| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
2E,6E-farnesol
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
Cross Reference
Introduction
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2E,6E-farnesol?
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
PubChem Associated disorders and diseases
What pathways are associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2E,6E-farnesol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 2E,6E-farnesol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2E,6E-farnesol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2E,6E-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fukada Y et al. | Farnesylated gamma-subunit of photoreceptor G protein indispensable for GTP-binding. | 1990 | Nature | pmid:2385292 |
| Lowy DR and Willumsen BM | Protein modification: new clue to Ras lipid glue. | 1989 | Nature | pmid:2677741 |
| Calam DH | Species and sex-specific compounds from the heads of male bumblebees (Bombus spp.). | 1969 | Nature | pmid:5765060 |
| Masner P et al. | Sexually spread insect sterility induced by the analogues of juvenile hormone. | 1968 | Nature | pmid:5690848 |
| Farag MA and Al-Mahdy DA | Comparative study of the chemical composition and biological activities of Magnolia grandiflora and Magnolia virginiana flower essential oils. | 2013 | Nat. Prod. Res. | pmid:22690913 |
| Cortés M et al. | Drimenol: A versatile synthon for compounds with trans-drimane skeleton. | 2011 | Nat Prod Commun | pmid:21560760 |
| Lichtor PA and Miller SJ | Combinatorial evolution of site- and enantioselective catalysts for polyene epoxidation. | 2012 | Nat Chem | pmid:23174978 |
| Cotoras M et al. | Farnesol induces apoptosis-like phenotype in the phytopathogenic fungus Botrytis cinerea. | 2013 Jan-Feb | Mycologia | pmid:22962358 |
| Liu P et al. | Farnesol induces apoptosis and oxidative stress in the fungal pathogen Penicillium expansum. | 2010 Mar-Apr | Mycologia | pmid:20361499 |
| Gonçalves O et al. | Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains. | 2011 | Mutat. Res. | pmid:21453784 |
| Jin J et al. | Farnesol, a potential efflux pump inhibitor in Mycobacterium smegmatis. | 2010 | Molecules | pmid:21042264 |
| Å piÄáková A et al. | Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions. | 2017 | Molecules | pmid:28338641 |
| Togashi N et al. | Effects of two terpene alcohols on the antibacterial activity and the mode of action of farnesol against Staphylococcus aureus. | 2008 | Molecules | pmid:19078849 |
| Rung E et al. | Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa cells. | 2006 | Mol. Reprod. Dev. | pmid:16868926 |
| Benford HL et al. | Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs. | 1999 | Mol. Pharmacol. | pmid:10385693 |
| Maher M et al. | Activation of TRPA1 by farnesyl thiosalicylic acid. | 2008 | Mol. Pharmacol. | pmid:18171730 |
| Bandara HM et al. | Incorporation of Farnesol Significantly Increases the Efficacy of Liposomal Ciprofloxacin against Pseudomonas aeruginosa Biofilms in Vitro. | 2016 | Mol. Pharm. | pmid:27383205 |
| Zhang X et al. | PEG-farnesyl thiosalicylic acid telodendrimer micelles as an improved formulation for targeted delivery of paclitaxel. | 2014 | Mol. Pharm. | pmid:24987803 |
| Savoldi M et al. | Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase. | 2008 | Mol. Microbiol. | pmid:18681941 |
| Cugini C et al. | Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa. | 2007 | Mol. Microbiol. | pmid:17640272 |