2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Precancerous Conditions D011230 48 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

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Authors Title Published Journal PubMed Link
pmid:
Egozi Y et al. Growth inhibition of ras-dependent tumors in nude mice by a potent ras-dislodging antagonist. 1999 Int. J. Cancer pmid:10074926
Machida K et al. Farnesol-induced growth inhibition in Saccharomyces cerevisiae by a cell cycle mechanism. 1999 Microbiology (Reading, Engl.) pmid:10075411
Parmryd I and Dallner G In vivo prenylation of rat proteins: modification of proteins with penta- and hexaprenyl groups. 1999 Arch. Biochem. Biophys. pmid:10190969
Luft UC et al. Farnesol blocks the L-type Ca2+ channel by targeting the alpha 1C subunit. 1999 Arterioscler. Thromb. Vasc. Biol. pmid:10195923
Hanson JR and Nyfeler R Studies in terpenoid biosynthesis. Part 18. Biosynthesis of culmorin. 1976 J. Chem. Soc. Perkin Trans. I pmid:1034641
Weisz B et al. A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice. 1999 Oncogene pmid:10353601
Benford HL et al. Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs. 1999 Mol. Pharmacol. pmid:10385693
Anthony ML et al. Inhibition of phosphatidylcholine biosynthesis following induction of apoptosis in HL-60 cells. 1999 J. Biol. Chem. pmid:10391908
Andres DA et al. Rapid identification of cysteine-linked isoprenyl groups by metabolic labeling with [3H]farnesol and [3H]geranylgeraniol. 1999 Methods Mol. Biol. pmid:10399149