| Sasiak K and Rilling HC |
Purification to homogeneity and some properties of squalene synthetase. |
1988 |
Arch. Biochem. Biophys. |
pmid:3277535
|
| Bruenger E and Rilling HC |
Determination of isopentenyl diphosphate and farnesyl diphosphate in tissue samples with a comment on secondary regulation of polyisoprenoid biosynthesis. |
1988 |
Anal. Biochem. |
pmid:3189812
|
| Biller SA et al. |
Isoprenoid (phosphinylmethyl)phosphonates as inhibitors of squalene synthetase. |
1988 |
J. Med. Chem. |
pmid:3172121
|
| Croteau R et al. |
Biosynthesis of the sesquiterpene patchoulol from farnesyl pyrophosphate in leaf extracts of Pogostemon cablin (patchouli): mechanistic considerations. |
1987 |
Arch. Biochem. Biophys. |
pmid:3038029
|
| Sagami H et al. |
The biosynthesis of dehydrodolichyl phosphates by rat liver microsomes. |
1989 |
Biochim. Biophys. Acta |
pmid:2930770
|
|
|
|
|
pmid:28813599
|
|
|
|
|
pmid:28695386
|
|
|
|
|
pmid:28559264
|
|
|
|
|
pmid:28547322
|
|
|
|
|
pmid:28478108
|
|
|
|
|
pmid:28371548
|
| Mendez-Perez D et al. |
Production of jet fuel precursor monoterpenoids from engineered Escherichia coli. |
2017 |
Biotechnol. Bioeng. |
pmid:28369701
|
|
|
|
|
pmid:28343347
|
| Agabiti SS et al. |
Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation. |
2017 |
Cell Death Dis |
pmid:28300835
|
| Kosek V et al. |
High resolution mass spectrometry based method applicable for a wide range of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors in blood serum including intermediates and products of the cholesterol biosynthetic pathway. |
2017 |
J Chromatogr A |
pmid:28209347
|
| Qian J et al. |
Positive selection and functional divergence of farnesyl pyrophosphate synthase genes in plants. |
2017 |
BMC Mol. Biol. |
pmid:28160774
|
| Light DR et al. |
Rubber elongation by farnesyl pyrophosphate synthases involves a novel switch in enzyme stereospecificity. |
1989 |
J. Biol. Chem. |
pmid:2808389
|
| Light DR and Dennis MS |
Purification of a prenyltransferase that elongates cis-polyisoprene rubber from the latex of Hevea brasiliensis. |
1989 |
J. Biol. Chem. |
pmid:2808388
|
|
|
|
|
pmid:28057800
|
|
|
|
|
pmid:27939849
|
|
|
|
|
pmid:27933789
|
| Wong MJ et al. |
Simvastatin prevents and reverses chronic pulmonary hypertension in newborn rats via pleiotropic inhibition of RhoA signaling. |
2016 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:27694473
|
|
|
|
|
pmid:27561253
|
|
|
|
|
pmid:27560952
|
|
|
|
|
pmid:27471067
|
|
|
|
|
pmid:27440491
|
|
|
|
|
pmid:27428767
|
| Yang J et al. |
Alteration of RhoA Prenylation Ameliorates Cardiac and Vascular Remodeling in Spontaneously Hypertensive Rats. |
2016 |
Cell. Physiol. Biochem. |
pmid:27336844
|
| Croteau R and Purkett PT |
Geranyl pyrophosphate synthase: characterization of the enzyme and evidence that this chain-length specific prenyltransferase is associated with monoterpene biosynthesis in sage (Salvia officinalis). |
1989 |
Arch. Biochem. Biophys. |
pmid:2730002
|
|
|
|
|
pmid:27273626
|
| Terabe K et al. |
Simvastatin inhibits CD44 fragmentation in chondrocytes. |
2016 |
Arch. Biochem. Biophys. |
pmid:27242325
|
|
|
|
|
pmid:27231873
|
|
|
|
|
pmid:27042994
|
|
|
|
|
pmid:27005818
|
| Grundy DJ et al. |
