2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Candidiasis, Invasive D058365 2 associated lipids
Lung Injury D055370 14 associated lipids
Nerve Sheath Neoplasms D018317 4 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Anisakiasis D017129 2 associated lipids
Head Injuries, Closed D016489 5 associated lipids
HIV Infections D015658 20 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Osteosarcoma D012516 50 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

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Authors Title Published Journal PubMed Link
Gilpin S and Maibach H Allergic contact dermatitis caused by farnesol: clinical relevance. 2010 Cutan Ocul Toxicol pmid:20858058
Charette N et al. Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition. 2010 Mol. Cancer pmid:20860815
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Kubesová A et al. Separation of attogram terpenes by the capillary zone electrophoresis with fluorometric detection. 2010 J Chromatogr A pmid:20933239
Bhagatji P et al. Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane. 2010 Biophys. J. pmid:21081081
Bhandari J et al. Identification of a novel abscisic acid-regulated farnesol dehydrogenase from Arabidopsis. 2010 Plant Physiol. pmid:20807998
Jin J et al. Farnesol, a potential efflux pump inhibitor in Mycobacterium smegmatis. 2010 Molecules pmid:21042264
Tsimberidou AM et al. Phase 1 first-in-human clinical study of S-trans,trans-farnesylthiosalicylic acid (salirasib) in patients with solid tumors. 2010 Cancer Chemother. Pharmacol. pmid:19484470
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Shimomura K et al. 2,3-Dihydrohomofarnesal: female sex attractant pheromone component of Callosobruchus rhodesianus (Pic). 2010 J. Chem. Ecol. pmid:20607368
Gregus P et al. Ultra high performance liquid chromatography tandem mass spectrometry analysis of quorum-sensing molecules of Candida albicans. 2010 J Pharm Biomed Anal pmid:20580513
Ghosh S et al. Candida albicans cell wall components and farnesol stimulate the expression of both inflammatory and regulatory cytokines in the murine RAW264.7 macrophage cell line. 2010 FEMS Immunol. Med. Microbiol. pmid:20618847
Dinamarco TM et al. The roles played by Aspergillus nidulans apoptosis-inducing factor (AIF)-like mitochondrial oxidoreductase (AifA) and NADH-ubiquinone oxidoreductases (NdeA-B and NdiA) in farnesol resistance. 2010 Fungal Genet. Biol. pmid:20654725
Cugini C et al. Candida albicans-produced farnesol stimulates Pseudomonas quinolone signal production in LasR-defective Pseudomonas aeruginosa strains. 2010 Microbiology (Reading, Engl.) pmid:20656785
Weber K et al. The quorum-sensing molecule E,E-farnesol--its variable secretion and its impact on the growth and metabolism of Candida species. 2010 Yeast pmid:20641010
Bustinza-Linares E et al. Salirasib in the treatment of pancreatic cancer. 2010 Future Oncol pmid:20528225
Deveau A et al. Farnesol induces hydrogen peroxide resistance in Candida albicans yeast by inhibiting the Ras-cyclic AMP signaling pathway. 2010 Eukaryotic Cell pmid:20118211
Moya M et al. Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile. 2010 Chem. Biol. Interact. pmid:20079722
Chagas CE et al. Farnesol inhibits cell proliferation and induces apoptosis after partial hepatectomy in rats. 2009 Sep-Oct Acta Cir Bras pmid:19851690