| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
2E,6E-farnesol
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
Cross Reference
Introduction
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2E,6E-farnesol?
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
PubChem Associated disorders and diseases
What pathways are associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2E,6E-farnesol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2E,6E-farnesol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2E,6E-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gefarnate. | 1968 | Drug Ther Bull | pmid:5722353 | |
| Mincis M | [Clinical study of the effect of geranyl of farnesylacetate combined with nafiver in peptic ulcer patients]. | 1968 | Rev Bras Med | pmid:5724217 |
| Tampalini L and Vaglia A | [Farnesyl acetate in the treatment of dyspepsia]. | 1968 Jul-Aug | Fracastoro | pmid:5707402 |
| Zini L | [Ambulatory treatment of mild forms of "malabsorption syndrome" with Gefarnil]. | 1968 Jul-Aug | Fracastoro | pmid:5707403 |
| Sofer SS and Rilling HC | Mechanism of squalene biosynthesis: evidence against the involvement of free nerolidyl pyrophosphate. | 1969 | J. Lipid Res. | pmid:4305712 |
| Popják G et al. | Artificial substrates for prenyltransferase. | 1969 | Biochem. J. | pmid:4309597 |
| Christenson JG et al. | Enzymatic synthesis of the antigen carrier lipid. | 1969 | J. Biol. Chem. | pmid:4311788 |
| Etemadi AH et al. | Assay of the possible organization of particle-bound enzymes with squalene synthetase and squalene oxidocyclase systems. | 1969 | Biochem. J. | pmid:4388240 |
| Popják G et al. | Biosynthesis and structure of a new intermediate between farnesyl pyrophosphate and squalene. | 1969 | J. Biol. Chem. | pmid:4388617 |
| Popják G et al. | Synthesis of 10,11-dihydrofarnesyl pyrophosphate from 6,7-dihydrogeranyl pyrophosphate by prenyltransferase. | 1969 | Biochem. J. | pmid:4304159 |
| Coppi G et al. | [Cicatricial action of trifarnesylacetate of pantothenile (DA 1813) on normal wounds and on whounds aggravated by corticoid treatment in rats]. | 1969 | Boll. Soc. Ital. Biol. Sper. | pmid:5346779 |
| Coppi G et al. | [The antifungal properties of homofarnesoyl-hydroxamic acid (DA 2209)]. | 1969 | Boll Chim Farm | pmid:5354276 |
| Bryant PJ and Sang JH | Physiological genetics of melanotic tumors in Drosophila melanogaster. VI. The tumorigenic effects of juvenile hormone-like substances. | 1969 | Genetics | pmid:5371022 |
| Emmerich H and Thiele HU | [Effect of farnesyl methyl ether on maturation of the Pterostichus nigrita F ovary]. | 1969 | Naturwissenschaften | pmid:5375112 |
| Coppi G and Bonardi G | Synthesis of 14C-labelled geranyl farnesylacetate (gefarnate). | 1969 | Arzneimittelforschung | pmid:5394524 |
| JarolÃm V et al. | Natural and synthetic materials with insect hormones activity. 8. Juvenile activity of the farnesane-type compounds on Galleria mellonella. | 1969 | Life Sci. | pmid:5803377 |
| Calam DH | Species and sex-specific compounds from the heads of male bumblebees (Bombus spp.). | 1969 | Nature | pmid:5765060 |
| Novák VJ | Morphogenetic analysis of the effects of juvenile hormone analogues and other morphogenetically active substances on embryos of Schistocerca gregaria (Forskål). | 1969 | J Embryol Exp Morphol | pmid:5765790 |
