2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Candidiasis, Invasive D058365 2 associated lipids
Lung Injury D055370 14 associated lipids
Nerve Sheath Neoplasms D018317 4 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Anisakiasis D017129 2 associated lipids
Head Injuries, Closed D016489 5 associated lipids
HIV Infections D015658 20 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Osteosarcoma D012516 50 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Precancerous Conditions D011230 48 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Neuroblastoma D009447 66 associated lipids
Neuritis, Autoimmune, Experimental D009444 4 associated lipids
Neurilemmoma D009442 10 associated lipids
Neuralgia D009437 28 associated lipids
Nephritis D009393 19 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Neoplasms, Glandular and Epithelial D009375 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

Download all related citations
Per page 10 20 50 100 | Total 950
Authors Title Published Journal PubMed Link
Deveau A and Hogan DA Linking quorum sensing regulation and biofilm formation by Candida albicans. 2011 Methods Mol. Biol. pmid:21031315
de Castro Pimentel Figueiredo B et al. The Aspergillus nidulans nucA(EndoG) homologue is not involved in cell death. 2011 Eukaryotic Cell pmid:21131437
Gomes F et al. Farnesol as antibiotics adjuvant in Staphylococcus epidermidis control in vitro. 2011 Am. J. Med. Sci. pmid:21107231
Shareck J and Belhumeur P Modulation of morphogenesis in Candida albicans by various small molecules. 2011 Eukaryotic Cell pmid:21642508
Yoo S et al. Antimicrobial traits of tea- and cranberry-derived polyphenols against Streptococcus mutans. 2011 Caries Res. pmid:21720161
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Borbath I and Stärkel P Chemoprevention of hepatocellular carcinoma. Proof of concept in animal models. 2011 Acta Gastroenterol. Belg. pmid:21563652
Zhang L et al. Bisbibenzyls, a new type of antifungal agent, inhibit morphogenesis switch and biofilm formation through upregulation of DPP3 in Candida albicans. 2011 PLoS ONE pmid:22174935
Biran A et al. Downregulation of survivin and aurora A by histone deacetylase and RAS inhibitors: a new drug combination for cancer therapy. 2011 Int. J. Cancer pmid:20473860
Madhani HD Quorum sensing in fungi: Q&A. 2011 PLoS Pathog. pmid:22046125
Gomes F et al. Effect of farnesol on structure and composition of Staphylococcus epidermidis biofilm matrix. 2011 Curr. Microbiol. pmid:21800262
Pammi M et al. Farnesol decreases biofilms of Staphylococcus epidermidis and exhibits synergy with nafcillin and vancomycin. 2011 Pediatr. Res. pmid:21857375
Teodoro JS et al. Hepatic FXR: key regulator of whole-body energy metabolism. 2011 Trends Endocrinol. Metab. pmid:21862343
Goto T et al. Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21862726
Fitzpatrick AH et al. Roles for farnesol and ABA in Arabidopsis flower development. 2011 Plant Signal Behav pmid:21758018
Mor A et al. Ras inhibition induces insulin sensitivity and glucose uptake. 2011 PLoS ONE pmid:21738773
Sharma M and Prasad R The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans. 2011 Antimicrob. Agents Chemother. pmid:21768514
Nishimori R et al. Biosynthesis of unnatural bacteriochlorophyll c derivatives esterified with α,ω-diols in the green sulfur photosynthetic bacterium Chlorobaculum tepidum. 2011 Biochemistry pmid:21846125
Tsuji F et al. The geranyl-modified tryptophan residue is crucial for ComXRO-E-2 pheromone biological activity. 2011 Bioorg. Med. Chem. Lett. pmid:21636272