| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
2E,6E-farnesol
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
Cross Reference
Introduction
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2E,6E-farnesol?
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
PubChem Associated disorders and diseases
What pathways are associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2E,6E-farnesol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2E,6E-farnesol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2E,6E-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Geraldo IM et al. | Rapid antibacterial activity of 2 novel hand soaps: evaluation of the risk of development of bacterial resistance to the antibacterial agents. | 2008 | Infect Control Hosp Epidemiol | pmid:18616390 |
| Shintre MS et al. | Evaluation of an alcohol-based surgical hand disinfectant containing a synergistic combination of farnesol and benzethonium chloride for immediate and persistent activity against resident hand flora of volunteers and with a novel in vitro pig skin model. | 2007 | Infect Control Hosp Epidemiol | pmid:17265401 |
| Goodman CL et al. | Partial morphological and functional characterization of the corpus allatum-corpus cardiacum complex from the two-spotted stinkbug, Perillus bioculatus (Hemiptera: Pentatomidae). | 2005 Mar-Apr | In Vitro Cell. Dev. Biol. Anim. | pmid:16029075 |
| Gallagher BM and Hartig WJ | Hormonal studies of uridine utilization in an insect cell line CP-1268 derived from the codling moth Laspeyresia pomonella. | 1976 | In Vitro | pmid:184032 |
| Hirohata S et al. | Inhibition of human B cell activation by a novel nonsteroidal anti-inflammatory drug, indometacin famesil. | 1999 | Immunopharmacology | pmid:10598881 |
| Lee SJ and Moon HI | Immunotoxicity activity of the major essential oil of Filipendula glaberrima against Aedes aegypti L. | 2010 | Immunopharmacol Immunotoxicol | pmid:20175741 |
| Katzav A et al. | Inhibition of ras by farnesylthiosalicylate significantly reduces the levels of autoantibodies in two animal models of the antiphospholipid syndrome. | 2003 | Immunobiology | pmid:12638903 |
| Aronovich R et al. | Antiphospholipid antibodies, thrombin and LPS activate brain endothelial cells and Ras-dependent pathways through distinct mechanisms. | 2005 | Immunobiology | pmid:16325498 |
| Jahangir T et al. | Farnesol prevents Fe-NTA-mediated renal oxidative stress and early tumour promotion markers in rats. | 2006 | Hum Exp Toxicol | pmid:16758765 |
| Nery AL and Nascif R | [Analysis of the value of the product geranyl farnesyl acetate (Gefarnate) in the treatment of peptic ulcer]. | 1966 | Hospital (Rio J) | pmid:5295886 |
| Vilela MP and Mincis M | [Use of geranyl farnesylacetate in patients with non-specific ulcerative rectocolitis]. | 1967 | Hospital (Rio J) | pmid:5304032 |
| Mizukami Y | [Oleylamine (long-chain fatty amine)-induced cell death through MAP kinase pathways in human pancreatic cancer cells]. | 2002 | Hokkaido Igaku Zasshi | pmid:11868368 |
| Mallat A et al. | Effect of simvastatin, an inhibitor of hydroxy-methylglutaryl coenzyme A reductase, on the growth of human Ito cells. | 1994 | Hepatology | pmid:7982659 |
| Peter MG et al. | [On the incorporation of geraniol and farnesol into cantharidin (author's transl)]. | 1977 | Helv. Chim. Acta | pmid:558966 |
| Peter MG et al. | [Identification of farnesol as an intermediate in the biosynthesis of cantharidin from mevalonolactone]. | 1977 | Helv. Chim. Acta | pmid:599044 |
| Peter MG et al. | [Incorporation experiments with (3H and 14C) doubly labelled farnesols into cantharidin (author's transl)]. | 1977 | Helv. Chim. Acta | pmid:893117 |
| Smith PM et al. | Proceedings: A double blind trial of carbenoxolone and geranyl farnesylacetate in gastric ulcer. | 1974 | Gut | pmid:4611753 |
| Jensen EC et al. | Farnesol restores wild-type colony morphology to 96% of Candida albicans colony morphology variants recovered following treatment with mutagens. | 2006 | Genome | pmid:16699554 |
| Bryant PJ and Sang JH | Physiological genetics of melanotic tumors in Drosophila melanogaster. VI. The tumorigenic effects of juvenile hormone-like substances. | 1969 | Genetics | pmid:5371022 |
| Lombardi L et al. | Circadian rhythms in Neurospora crassa: clock mutant effects in the absence of a frq-based oscillator. | 2007 | Genetics | pmid:17237512 |
| Semighini CP et al. | Functional characterization of the putative Aspergillus nidulans poly(ADP-ribose) polymerase homolog PrpA. | 2006 | Genetics | pmid:16510786 |
| Tamone SL et al. | Identification and characterization of methyl farnesoate binding proteins from the crab, Cancer magister. | 1997 | Gen. Comp. Endocrinol. | pmid:9038249 |