| Delage B | [Sterols and terpenes of insects]. | 1969 Jul-Aug | Annee Biol | pmid:4900064 |
| Heinstein PF et al. | Biosynthesis of gossypol. Incorporation of mevalonate-2-14C and isoprenyl pyrophosphates. | 1970 | J. Biol. Chem. | pmid:4318479 |
| Gough DP and Hemming FW | The characterization and stereochemistry of biosynthesis of dolichols in rat liver. | 1970 | Biochem. J. | pmid:4319540 |
| Flint AP | The activity and kinetic properties of mevalonate kinase in superovulated rat ovary. | 1970 | Biochem. J. | pmid:4321929 |
| Dialameh GH et al. | Enzymatic alkylation of menaquinone-o to menaquinones microsomes from chick liver. | 1970 | Biochim. Biophys. Acta | pmid:4323518 |
| Epstein WW and Rilling HC | Studies on the mechanism of squalene biosynthesis. The structure of presqualene pyrophosphate. | 1970 | J. Biol. Chem. | pmid:4318477 |
| Popják G | Lessons learnt from small molecules. | 1970 | Biochem. Soc. Symp. | pmid:4925074 |
| Hecht SM | Mass spectrometric identification of some prenylaminopurines. | 1970 | Biochim. Biophys. Acta | pmid:5507911 |
| van Tamelen EE and McCormick JP | Synthesis of cecropia juvenile hormone from trans,trans-farnesol. | 1970 | J. Am. Chem. Soc. | pmid:5411064 |
| Shanta CS and Meerovitch E | Specific inhibition of morphogenesis in Trichinella spiralis by insect juvenile hormone mimics. | 1970 | Can. J. Zool. | pmid:5475084 |
| NÄ•mec V et al. | Natural and synthetic materials with insect hormone activity. 7. Juvenile activity of the farnesane-type compounds on Locusta migratoria L and Schistocerca gregaria (Forsk). | 1970 | Life Sci. II | pmid:5478093 |
| Jautelat M et al. | Natural-abundance 13C nuclear magnetic resonance spectra of terpenes and carotenes. | 1970 | Proc. Natl. Acad. Sci. U.S.A. | pmid:5263764 |
| Laverdure AM | [Effect of ecdysone and methyl ester of farnesol on the nymphal ovary of Tenebrio molitor (Coleoptera) cultivated in vitro]. | 1970 May-Jun | Ann. Endocrinol. (Paris) | pmid:5455244 |
| George-Nascimento C et al. | Non enzymic formation of nerolidol from farnesyl pyrophosphate in the presence of bivalent cations. | 1971 | Biochem. Biophys. Res. Commun. | pmid:4334520 |
| Kurokawa T et al. | Formation of polyprenyl phosphates by a cell-free enzyme of Micrococcus lysodeikticus. | 1971 | Biochem. Biophys. Res. Commun. | pmid:4334524 |
| Edmond J et al. | Presqualene alcohol. Further evidence on the structure of a C 30 precursor of squalene. | 1971 | J. Biol. Chem. | pmid:4399596 |
| Castelli A et al. | Effect of hydroxy analogs of coenzyme Q on DPNH- and succin-oxidase activities of yeast mitochondria. | 1971 | Biochem. Biophys. Res. Commun. | pmid:4324835 |
| Hamilton JA and Cox GB | Ubiquinone biosynthesis in Escherichia coli K-12. Accumulation of an octaprenol, farnesylfarnesylgeraniol, by a multiple aromatic auxotroph. | 1971 | Biochem. J. | pmid:4942305 |
| Abu-Mustafa EA et al. | Natural coumarins. XII. Umbelliprenin, a constituent of ammi majus L. fruits. | 1971 | J Pharm Sci | pmid:5125784 |
| Hintze-Podufal C | The juvenile hormone-like effect of farnesol derivatives on the pupal development of Cerura vinula L. | 1971 | Z. Naturforsch. B | pmid:4396584 |
| Metzler M et al. | On the biosynthesis of juvenile hormone in the adult Cecropia moth. | 1971 | Z. Naturforsch. B | pmid:4401880 |
| Alam SS et al. | Prenol phosphates and mannosyltransferases. | 1971 | Biochem. J. | pmid:5116535 |
