8-iso-pge2 is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with 8-iso-PGE2
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Pre-Eclampsia | D011225 | 16 associated lipids |
| Premature Birth | D047928 | 6 associated lipids |
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mastalerz L et al. | Aspirin provocation increases 8-iso-PGE2 in exhaled breath condensate of aspirin-hypersensitive asthmatics. | 2015 | Prostaglandins Other Lipid Mediat. | pmid:26209241 |
| Shida T et al. | Fluvastatin-induced reduction of oxidative stress ameliorates diabetic cardiomyopathy in association with improving coronary microvasculature. | 2014 | Heart Vessels | pmid:23979266 |
| Chen JX et al. | Isoprostanes as physiological mediators of transition to newborn life: novel mechanisms regulating patency of the term and preterm ductus arteriosus. | 2012 | Pediatr. Res. | pmid:22565502 |
| Sakariassen KS et al. | EV-077 in vitro inhibits platelet aggregation in type-2 diabetics on aspirin. | 2012 | Thromb. Res. | pmid:22959706 |
| Singh B et al. | Partial inhibition of estrogen-induced mammary carcinogenesis in rats by tamoxifen: balance between oxidant stress and estrogen responsiveness. | 2011 | PLoS ONE | pmid:21966433 |
| Hausermann L and St-Louis J | Thromboxane and isoprostane share the same prostanoid receptors to increase human placental tone. | 2011 | Placenta | pmid:22015024 |
| Makino A et al. | Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes. | 2010 | Diabetologia | pmid:20461356 |
| Graham LS et al. | Oxidized lipids enhance RANKL production by T lymphocytes: implications for lipid-induced bone loss. | 2009 | Clin. Immunol. | pmid:19699688 |
| Navarrete CM et al. | Opposite effects of anandamide and N-arachidonoyl dopamine in the regulation of prostaglandin E and 8-iso-PGF formation in primary glial cells. | 2009 | J. Neurochem. | pmid:19200337 |
| Nielsen FH | Marginal zinc deficiency increases magnesium retention and impairs calcium utilization in rats. | 2009 | Biol Trace Elem Res | pmid:19002387 |
| Zhao M et al. | Role of prostanoid production and receptors in the regulation of retinal endogenous amino acid neurotransmitters by 8-isoprostaglandin E2, ex vivo. | 2009 | Neurochem. Res. | pmid:19513831 |
| Noschka E et al. | Thromboxane and isoprostanes as inflammatory and vasoactive mediators in black walnut heartwood extract induced equine laminitis. | 2009 | Vet. Immunol. Immunopathol. | pmid:19111354 |
| Friel AM et al. | Expression levels of mRNA for Rho A/Rho kinase and its role in isoprostane-induced vasoconstriction of human placental and maternal vessels. | 2008 | Reprod Sci | pmid:18089586 |
| Benndorf RA et al. | Isoprostanes inhibit vascular endothelial growth factor-induced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: a potential link between oxidative stress and impaired angiogenesis. | 2008 | Circ. Res. | pmid:18802021 |
| Zhao M et al. | Regulation of retinal morphology and posterior segment amino acids by 8-isoprostaglandin E2 in bovine eyes ex vivo. | 2008 | Methods Find Exp Clin Pharmacol | pmid:19088946 |
| Joy AP and Cowley EA | 8-iso-PGE2 stimulates anion efflux from airway epithelial cells via the EP4 prostanoid receptor. | 2008 | Am. J. Respir. Cell Mol. Biol. | pmid:17690331 |
| Friel AM et al. | Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction. | 2006 | Reproduction | pmid:16816342 |
| Daray FM et al. | Involvement of endothelial thromboxane A2 in the vasoconstrictor response induced by 15-E2t-isoprostane in isolated human umbilical vein. | 2006 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:16738877 |
| Morrow JD | The isoprostanes - unique products of arachidonate peroxidation: their role as mediators of oxidant stress. | 2006 | Curr. Pharm. Des. | pmid:16533158 |
| Badr KF and Abi-Antoun TE | Isoprostanes and the kidney. | 2005 Jan-Feb | Antioxid. Redox Signal. | pmid:15650411 |
| Zhang Y et al. | 8-isoprostaglandin E(2) activates Ca(2+)-dependent K(+) current via cyclic AMP signaling pathway in murine renal artery. | 2005 | Eur. J. Pharmacol. | pmid:16153635 |
| Fahlbusch SA et al. | Effects of carvedilol on oxidative stress in human endothelial cells and healthy volunteers. | 2004 | Eur. J. Clin. Pharmacol. | pmid:15004731 |
| Catalli A and Janssen LJ | Augmentation of bovine airway smooth muscle responsiveness to carbachol, KCl, and histamine by the isoprostane 8-iso-PGE2. | 2004 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:15257985 |
| Jefferson JA et al. | Increased oxidative stress following acute and chronic high altitude exposure. | 2004 | High Alt. Med. Biol. | pmid:15072717 |