| Andries JC | [Experimental induction of morphogenesis and degeneration of mesentery in Aeshna cyana (Insecta, Odonata)]. | 1979 | Gen. Comp. Endocrinol. | pmid:499746 |
| Bendena WG et al. | Evidence for differential biosynthesis of juvenile hormone (and related) sesquiterpenoids in Drosophila melanogaster. | 2011 | Gen. Comp. Endocrinol. | pmid:21354154 |
| McCaffery AR and Highnam KC | Effects of corpus aliatum hormone and its mimics on the activity of the cerebral neurosecretory system of Locusta migratoria migratorioides R. & F. | 1975 | Gen. Comp. Endocrinol. | pmid:1132652 |
| De Loof A | The essence of female-male physiological dimorphism: differential Ca2+-homeostasis enabled by the interplay between farnesol-like endogenous sesquiterpenoids and sex-steroids? The Calcigender paradigm. | 2015 | Gen. Comp. Endocrinol. | pmid:25540913 |
| Laverdure AM | [Hormonal conditions necessary for evolution of the ovary in the pupa of Tenebrio molitor (Coleoptera)]. | 1971 | Gen. Comp. Endocrinol. | pmid:5166855 |
| Prestwich GD et al. | Binding proteins for methyl farnesoate in lobster tissues: detection by photoaffinity labeling. | 1990 | Gen. Comp. Endocrinol. | pmid:2074002 |
| Bustinza-Linares E et al. | Salirasib in the treatment of pancreatic cancer. | 2010 | Future Oncol | pmid:20528225 |
| Langford ML et al. | Cellular interactions of farnesol, a quorum-sensing molecule produced by Candida albicans. | 2009 | Future Microbiol | pmid:19995193 |
| Dinamarco TM et al. | The roles played by Aspergillus nidulans apoptosis-inducing factor (AIF)-like mitochondrial oxidoreductase (AifA) and NADH-ubiquinone oxidoreductases (NdeA-B and NdiA) in farnesol resistance. | 2010 | Fungal Genet. Biol. | pmid:20654725 |
| de Oliveira Júnior WM et al. | Farnesol: antinociceptive effect and histopathological analysis of the striatum and hippocampus of mice. | 2013 | Fundam Clin Pharmacol | pmid:22340189 |
| Tampalini L and Vaglia A | [Farnesyl acetate in the treatment of dyspepsia]. | 1968 Jul-Aug | Fracastoro | pmid:5707402 |
| Zini L | [Ambulatory treatment of mild forms of "malabsorption syndrome" with Gefarnil]. | 1968 Jul-Aug | Fracastoro | pmid:5707403 |
| Lapczynski A et al. | Fragrance material review on farnesol. | 2008 | Food Chem. Toxicol. | pmid:18640198 |
| Jaggi AS and Singh N | Analgesic potential of intrathecal farnesyl thiosalicylic acid and GW 5074 in vincristine-induced neuropathic pain in rats. | 2012 | Food Chem. Toxicol. | pmid:22326968 |
| Doan K et al. | In vivo and in vitro skin absorption of lipophilic compounds, dibutyl phthalate, farnesol and geraniol in the hairless guinea pig. | 2010 | Food Chem. Toxicol. | pmid:19747520 |
| Ha J et al. | Determination of E,E-farnesol in Makgeolli (rice wine) using dynamic headspace sampling and stir bar sorptive extraction coupled with gas chromatography-mass spectrometry. | 2014 | Food Chem | pmid:24001815 |
| Han TL et al. | The metabolic response of Candida albicans to farnesol under hyphae-inducing conditions. | 2012 | FEMS Yeast Res. | pmid:22846172 |
| Gori K et al. | Alcohol-based quorum sensing plays a role in adhesion and sliding motility of the yeast Debaryomyces hansenii. | 2011 | FEMS Yeast Res. | pmid:22093748 |
| Jabra-Rizk MA et al. | Effect of farnesol on Candida dubliniensis biofilm formation and fluconazole resistance. | 2006 | FEMS Yeast Res. | pmid:17042756 |
| Inoue Y et al. | The antibacterial effects of terpene alcohols on Staphylococcus aureus and their mode of action. | 2004 | FEMS Microbiol. Lett. | pmid:15321680 |
| Kuroda M et al. | Sesquiterpene farnesol as a competitive inhibitor of lipase activity of Staphylococcus aureus. | 2007 | FEMS Microbiol. Lett. | pmid:17559400 |
| Semighini CP et al. | Inhibition of Fusarium graminearum growth and development by farnesol. | 2008 | FEMS Microbiol. Lett. | pmid:18201191 |
| Ghosh S et al. | Candida albicans cell wall components and farnesol stimulate the expression of both inflammatory and regulatory cytokines in the murine RAW264.7 macrophage cell line. | 2010 | FEMS Immunol. Med. Microbiol. | pmid:20618847 |
| Van der Kloot WG | Goals and strategy of comparative pharmacology. | 1967 Jul-Aug | Fed. Proc. | pmid:6028781 |
| Tachibana A et al. | Evidence for farnesol-mediated isoprenoid synthesis regulation in a halophilic archaeon, Haloferax volcanii. | 1996 | FEBS Lett. | pmid:8566226 |
| Mann FM et al. | Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis. | 2011 | FEBS Lett. | pmid:21237161 |
| Machida K and Tanaka T | Farnesol-induced generation of reactive oxygen species dependent on mitochondrial transmembrane potential hyperpolarization mediated by F(0)F(1)-ATPase in yeast. | 1999 | FEBS Lett. | pmid:10580101 |
| Beedle AS et al. | The stereochemistry of the reduction of mevaldic acid-coenzyme A hemithioacetal by rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1972 | FEBS Lett. | pmid:4405222 |