| Davey KG | Molting in a parasitic nematode, Phocanema decipiens. VI. The mode of action of insect juvenile hormone and farnesyl methyl ether. | 1971 | Int. J. Parasitol. | pmid:5161204 |
| Laverdure AM | [Hormonal conditions necessary for evolution of the ovary in the pupa of Tenebrio molitor (Coleoptera)]. | 1971 | Gen. Comp. Endocrinol. | pmid:5166855 |
| Gadolini A and Facchielli G | [Gas-chromatographic behavior of gefarnate]. | 1971 | Boll Chim Farm | pmid:5147982 |
| Brockmann H and Knobloch G | [A new bacteriochlorophyll from Rhodospirillum rubrum]. | 1972 | Arch Mikrobiol | pmid:4627398 |
| Richards JB and Hemming FW | Dolichols, ubiquinones, geranylgeraniol and farnesol as the major metabolites of mevalonate in Phytophthora cactorum. | 1972 | Biochem. J. | pmid:4643705 |
| Levinson HZ | [The evolution and biosynthesis of the terpinoid pheromones and hormones]. | 1972 | Naturwissenschaften | pmid:4571813 |
| Rilling HC | The effect of sterol carrier protein on squalene synthesis. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4400440 |
| Dugan RE and Porter JW | Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction. | 1972 | Arch. Biochem. Biophys. | pmid:4403691 |
| Walton MJ and Pennock JF | Some studies on the biosynthesis of ubiguinone, isoprenoid alcohols, squalene and sterols by marine invertebrates. | 1972 | Biochem. J. | pmid:4403925 |
| Qureshi AA et al. | Lycopersene and prelycopersene pyrophosphate. Intermediates in carotene biosynthesis. | 1972 | J. Biol. Chem. | pmid:4403969 |
| Warren CD and Jeanloz RW | Chemical synthesis of pyrophosphodiesters of carbohydrates and isoprenoid alcohols. Lipid intermediates of bacterial cell wall and antigenic polysaccharide biosynthesis. | 1972 | Biochemistry | pmid:4339875 |
| Slakey LL et al. | The effects of fasting, refeeding, and time of day on the levels of enzymes effecting the conversion of -hydroxy- -methylglutaryl-coenzyme A to squalene. | 1972 | J. Biol. Chem. | pmid:4337504 |
| Polito A et al. | Artificial substrates in squalene and sterol biosynthesis. | 1972 | J. Biol. Chem. | pmid:4337856 |
| Stone KJ and Strominger JL | Inhibition of sterol biosynthesis by bacitracin. | 1972 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4338587 |
| Qureshi AA et al. | Squalene synthetase. I. Dissociation and reassociation of enzyme complex. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4341049 |
| Heintz R et al. | Plant sterol metabolism. Demonstration and identification of a biosynthetic intermediate between farnesyl PP and squalene in a higher plant. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4344813 |
| Canonica L et al. | Biosynthesis of mycophenolic acid. | 1972 | J. Chem. Soc. Perkin Trans. I | pmid:4674609 |
| Beedle AS et al. | The stereochemistry of hydrogen transfer from NADPH catalysed by 3-hydroxy-3-methylglutaryl-coenzyme A reductase from rat liver. | 1972 | Eur. J. Biochem. | pmid:4403574 |
| Beedle AS et al. | The stereochemistry of the reduction of mevaldic acid-coenzyme A hemithioacetal by rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1972 | FEBS Lett. | pmid:4405222 |
| Akisue G | [Secretion of Myroxylon peruiforum L.f. 3. Physical and chemical characterization of essential oil from balsam and qualitative analysis of various componets]. | 1972 Jul-Dec | Rev Farm Bioquim Univ Sao Paulo | pmid:4664898 |
