| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
2E,6E-farnesol
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
Cross Reference
Introduction
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2E,6E-farnesol?
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
PubChem Associated disorders and diseases
What pathways are associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2E,6E-farnesol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2E,6E-farnesol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2E,6E-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen M et al. | Use of synthetic isoprenoids to target protein prenylation and Rho GTPases in breast cancer invasion. | 2014 | PLoS ONE | pmid:24587105 |
| Ha J et al. | Determination of E,E-farnesol in Makgeolli (rice wine) using dynamic headspace sampling and stir bar sorptive extraction coupled with gas chromatography-mass spectrometry. | 2014 | Food Chem | pmid:24001815 |
| Bhattacharyya S et al. | Sol-gel silica controlled release thin films for the inhibition of methicillin-resistant Staphylococcus aureus. | 2014 | Biomaterials | pmid:24099711 |
| Matsuzawa T et al. | EFdA, a reverse transcriptase inhibitor, potently blocks HIV-1 ex vivo infection of Langerhans cells within epithelium. | 2014 | J. Invest. Dermatol. | pmid:24384694 |
| Ronderos DS et al. | Farnesol-detecting olfactory neurons in Drosophila. | 2014 | J. Neurosci. | pmid:24623773 |
| Lu Y et al. | Quorum sensing controls hyphal initiation in Candida albicans through Ubr1-mediated protein degradation. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24449897 |
| Sakane C et al. | Inhibition of lysine-specific demethylase 1 by the acyclic diterpenoid geranylgeranoic acid and its derivatives. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24406160 |
| Sabra A et al. | Host-pathogen interaction and signaling molecule secretion are modified in the dpp3 knockout mutant of Candida lusitaniae. | 2014 | Infect. Immun. | pmid:24191303 |
| Chen Y et al. | Targeted delivery of curcumin to tumors via PEG-derivatized FTS-based micellar system. | 2014 | AAPS J | pmid:24706375 |
| Schmukler E et al. | Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death. | 2014 | Oncotarget | pmid:24368422 |
| Cotoras M et al. | Farnesol induces apoptosis-like phenotype in the phytopathogenic fungus Botrytis cinerea. | 2013 Jan-Feb | Mycologia | pmid:22962358 |
| Alves FR et al. | Biofilm biomass disruption by natural substances with potential for endodontic use. | 2013 Jan-Feb | Braz Oral Res | pmid:23306623 |
| de Oliveira Júnior WM et al. | Farnesol: antinociceptive effect and histopathological analysis of the striatum and hippocampus of mice. | 2013 | Fundam Clin Pharmacol | pmid:22340189 |
| Cordeiro RA et al. | Minimum inhibitory concentrations of amphotericin B, azoles and caspofungin against Candida species are reduced by farnesol. | 2013 | Med. Mycol. | pmid:22712455 |
| Farag MA and Al-Mahdy DA | Comparative study of the chemical composition and biological activities of Magnolia grandiflora and Magnolia virginiana flower essential oils. | 2013 | Nat. Prod. Res. | pmid:22690913 |
| Zhang X et al. | PEG-farnesylthiosalicylate conjugate as a nanomicellar carrier for delivery of paclitaxel. | 2013 | Bioconjug. Chem. | pmid:23425093 |
| Brilhante RS et al. | Effect of farnesol on growth, ergosterol biosynthesis, and cell permeability in Coccidioides posadasii. | 2013 | Antimicrob. Agents Chemother. | pmid:23459491 |
| Mor A et al. | Immunomodulatory properties of farnesoids: the new steroids? | 2013 | Curr. Med. Chem. | pmid:23432580 |
| Langford ML et al. | Candida albicans Czf1 and Efg1 coordinate the response to farnesol during quorum sensing, white-opaque thermal dimorphism, and cell death. | 2013 | Eukaryotic Cell | pmid:23873867 |
| Schmukler E et al. | Ras inhibition enhances autophagy, which partially protects cells from death. | 2013 | Oncotarget | pmid:23847721 |
| Wang C et al. | Engineered heterologous FPP synthases-mediated Z,E-FPP synthesis in E. coli. | 2013 | Metab. Eng. | pmid:23608473 |
| Cho SW et al. | Positive regulation of osteogenesis by bile acid through FXR. | 2013 | J. Bone Miner. Res. | pmid:23609136 |
| Gouveia V et al. | Di- and sesquiterpenoids from Cystoseira genus: structure, intra-molecular transformations and biological activity. | 2013 | Mini Rev Med Chem | pmid:23621654 |