| Gabelt BT et al. | Aqueous humor dynamics in monkeys after topical 8-iso PGE(2). | 2004 | Invest. Ophthalmol. Vis. Sci. | pmid:14985307 |
| Helli PB et al. | The bronchodilators 8-iso-prostaglandin E2 and prostaglandin E2 induce K+ current suppression via thromboxane A2 receptors in porcine tracheal smooth muscle. | 2004 | Eur. J. Pharmacol. | pmid:15464076 |
| Daray FM et al. | Vasoconstrictor effects of 8-iso-prostaglandin E2 and 8-iso-prostaglandin F(2alpha) on human umbilical vein. | 2004 | Eur. J. Pharmacol. | pmid:15363966 |
| Tazzeo T et al. | Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle. | 2003 | Br. J. Pharmacol. | pmid:14504139 |
| Brault S et al. | Selective neuromicrovascular endothelial cell death by 8-Iso-prostaglandin F2alpha: possible role in ischemic brain injury. | 2003 | Stroke | pmid:12624307 |
| Nakamura K et al. | Effects of 8-iso-prostaglandin E2 and 8-iso-prostaglandin F2 alpha on the release of noradrenaline from the isolated rat stomach. | 2003 | Eur. J. Pharmacol. | pmid:12787833 |
| Weber TJ and Markillie LM | Regulation of activator protein-1 by 8-iso-prostaglandin E2 in a thromboxane A2 receptor-dependent and -independent manner. | 2003 | Mol. Pharmacol. | pmid:12695536 |
| Huber J et al. | The isoprostane 8-iso-PGE2 stimulates endothelial cells to bind monocytes via cyclic AMP- and p38 MAP kinase-dependent signaling pathways. | 2003 | Antioxid. Redox Signal. | pmid:12716476 |
| Wood LG et al. | Improved antioxidant and fatty acid status of patients with cystic fibrosis after antioxidant supplementation is linked to improved lung function. | 2003 | Am. J. Clin. Nutr. | pmid:12499335 |
| Cowley EA | Isoprostane-mediated secretion from human airway epithelial cells. | 2003 | Mol. Pharmacol. | pmid:12869634 |
| Gao L et al. | Formation of prostaglandins E2 and D2 via the isoprostane pathway: a mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase. | 2003 | J. Biol. Chem. | pmid:12746435 |
| Zhang Y et al. | Vasodilatory and electrophysiological actions of 8-iso-prostaglandin E2 in porcine coronary artery. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12626646 |
| Tintut Y et al. | 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway. | 2002 | J. Biol. Chem. | pmid:11827970 |
| Wood LG et al. | Increased plasma fatty acid concentrations after respiratory exacerbations are associated with elevated oxidative stress in cystic fibrosis patients. | 2002 | Am. J. Clin. Nutr. | pmid:11916752 |
| Janssen LJ and Tazzeo T | Involvement of TP and EP3 receptors in vasoconstrictor responses to isoprostanes in pulmonary vasculature. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12023538 |
| Catalli A et al. | Receptors and signaling pathway underlying relaxations to isoprostanes in canine and porcine airway smooth muscle. | 2002 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12376370 |
| Unmack MA et al. | Effects of isoprostanes and prostanoids on porcine small intestine. | 2001 | J. Pharmacol. Exp. Ther. | pmid:11160628 |
| Cracowski JL et al. | Isoprostaglandin E2 type-III (8-iso-prostaglandin E2) evoked contractions in the human internal mammary artery. | 2001 | Life Sci. | pmid:11350011 |
| Serle JB et al. | Effect of pilocarpine 4% in combination with latanoprost 0.005% or 8-iso prostaglandin E2 0.1% on intraocular pressure in laser-induced glaucomatous monkey eyes. | 2001 | J. Glaucoma | pmid:11442186 |
| Junger H and Sorkin LS | Isoprostanes induce plasma extravasation in rat skin. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:11060897 |
| Sametz W et al. | Characterization of prostanoid receptors mediating actions of the isoprostanes, 8-iso-PGE(2) and 8-iso-PGF(2alpha), in some isolated smooth muscle preparations. | 2000 | Br. J. Pharmacol. | pmid:10952681 |
| Evans AR et al. | Isoprostanes, novel eicosanoids that produce nociception and sensitize rat sensory neurons. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10869392 |
| Wang RF et al. | Effect of latanoprost or 8-iso prostaglandin E2 alone and in combination on intraocular pressure in glaucomatous monkey eyes. | 2000 | Arch. Ophthalmol. | pmid:10636418 |
| Oliveira L et al. | Effects of some isoprostanes on the human umbilical artery in vitro. | 2000 | Br. J. Pharmacol. | pmid:10711349 |
| Junger H and Sorkin LS | C-nociceptor sensitization by isoprostanes is cyclooxygenase dependent. | 2000 | Brain Res. | pmid:10837823 |
| Janssen LJ et al. | Excitatory and inhibitory actions of isoprostanes in human and canine airway smooth muscle. | 2000 | J. Pharmacol. Exp. Ther. | pmid:11046082 |