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Farnesyl phosphates are endogenous ligands of lysophosphatidic acid receptors: inhibition of LPA GPCR and activation of PPARs. |
2006 |
Biochim. Biophys. Acta |
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Characterization and tissue-specific expression of two lepidopteran farnesyl diphosphate synthase homologs: implications for the biosynthesis of ethyl-substituted juvenile hormones. |
2006 |
Proteins |
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Simvastatin inhibits the migration and adhesion of monocytic cells and disorganizes the cytoskeleton of activated endothelial cells. |
2006 |
Eur. J. Pharmacol. |
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J. Antibiot. |
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2006 |
J. Am. Chem. Soc. |
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2006 |
Biochemistry |
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Hydrophilic anilinogeranyl diphosphate prenyl analogues are Ras function inhibitors. |
2006 |
Biochemistry |
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The products of a single maize sesquiterpene synthase form a volatile defense signal that attracts natural enemies of maize herbivores. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
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RhoA and p38 MAPK mediate apoptosis induced by cellular cholesterol depletion. |
2006 |
Apoptosis |
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Biochemical characterization of the decaprenyl diphosphate synthase of Rhodobacter sphaeroides for coenzyme Q10 production. |
2006 |
Appl. Microbiol. Biotechnol. |
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The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding. |
2006 |
J. Biol. Chem. |
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2006 |
Appl. Biochem. Biotechnol. |
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Tools to analyze protein farnesylation in cells. |
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Computational and conformational evaluation of FTase alternative substrates: insight into a novel enzyme binding pocket. |
2005 Jul-Aug |
J Chem Inf Model |
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Regulation of rubber biosynthetic rate and molecular weight in Hevea brasiliensis by metal cofactor. |
2005 Jan-Feb |
Biomacromolecules |
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Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption. |
2005 |
J. Med. Chem. |
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HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo. |
2005 |
Circulation |
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Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux. |
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J. Biol. Chem. |
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[Minodronic acid hydrate as a new therapeutic agent for osteoporosis]. |
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Clin Calcium |
pmid:15632466
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