| Rivera-Perez C et al. | Aldehyde dehydrogenase 3 converts farnesal into farnesoic acid in the corpora allata of mosquitoes. | 2013 | Insect Biochem. Mol. Biol. | pmid:23639754 |
| Jones S et al. | β-ionone induces cell cycle arrest and apoptosis in human prostate tumor cells. | 2013 | Nutr Cancer | pmid:23659452 |
| Szűcs G et al. | Cardioprotection by farnesol: role of the mevalonate pathway. | 2013 | Cardiovasc Drugs Ther | pmid:23673412 |
| Charette N et al. | Salirasib sensitizes hepatocarcinoma cells to TRAIL-induced apoptosis through DR5 and survivin-dependent mechanisms. | 2013 | Cell Death Dis | pmid:23348585 |
| Schmukler E et al. | Ras inhibition enhances autophagy, which partially protects cells from death. | 2013 | Oncotarget | pmid:23370967 |
| Kraitzer A et al. | Mechanisms of antiproliferative drug release from bioresorbable porous structures. | 2013 | J Biomed Mater Res A | pmid:23065767 |
| Barkan B et al. | Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis. | 2013 | Oncotarget | pmid:23530091 |
| Faigenbaum R et al. | Growth of poorly differentiated endometrial carcinoma is inhibited by combined action of medroxyprogesterone acetate and the Ras inhibitor Salirasib. | 2013 | Oncotarget | pmid:23530112 |
| Xu H et al. | Glucanase induces filamentation of the fungal pathogen Candida albicans. | 2013 | PLoS ONE | pmid:23737947 |
| Nunes PM et al. | Study of trans-trans farnesol effect on hyphae formation by Yarrowia lipolytica. | 2013 | Bioprocess Biosyst Eng | pmid:23715764 |
| Nyati P et al. | Farnesyl phosphatase, a Corpora allata enzyme involved in juvenile hormone biosynthesis in Aedes aegypti. | 2013 | PLoS ONE | pmid:23940797 |
| Onono F et al. | Efficient use of exogenous isoprenols for protein isoprenylation by MDA-MB-231 cells is regulated independently of the mevalonate pathway. | 2013 | J. Biol. Chem. | pmid:23908355 |
| Schokoroy S et al. | Disrupting the oncogenic synergism between nucleolin and Ras results in cell growth inhibition and cell death. | 2013 | PLoS ONE | pmid:24086490 |
| Kloog Y et al. | Ras chaperones: new targets for cancer and immunotherapy. | 2013 | Enzymes | pmid:25033809 |
| Pfister C et al. | Detection and quantification of farnesol-induced apoptosis in difficult primary cell cultures by TaqMan protein assay. | 2013 | Apoptosis | pmid:23315006 |
| Cerca N et al. | Farnesol induces cell detachment from established S. epidermidis biofilms. | 2013 | J. Antibiot. | pmid:23549353 |
| Kuete V and Efferth T | Molecular determinants of cancer cell sensitivity and resistance towards the sesquiterpene farnesol. | 2013 | Pharmazie | pmid:23923645 |
| Alves FR et al. | Antibiofilm and antibacterial activities of farnesol and xylitol as potential endodontic irrigants. | 2013 | Braz Dent J | pmid:23969910 |
| Lazzerini PE et al. | Rosuvastatin inhibits spontaneous and IL-1β-induced interleukin-6 production from human cultured osteoblastic cells. | 2013 | Joint Bone Spine | pmid:22999910 |
| Makovski V et al. | Farnesylthiosalicylic acid (salirasib) inhibits Rheb in TSC2-null ELT3 cells: a potential treatment for lymphangioleiomyomatosis. | 2012 | Int. J. Cancer | pmid:21500191 |
| Tashiro M et al. | Pravastatin inhibits farnesol production in Candida albicans and improves survival in a mouse model of systemic candidiasis. | 2012 | Med. Mycol. | pmid:21954955 |
| Jaggi AS and Singh N | Analgesic potential of intrathecal farnesyl thiosalicylic acid and GW 5074 in vincristine-induced neuropathic pain in rats. | 2012 | Food Chem. Toxicol. | pmid:22326968 |
| Aizman E et al. | Ras inhibition by FTS attenuates brain tumor growth in mice by direct antitumor activity and enhanced reactivity of cytotoxic lymphocytes. | 2012 | Oncotarget | pmid:22323550 |
| Qamar W et al. | Benzo(a)pyrene-induced pulmonary inflammation, edema, surfactant dysfunction, and injuries in rats: alleviation by farnesol. | 2012 | Exp. Lung Res. | pmid:22168545 |
| Mans RA et al. | Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. | 2012 | Neuroscience | pmid:22192838 |
| Mashiach-Farkash E et al. | Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton. | 2012 | Oncotarget | pmid:22776759 |
| Lichtor PA and Miller SJ | Combinatorial evolution of site- and enantioselective catalysts for polyene epoxidation. | 2012 | Nat Chem | pmid:23174978 |