2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Arteriosclerosis D001161 86 associated lipids
Body Weight D001835 333 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Dermatomycoses D003881 17 associated lipids
Edema D004487 152 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Fibrosis D005355 23 associated lipids
Glioblastoma D005909 27 associated lipids
Glioma D005910 112 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Insulin Resistance D007333 99 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

Download all related citations
Per page 10 20 50 100 | Total 950
Authors Title Published Journal PubMed Link
Mann FM et al. Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis. 2011 FEBS Lett. pmid:21237161
Busch S and Unruh T The influence of additives on the nanoscopic dynamics of the phospholipid dimyristoylphosphatidylcholine. 2011 Biochim. Biophys. Acta pmid:21036141
Shareck J and Belhumeur P Modulation of morphogenesis in Candida albicans by various small molecules. 2011 Eukaryotic Cell pmid:21642508
Yang L et al. ZL11n is a novel nitric oxide-releasing derivative of farnesylthiosalicylic acid that induces apoptosis in human hepatoma HepG2 cells via MAPK/mitochondrial pathways. 2011 Biochem. Biophys. Res. Commun. pmid:21621522
Barkan B et al. Phenotypic reversion of invasive neurofibromin-deficient schwannoma by FTS: Ras inhibition reduces BMP4/Erk/Smad signaling. 2011 Mol. Cancer Ther. pmid:21632464
Yoo S et al. Antimicrobial traits of tea- and cranberry-derived polyphenols against Streptococcus mutans. 2011 Caries Res. pmid:21720161
Fitzpatrick AH et al. Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis. 2011 Plant J. pmid:21395888
Nevo Y et al. The Ras antagonist, farnesylthiosalicylic acid (FTS), decreases fibrosis and improves muscle strength in dy/dy mouse model of muscular dystrophy. 2011 PLoS ONE pmid:21445359
Khan R and Sultana S Farnesol attenuates 1,2-dimethylhydrazine induced oxidative stress, inflammation and apoptotic responses in the colon of Wistar rats. 2011 Chem. Biol. Interact. pmid:21453689
Gonçalves O et al. Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains. 2011 Mutat. Res. pmid:21453784
Zhang L et al. Bisbibenzyls, a new type of antifungal agent, inhibit morphogenesis switch and biofilm formation through upregulation of DPP3 in Candida albicans. 2011 PLoS ONE pmid:22174935
Hall RA et al. The quorum-sensing molecules farnesol/homoserine lactone and dodecanol operate via distinct modes of action in Candida albicans. 2011 Eukaryotic Cell pmid:21666074
Fong C et al. Monodisperse nonionic isoprenoid-type hexahydrofarnesyl ethylene oxide surfactants: high throughput lyotropic liquid crystalline phase determination. 2011 Langmuir pmid:21294552
Kraitzer A et al. Composite fiber structures with antiproliferative agents exhibit advantageous drug delivery and cell growth inhibition in vitro. 2011 J Pharm Sci pmid:20623695
Sharma M and Prasad R The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans. 2011 Antimicrob. Agents Chemother. pmid:21768514
Nishimori R et al. Biosynthesis of unnatural bacteriochlorophyll c derivatives esterified with α,ω-diols in the green sulfur photosynthetic bacterium Chlorobaculum tepidum. 2011 Biochemistry pmid:21846125
Riely GJ et al. A phase II trial of Salirasib in patients with lung adenocarcinomas with KRAS mutations. 2011 J Thorac Oncol pmid:21847063
Ganguly S et al. Zap1 control of cell-cell signaling in Candida albicans biofilms. 2011 Eukaryotic Cell pmid:21890817
Dinamarco TM et al. Farnesol-induced cell death in the filamentous fungus Aspergillus nidulans. 2011 Biochem. Soc. Trans. pmid:21936849
Mor A et al. Inhibition of contact sensitivity by farnesylthiosalicylic acid-amide, a potential Rap1 inhibitor. 2011 J. Invest. Dermatol. pmid:21716322