2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Arteriosclerosis D001161 86 associated lipids
Body Weight D001835 333 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Dermatomycoses D003881 17 associated lipids
Edema D004487 152 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Fibrosis D005355 23 associated lipids
Glioblastoma D005909 27 associated lipids
Glioma D005910 112 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Insulin Resistance D007333 99 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

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Authors Title Published Journal PubMed Link
Gough DP and Hemming FW The characterization and stereochemistry of biosynthesis of dolichols in rat liver. 1970 Biochem. J. pmid:4319540
Flint AP The activity and kinetic properties of mevalonate kinase in superovulated rat ovary. 1970 Biochem. J. pmid:4321929
Dialameh GH et al. Enzymatic alkylation of menaquinone-o to menaquinones microsomes from chick liver. 1970 Biochim. Biophys. Acta pmid:4323518
Castelli A et al. Effect of hydroxy analogs of coenzyme Q on DPNH- and succin-oxidase activities of yeast mitochondria. 1971 Biochem. Biophys. Res. Commun. pmid:4324835
George-Nascimento C et al. Non enzymic formation of nerolidol from farnesyl pyrophosphate in the presence of bivalent cations. 1971 Biochem. Biophys. Res. Commun. pmid:4334520
Kurokawa T et al. Formation of polyprenyl phosphates by a cell-free enzyme of Micrococcus lysodeikticus. 1971 Biochem. Biophys. Res. Commun. pmid:4334524
Slakey LL et al. The effects of fasting, refeeding, and time of day on the levels of enzymes effecting the conversion of -hydroxy- -methylglutaryl-coenzyme A to squalene. 1972 J. Biol. Chem. pmid:4337504
Polito A et al. Artificial substrates in squalene and sterol biosynthesis. 1972 J. Biol. Chem. pmid:4337856
Stone KJ and Strominger JL Inhibition of sterol biosynthesis by bacitracin. 1972 Proc. Natl. Acad. Sci. U.S.A. pmid:4338587
Warren CD and Jeanloz RW Chemical synthesis of pyrophosphodiesters of carbohydrates and isoprenoid alcohols. Lipid intermediates of bacterial cell wall and antigenic polysaccharide biosynthesis. 1972 Biochemistry pmid:4339875
Qureshi AA et al. Squalene synthetase. I. Dissociation and reassociation of enzyme complex. 1972 Biochem. Biophys. Res. Commun. pmid:4341049
Heintz R et al. Plant sterol metabolism. Demonstration and identification of a biosynthetic intermediate between farnesyl PP and squalene in a higher plant. 1972 Biochem. Biophys. Res. Commun. pmid:4344813
Qureshi AA et al. Squalene synthetase. II. Purification and properties of bakers' yeast enzyme. 1973 J. Biol. Chem. pmid:4348552
Beytia E et al. Squalene synthetase. 3. Mechanism of the reaction. 1973 J. Biol. Chem. pmid:4348553
Slakey LL et al. Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta. 1973 J. Lipid Res. pmid:4351784
Derksen A and Cohen P Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro. 1973 J. Biol. Chem. pmid:4355579
Ellsworth RK and Nowak CA A gas chromatographic-mass spectrometric analysis of the esterifying alcohols of pumpkin seed protochlorophylls. 1974 Anal. Biochem. pmid:4362215
Samuel O et al. Preparation of (1-3H) polyprenyl pyrophosphates. 1974 Biochimie pmid:4375498
Donninger C and Popják G Studies on the biosynthesis of cholesterol. 18. The stereospecificity of mevaldate reductase and the biosynthesis of asymmetrically labelled farnesyl pyrophosphate. 1966 Proc. R. Soc. Lond., B, Biol. Sci. pmid:4379290
Krishna G et al. Enzymic conversion of farnesyl pyrophosphate to squalene. 1966 Arch. Biochem. Biophys. pmid:4380977
Graebe JE Isoprenoid biosynthesis in a cell-free system from pea shoots. 1967 Science pmid:4381746
Nair KK Susceptibility of mosquito larvae to a synthetic juvenile hormone, farnesyl diethylamine. 1967 Naturwissenschaften pmid:4384815
Etemadi AH et al. Assay of the possible organization of particle-bound enzymes with squalene synthetase and squalene oxidocyclase systems. 1969 Biochem. J. pmid:4388240
