Shishova EY et al. |
X-ray crystallographic studies of substrate binding to aristolochene synthase suggest a metal ion binding sequence for catalysis. |
2008 |
J. Biol. Chem. |
pmid:18385128
|
Argmann CA et al. |
Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux. |
2005 |
J. Biol. Chem. |
pmid:15817453
|
Gonzalez-Pacanowska D et al. |
Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation. |
1988 |
J. Biol. Chem. |
pmid:3335546
|
SAMUELSSON B and GOODMAN DS |
STEREOCHEMISTRY AT THE CENTER OF SQUALENE DURING ITS BIOSYNTHESIS FROM FARNESYL PYROPHOSPHATE AND SUBSEQUENT CONVERSION TO CHOLESTEROL. |
1964 |
J. Biol. Chem. |
pmid:14114881
|
Guo RT et al. |
Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis. |
2005 |
J. Biol. Chem. |
pmid:15788389
|
POPJAK G et al. |
Studies on the biosynthesis of cholesterol. XV. Mechanism of squalene biosynthesis from farnesyl pyrophosphate and from mevalonate. |
1961 |
J. Biol. Chem. |
pmid:13737104
|
Kuswik-Rabiega G and Rilling HC |
Squalene synthetase. Solubilization and partial purification of squalene synthetase, copurification of presqualene pyrophosphate and squalene synthetase activities. |
1987 |
J. Biol. Chem. |
pmid:3805037
|
Reiss Y et al. |
Divalent cation and prenyl pyrophosphate specificities of the protein farnesyltransferase from rat brain, a zinc metalloenzyme. |
1992 |
J. Biol. Chem. |
pmid:1556143
|
Shechter I et al. |
Solubilization, purification, and characterization of a truncated form of rat hepatic squalene synthetase. |
1992 |
J. Biol. Chem. |
pmid:1569107
|
Ericsson J et al. |
Isoprenoid biosynthesis in rat liver peroxisomes. Characterization of cis-prenyltransferase and squalene synthetase. |
1992 |
J. Biol. Chem. |
pmid:1527001
|
Pickett JS et al. |
Mutagenesis studies of protein farnesyltransferase implicate aspartate beta 352 as a magnesium ligand. |
2003 |
J. Biol. Chem. |
pmid:14532266
|
Schaber MD et al. |
Polyisoprenylation of Ras in vitro by a farnesyl-protein transferase. |
1990 |
J. Biol. Chem. |
pmid:2203759
|
Reiss Y et al. |
Nonidentical subunits of p21H-ras farnesyltransferase. Peptide binding and farnesyl pyrophosphate carrier functions. |
1991 |
J. Biol. Chem. |
pmid:2037606
|
POPJAK G et al. |
Studies on the biosynthesis of cholesterol. XVI. Chemical synthesis of 1-H2-3-2-C-14- and 1-D2-2-C-14-trans-trans-farnesyl pyrophosphate and their utilization in squalene biosynthesis. |
1962 |
J. Biol. Chem. |
pmid:14487886
|
Garza RM et al. |
Geranylgeranyl pyrophosphate is a potent regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA reductase degradation in yeast. |
2009 |
J. Biol. Chem. |
pmid:19776008
|
Biardi L and Krisans SK |
Compartmentalization of cholesterol biosynthesis. Conversion of mevalonate to farnesyl diphosphate occurs in the peroxisomes. |
1996 |
J. Biol. Chem. |
pmid:8576183
|
Otto JC and Casey PJ |
The hepatitis delta virus large antigen is farnesylated both in vitro and in animal cells. |
1996 |
J. Biol. Chem. |
pmid:8617711
|
Kavanagh KL et al. |
The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding. |
2006 |
J. Biol. Chem. |
pmid:16698791
|
Tschantz WR et al. |
Substrate binding is required for release of product from mammalian protein farnesyltransferase. |
1997 |
J. Biol. Chem. |
pmid:9092540
|
Hartman HL et al. |
Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium. |
2004 |
J. Biol. Chem. |
pmid:15131129
|