Liu CI et al. |
Structural insights into the catalytic mechanism of human squalene synthase. |
2014 |
Acta Crystallogr. D Biol. Crystallogr. |
pmid:24531458
|
Smith R et al. |
Simvastatin inhibits glucose metabolism and legumain activity in human myotubes. |
2014 |
PLoS ONE |
pmid:24416446
|
Yang C et al. |
Simvastatin-enhanced expression of promyogenic nuclear factors and cardiomyogenesis of murine embryonic stem cells. |
2014 |
Vascul. Pharmacol. |
pmid:24200505
|
Wood WG et al. |
Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis. |
2014 |
J. Neurochem. |
pmid:24329875
|
Hartwig S et al. |
Expression, purification and activity assay of a patchoulol synthase cDNA variant fused to thioredoxin in Escherichia coli. |
2014 |
Protein Expr. Purif. |
pmid:24576659
|
Mabanglo MF et al. |
Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design. |
2014 |
Protein Sci. |
pmid:24347326
|
Du CQ et al. |
Inhibition of farnesyl pyrophosphate synthase prevents norepinephrine-induced fibrotic responses in vascular smooth muscle cells from spontaneously hypertensive rats. |
2014 |
Hypertens. Res. |
pmid:23985701
|
Gonzalez V et al. |
Evolutionary and mechanistic insights from the reconstruction of α-humulene synthases from a modern (+)-germacrene A synthase. |
2014 |
J. Am. Chem. Soc. |
pmid:25230152
|
Dozier JK et al. |
Engineering protein farnesyltransferase for enzymatic protein labeling applications. |
2014 |
Bioconjug. Chem. |
pmid:24946229
|
AlcaÃno J et al. |
Functional characterization of the Xanthophyllomyces dendrorhous farnesyl pyrophosphate synthase and geranylgeranyl pyrophosphate synthase encoding genes that are involved in the synthesis of isoprenoid precursors. |
2014 |
PLoS ONE |
pmid:24796858
|
Shang N et al. |
Squalene synthase as a target for Chagas disease therapeutics. |
2014 |
PLoS Pathog. |
pmid:24789335
|
Yokoyama T et al. |
Crystallization and preliminary neutron diffraction experiment of human farnesyl pyrophosphate synthase complexed with risedronate. |
2014 |
Acta Crystallogr F Struct Biol Commun |
pmid:24699741
|
Nyati P et al. |
Negative Feedbacks by Isoprenoids on a Mevalonate Kinase Expressed in the Corpora Allata of Mosquitoes. |
2015 |
PLoS ONE |
pmid:26566274
|
Henry LK et al. |
Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26216978
|
Sharon C et al. |
Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. |
2015 |
Oncotarget |
pmid:25895029
|
ElAzzouny MA et al. |
Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells. |
2015 |
PLoS ONE |
pmid:26107620
|
Ferriols VM et al. |
Cloning and characterization of farnesyl pyrophosphate synthase from the highly branched isoprenoid producing diatom Rhizosolenia setigera. |
2015 |
Sci Rep |
pmid:25996801
|
Harris GG et al. |
Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence. |
2015 |
Biochemistry |
pmid:26598179
|
Srivastava PL et al. |
Functional Characterization of Novel Sesquiterpene Synthases from Indian Sandalwood, Santalum album. |
2015 |
Sci Rep |
pmid:25976282
|
Rising KA et al. |
Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase. |
2015 |
ACS Chem. Biol. |
pmid:25897591
|