Popják G et al. Biosynthesis and structure of a new intermediate between farnesyl pyrophosphate and squalene. 1969 J. Biol. Chem. pmid:4388617
Hintze-Podufal C The juvenile hormone-like effect of farnesol derivatives on the pupal development of Cerura vinula L. 1971 Z. Naturforsch. B pmid:4396584
Edmond J et al. Presqualene alcohol. Further evidence on the structure of a C 30 precursor of squalene. 1971 J. Biol. Chem. pmid:4399596
Rilling HC The effect of sterol carrier protein on squalene synthesis. 1972 Biochem. Biophys. Res. Commun. pmid:4400440
Metzler M et al. On the biosynthesis of juvenile hormone in the adult Cecropia moth. 1971 Z. Naturforsch. B pmid:4401880
Beedle AS et al. The stereochemistry of hydrogen transfer from NADPH catalysed by 3-hydroxy-3-methylglutaryl-coenzyme A reductase from rat liver. 1972 Eur. J. Biochem. pmid:4403574
Dugan RE and Porter JW Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction. 1972 Arch. Biochem. Biophys. pmid:4403691
Walton MJ and Pennock JF Some studies on the biosynthesis of ubiguinone, isoprenoid alcohols, squalene and sterols by marine invertebrates. 1972 Biochem. J. pmid:4403925
Qureshi AA et al. Lycopersene and prelycopersene pyrophosphate. Intermediates in carotene biosynthesis. 1972 J. Biol. Chem. pmid:4403969
Beedle AS et al. The stereochemistry of the reduction of mevaldic acid-coenzyme A hemithioacetal by rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. 1972 FEBS Lett. pmid:4405222
Binet L et al. [Farnesol, psychosedative and spasmolytic drug]. 1972 Sep-Oct Therapie pmid:4405589
Lanzrein B Influence of a juvenile hormone analogue on vitellogenin synthesis and oögenesis in larvae of Nauphoeta cinerea. 1974 J. Insect Physiol. pmid:4413859
Imai K et al. Letter: Derivation of (plus)- and (minus)-C17-juvenile hormone from its racemic alcohol derivative via fungal metabolism. 1974 J. Am. Chem. Soc. pmid:4414179
Shechter I Phosphate transfer from trans-farnesyl triphosphate to AMP in Gibberella fujikuroi. 1974 Biochim. Biophys. Acta pmid:4423368
Morozova NP et al. [The effect of a controlled gas atmosphere on farnesene dynamics and the development of sunburn in apples]. 1974 Jul-Aug Prikl. Biokhim. Mikrobiol. pmid:4453546
Tobe SS and Pratt GE The influence of substrate concentrations on the rate of insect juvenile hormone biosynthesis by corpora allata of the desert locust in vitro. 1974 Biochem. J. pmid:4462567
Overton KH and Roberts FM Biosynthesis of trans, trans- and cis, trans-farnesols by soluble enzymes from tissue cultures of Andrographis paniculata. 1974 Biochem. J. pmid:4468823
Levinson HZ [The evolution and biosynthesis of the terpinoid pheromones and hormones]. 1972 Naturwissenschaften pmid:4571813
Langman MJ et al. Treatment of chronic gastric ulcer with carbenoxolone and gefarnate: a comparative trial. 1973 Br Med J pmid:4577839
Newman CR and Montgomery DA A double-blind trial of oral gefarnate in duodenal ulcer. 1973 Br J Clin Pract pmid:4580209
Keenan MV and Allen CM Characterization of undecaprenyl pyrophosphate synthetase from Lactobacillus plantarum. 1974 Arch. Biochem. Biophys. pmid:4599964
Smith PM et al. Proceedings: A double blind trial of carbenoxolone and geranyl farnesylacetate in gastric ulcer. 1974 Gut pmid:4611753
Brockmann H and Knobloch G [A new bacteriochlorophyll from Rhodospirillum rubrum]. 1972 Arch Mikrobiol pmid:4627398
Madhavan K et al. Farnesol metabolism in Drosophila melanogaster: ontogeny and tissue distribution of octanol dehydrogenase and aldehyde oxidase. 1973 J. Insect Physiol. pmid:4631837
Richards JB and Hemming FW Dolichols, ubiquinones, geranylgeraniol and farnesol as the major metabolites of mevalonate in Phytophthora cactorum. 1972 Biochem. J. pmid:4643705
Akisue G [Secretion of Myroxylon peruiforum L.f. 3. Physical and chemical characterization of essential oil from balsam and qualitative analysis of various componets]. 1972 Jul-Dec Rev Farm Bioquim Univ Sao Paulo pmid:4664898
Canonica L et al. Biosynthesis of mycophenolic acid. 1972 J. Chem. Soc. Perkin Trans. I pmid:4674609