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Cracking down on caveolin: role of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in modulating edothelial cell nitric oxide production. |
2001 |
Circulation |
pmid:11136674
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Raisig A and Sandmann G |
Functional properties of diapophytoene and related desaturases of C(30) and C(40) carotenoid biosynthetic pathways. |
2001 |
Biochim. Biophys. Acta |
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Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins). |
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Br. J. Pharmacol. |
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Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells. |
2001 |
Leukemia |
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Partial characterization of farnesyl and geranylgeranyl diphosphatases induced in rice seedlings by UV-C irradiation. |
2001 |
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Bisphosphonates are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase. |
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J. Biol. Chem. |
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Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition. |
2001 |
Mol. Cell. Neurosci. |
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Study on the biosynthesis of dolichol in yeast: recognition of the prenyl chain length in polyprenol reduction. |
2001 |
J. Biochem. |
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Structural features of nonpeptide prenyl pyrophosphates that determine their antigenicity for human gamma delta T cells. |
2001 |
J. Immunol. |
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Amorpha-4,11-diene synthase of Artemisia annua: cDNA isolation and bacterial expression of a terpene synthase involved in artemisinin biosynthesis. |
2000 |
Arch. Biochem. Biophys. |
pmid:11185551
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Metabolism of farnesyl diphosphate in tobacco BY-2 cells treated with squalestatin. |
2000 |
Biochem. Soc. Trans. |
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Compactin suppresses bone resorption by inhibiting the fusion of prefusion osteoclasts and disrupting the actin ring in osteoclasts. |
2000 |
J. Bone Miner. Res. |
pmid:10780857
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Geranylgeranyl-pyrophosphate, an isoprenoid of mevalonate cascade, is a critical compound for rat primary cultured cortical neurons to protect the cell death induced by 3-hydroxy-3-methylglutaryl-CoA reductase inhibition. |
2000 |
J. Neurosci. |
pmid:10751437
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Molecular cloning, expression, and characterization of amorpha-4,11-diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L. |
2000 |
Arch. Biochem. Biophys. |
pmid:11032404
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Involvement of Rho GTPases in the transcriptional inhibition of preproendothelin-1 gene expression by simvastatin in vascular endothelial cells. |
2000 |
Circ. Res. |
pmid:11009568
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Phosphoisoprenoid binding specificity of geranylgeranyltransferase type II. |
2000 |
Biochemistry |
pmid:11009619
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Simvastatin modulates cytokine-mediated endothelial cell adhesion molecule induction: involvement of an inhibitory G protein. |
2000 |
J. Immunol. |
pmid:10946302
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Grignard-mediated synthesis and preliminary biological evaluation of novel 3-substituted farnesyl diphosphate analogues. |
2000 |
Bioorg. Med. Chem. Lett. |
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Purification and characterization of mevalonate kinase from suspension-cultured cells of Catharanthus roseus (L.) G. Don. |
2000 |
Arch. Biochem. Biophys. |
pmid:10860546
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Zhang YW et al. |
Chain length determination of prenyltransferases: both heteromeric subunits of medium-chain (E)-prenyl diphosphate synthase are involved in the product chain length determination. |
2000 |
Biochemistry |
pmid:11027152
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