| Binet L et al. | [Farnesol, psychosedative and spasmolytic drug]. | 1972 Sep-Oct | Therapie | pmid:4405589 |
| Madhavan K et al. | Farnesol metabolism in Drosophila melanogaster: ontogeny and tissue distribution of octanol dehydrogenase and aldehyde oxidase. | 1973 | J. Insect Physiol. | pmid:4631837 |
| Langman MJ et al. | Treatment of chronic gastric ulcer with carbenoxolone and gefarnate: a comparative trial. | 1973 | Br Med J | pmid:4577839 |
| Newman CR and Montgomery DA | A double-blind trial of oral gefarnate in duodenal ulcer. | 1973 | Br J Clin Pract | pmid:4580209 |
| Ichiki H and Isoda M | The Mann-Williamson ulcer as a model for testing antiulcer drugs. Results obtained with gefarnate. | 1973 | Arzneimittelforschung | pmid:4740136 |
| Qureshi AA et al. | Squalene synthetase. II. Purification and properties of bakers' yeast enzyme. | 1973 | J. Biol. Chem. | pmid:4348552 |
| Beytia E et al. | Squalene synthetase. 3. Mechanism of the reaction. | 1973 | J. Biol. Chem. | pmid:4348553 |
| Slakey LL et al. | Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta. | 1973 | J. Lipid Res. | pmid:4351784 |
| Derksen A and Cohen P | Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro. | 1973 | J. Biol. Chem. | pmid:4355579 |
| Shechter I | Biosynthesis of trans-farnesyl triphosphate in Gibberella fujikuroi. | 1973 | Biochim. Biophys. Acta | pmid:4795388 |
| Qureshi AA et al. | Biosynthesis of prelycopersene pyrophosphate and lycopersene by squalene synthetase. | 1973 | J. Biol. Chem. | pmid:4144543 |
| Smith PM et al. | Proceedings: A double blind trial of carbenoxolone and geranyl farnesylacetate in gastric ulcer. | 1974 | Gut | pmid:4611753 |
| Keenan MV and Allen CM | Characterization of undecaprenyl pyrophosphate synthetase from Lactobacillus plantarum. | 1974 | Arch. Biochem. Biophys. | pmid:4599964 |
| Sharma RN and Saxena KN | Orientation and developmental inhibition in the housefly by certain terpenoids. | 1974 | J. Med. Entomol. | pmid:4281838 |
| Beedle AS et al. | Studies on the biosynthesis of tetrahymanol in Tetrahymena pyriformis. The mechanism of inhibition by cholesterol. | 1974 | Biochem. J. | pmid:4140721 |
| Davey KG and Sommerville RI | Molting in a parasitic nematode, Phocanema decipiens. VII. The mode of action of the ecdysial hormone. | 1974 | Int. J. Parasitol. | pmid:4853251 |
| Tanaka S et al. | Stereoselective epoxidations of acyclic allylic alcohols by transition metal--hydroperoxide reagents. Synthesis of dl-C18 Cecropia juvenile hormone from farnesol. | 1974 | J. Am. Chem. Soc. | pmid:4854400 |
| Cardemil E et al. | Separation of isoprenoid alcohols and aldehydes by thin-layer chromatography. | 1974 | Anal. Biochem. | pmid:4838788 |
| Styczyńska B et al. | [Assessment of the activity of insect hormone analogues. I. Derivatives of 2,3-methylenefarnesol and 2,3-methylenefarnesenic acid]. | 1974 | Rocz Panstw Zakl Hig | pmid:4842239 |
| Tofts J and Meerovitch E | The effect of farnesyl methyl ether, a mimic of insect juvenile hormone, on Hymenolepis Diminuta in vitro. | 1974 | Int. J. Parasitol. | pmid:4822487 |
| Pratt GE and Tobe SS | Juvenile hormones radiobiosynthesised by corpora allata of adult female locusts in vitro. | 1974 | Life Sci. | pmid:4823991 |
| Muscio F et al. | Prequalene pyrophosphate. A normal intermediate in squalene biosynthesis. | 1974 | J. Biol. Chem. | pmid:4152099 |
