Biosynthesis of phytoene from isopentenyl and farnesyl pyrophosphates by a partially purified tomato enzyme system. 1967 Arch. Biochem. Biophys. pmid:4293186
Benedict CR et al. Properties of farnesyl pyrophosphate synthetase of pig liver. 1965 Arch. Biochem. Biophys. pmid:4284635
Krishna G et al. Enzymic conversion of farnesyl pyrophosphate to squalene. 1966 Arch. Biochem. Biophys. pmid:4380977
Desrosiers RR and Béliveau R Regulation by GTPgammaS of protein carboxylmethyltransferase activity in kidney brush border membranes. 1998 Arch. Biochem. Biophys. pmid:9514644
Baba T et al. Dehydrodolichyl diphosphate synthetase from rat seminiferous tubules. 1987 Arch. Biochem. Biophys. pmid:3813545
Xu L and Simoni RD The inhibition of degradation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase by sterol regulatory element binding protein cleavage-activating protein requires four phenylalanine residues in span 6 of HMG-CoA reductase transmembrane domain. 2003 Arch. Biochem. Biophys. pmid:12781775
Keller RK et al. Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver. 1996 Arch. Biochem. Biophys. pmid:8645011
Andres DA et al. Expression cloning of a novel farnesylated protein, RDJ2, encoding a DnaJ protein homologue. 1997 Arch. Biochem. Biophys. pmid:9328291