2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

Cross Reference

Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Arteriosclerosis D001161 86 associated lipids
Body Weight D001835 333 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Dermatomycoses D003881 17 associated lipids
Edema D004487 152 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Fibrosis D005355 23 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

Download all related citations
Per page 10 20 50 100 | Total 950
Authors Title Published Journal PubMed Link
Teal PE Effects of allatotropin and allatostatin on in vitro production of juvenile hormones by the corpora allata of virgin females of the moths of Heliothis virescens and Manduca sexta. 2002 Peptides pmid:11897385
Pammi M et al. Farnesol decreases biofilms of Staphylococcus epidermidis and exhibits synergy with nafcillin and vancomycin. 2011 Pediatr. Res. pmid:21857375
Marcuzzi A et al. Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency. 2008 Pediatr. Res. pmid:18391837
Ershova LS et al. [The action of a juvenile hormone synthetic analog--ether-farnesol on Xenopsylla cheopis fleas]. 1989 Sep-Oct Parazitologia pmid:2616197
Toró A et al. Transannular Diels-Alder studies on the asymmetric total synthesis of chatancin: the pyranophane approach. 2000 Org. Lett. pmid:10964353
Yu JS et al. Synthesis of farnesol isomers via a modified Wittig procedure. 2005 Org. Lett. pmid:16235893
Rudi A et al. Likonides A and B: new ansa farnesyl quinols from the marine sponge Hyatella sp. 2004 Org. Lett. pmid:15496087
Jin Y and Qiu FG A convergent stereocontrolled total synthesis of (-)-terpestacin. 2012 Org. Biomol. Chem. pmid:22710980
Koo H et al. Effects of apigenin and tt-farnesol on glucosyltransferase activity, biofilm viability and caries development in rats. 2002 Oral Microbiol. Immunol. pmid:12485324
Aizman E et al. Ras inhibition by FTS attenuates brain tumor growth in mice by direct antitumor activity and enhanced reactivity of cytotoxic lymphocytes. 2012 Oncotarget pmid:22323550
Mashiach-Farkash E et al. Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton. 2012 Oncotarget pmid:22776759
Schmukler E et al. Ras inhibition enhances autophagy, which partially protects cells from death. 2013 Oncotarget pmid:23847721
Schmukler E et al. Ras inhibition enhances autophagy, which partially protects cells from death. 2013 Oncotarget pmid:23370967
Barkan B et al. Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis. 2013 Oncotarget pmid:23530091
Faigenbaum R et al. Growth of poorly differentiated endometrial carcinoma is inhibited by combined action of medroxyprogesterone acetate and the Ras inhibitor Salirasib. 2013 Oncotarget pmid:23530112
Cheng HL et al. Zoledronate blocks geranylgeranylation not farnesylation to suppress human osteosarcoma U2OS cells metastasis by EMT via Rho A activation and FAK-inhibited JNK and p38 pathways. 2016 Oncotarget pmid:26848867
Hameiri-Grossman M et al. The association between let-7, RAS and HIF-1α in Ewing Sarcoma tumor growth. 2015 Oncotarget pmid:26393682
Goldshmit Y et al. Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma. 2014 Oncotarget pmid:25261371
Schmukler E et al. Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death. 2014 Oncotarget pmid:24368422
Weisz B et al. A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice. 1999 Oncogene pmid:10353601