| Tobe SS and Pratt GE | The influence of substrate concentrations on the rate of insect juvenile hormone biosynthesis by corpora allata of the desert locust in vitro. | 1974 | Biochem. J. | pmid:4462567 |
| Lanzrein B | Influence of a juvenile hormone analogue on vitellogenin synthesis and oögenesis in larvae of Nauphoeta cinerea. | 1974 | J. Insect Physiol. | pmid:4413859 |
| Imai K et al. | Letter: Derivation of (plus)- and (minus)-C17-juvenile hormone from its racemic alcohol derivative via fungal metabolism. | 1974 | J. Am. Chem. Soc. | pmid:4414179 |
| Shechter I | Phosphate transfer from trans-farnesyl triphosphate to AMP in Gibberella fujikuroi. | 1974 | Biochim. Biophys. Acta | pmid:4423368 |
| Overton KH and Roberts FM | Biosynthesis of trans, trans- and cis, trans-farnesols by soluble enzymes from tissue cultures of Andrographis paniculata. | 1974 | Biochem. J. | pmid:4468823 |
| Ellsworth RK and Nowak CA | A gas chromatographic-mass spectrometric analysis of the esterifying alcohols of pumpkin seed protochlorophylls. | 1974 | Anal. Biochem. | pmid:4362215 |
| Samuel O et al. | Preparation of (1-3H) polyprenyl pyrophosphates. | 1974 | Biochimie | pmid:4375498 |
| Morozova NP et al. | [The effect of a controlled gas atmosphere on farnesene dynamics and the development of sunburn in apples]. | 1974 Jul-Aug | Prikl. Biokhim. Mikrobiol. | pmid:4453546 |
| Green TR et al. | Compartmentation of isopentenyl pyophosphate isomerase and prenyl transferase in developing castor bean endosperm. | 1975 | Biochem. Biophys. Res. Commun. | pmid:167761 |
| Menn JJ and Pallow FM | Development of morphogenetic agents in insect control. | 1975 | Environ Lett | pmid:1091483 |
| McCaffery AR and Highnam KC | Effects of corpus aliatum hormone and its mimics on the activity of the cerebral neurosecretory system of Locusta migratoria migratorioides R. & F. | 1975 | Gen. Comp. Endocrinol. | pmid:1132652 |
| Binet P et al. | [Farnesol and neuroleptics. I. Reinforcement by farnesol of the experimental cataleptigenic effect of neuroleptics]. | 1975 | Ann Pharm Fr | pmid:1239975 |
| Fogelman AM et al. | Abnormal induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase in leukocytes from subjects with heterozygous familial hypercholesterolemia. | 1975 | J. Biol. Chem. | pmid:1116997 |
| Binet P et al. | [Farnesol and neuroleptics. II. Action of farnesol, alone or associated with a neuroleptic, on the stereotypies induced in the rat by amphetamine]. | 1975 Jun-Jul | Ann Pharm Fr | pmid:1241259 |
| L'Helias C | [Juvenile hormone in diapausing Pieris brassicae and mutations. Tetrahydrofolic acid and pterins incubated in chrysalids, provoking ontogenic and mutagenic genetic information alterations in Drosophila melanogaster]. | 1975 Mar-Apr | Ann. Endocrinol. (Paris) | pmid:172004 |
| Ledoux A | [Effect of a farnesol derivative on the appearance of winged females in aphaenogaster senilis (Hymenoptera, Formicoidea)]. | 1976 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:817818 |
| Gallagher BM and Hartig WJ | Hormonal studies of uridine utilization in an insect cell line CP-1268 derived from the codling moth Laspeyresia pomonella. | 1976 | In Vitro | pmid:184032 |
| Verzár-Petri G et al. | [Determination of the composition of camomile oil]. | 1976 | Pharmazie | pmid:935231 |