Mechanism of Germacradien-4-ol Synthase-Controlled Water Capture. |
2016 |
Biochemistry |
pmid:26998816
|
| Matsumoto Y et al. |
A critical role of mevalonate for peptidoglycan synthesis in Staphylococcus aureus. |
2016 |
Sci Rep |
pmid:26961421
|
|
|
|
|
pmid:26920719
|
| Pastar I et al. |
Skin Metabolite, Farnesyl Pyrophosphate, Regulates Epidermal Response to Inflammation, Oxidative Stress, and Migration. |
2016 |
J. Cell. Physiol. |
pmid:26916741
|
|
|
|
|
pmid:26908642
|
|
|
|
|
pmid:26873186
|
| Jennings BC et al. |
Analogs of farnesyl diphosphate alter CaaX substrate specificity and reactions rates of protein farnesyltransferase. |
2016 |
Bioorg. Med. Chem. Lett. |
pmid:26803203
|
|
|
|
|
pmid:26781029
|
| Fujisaki S et al. |
Isolation and characterization of an Escherichia coli mutant having temperature-sensitive farnesyl diphosphate synthase. |
1989 |
J. Bacteriol. |
pmid:2676985
|
|
|
|
|
pmid:26758949
|
|
|
|
|
pmid:26757191
|
|
|
|
|
pmid:26756303
|
| Pant A and Kocarek TA |
Role of Phosphatidic Acid Phosphatase Domain Containing 2 in Squalestatin 1-Mediated Activation of the Constitutive Androstane Receptor in Primary Cultured Rat Hepatocytes. |
2016 |
Drug Metab. Dispos. |
pmid:26700959
|
|
|
|
|
pmid:26626450
|
|
|
|
|
pmid:26610064
|
| Harris GG et al. |
Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence. |
2015 |
Biochemistry |
pmid:26598179
|
| Nyati P et al. |
Negative Feedbacks by Isoprenoids on a Mevalonate Kinase Expressed in the Corpora Allata of Mosquitoes. |
2015 |
PLoS ONE |
pmid:26566274
|
|
|
|
|
pmid:26556845
|
|
|
|
|
pmid:26361082
|
| Henry LK et al. |
Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26216978
|
| ElAzzouny MA et al. |
Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells. |
2015 |
PLoS ONE |
pmid:26107620
|
|
|
|
|
pmid:26051402
|
| Ferriols VM et al. |
Cloning and characterization of farnesyl pyrophosphate synthase from the highly branched isoprenoid producing diatom Rhizosolenia setigera. |
2015 |
Sci Rep |
pmid:25996801
|
| Srivastava PL et al. |
Functional Characterization of Novel Sesquiterpene Synthases from Indian Sandalwood, Santalum album. |
2015 |
Sci Rep |
pmid:25976282
|
|
|
|
|
pmid:25940560
|
| Rising KA et al. |
Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase. |
2015 |
ACS Chem. Biol. |
pmid:25897591
|
| Sharon C et al. |
Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. |
2015 |
Oncotarget |
pmid:25895029
|
|
|
|
|
pmid:25822613
|
|
|
|
|
pmid:25807032
|
|
|
|
|
pmid:25739905
|
|
|
|
|
pmid:25734506
|
|
|
|
|
pmid:25701786
|
|
|
|
|
pmid:25698327
|
|
|
|
|
pmid:25680349
|
|
|
|
|
pmid:25658388
|
|
|
|
|
pmid:25631750
|
|
|
|
|
pmid:25475893
|
|
|
|
|
pmid:25472483
|
| Hohn TM and Plattner RD |
Purification and characterization of the sesquiterpene cyclase aristolochene synthase from Penicillium roqueforti. |
1989 |
Arch. Biochem. Biophys. |
pmid:2544140
|
| Yoshida I et al. |
Formation of a stable and catalytically active complex of the two essential components of hexaprenyl diphosphate synthase from Micrococcus luteus B-P 26. |
1989 |
Biochem. Biophys. Res. Commun. |
pmid:2541701
|
| Yoshida I et al. |
Protection of hexaprenyl-diphosphate synthase of Micrococcus luteus B-P 26 against inactivation by sulphydryl reagents and arginine-specific reagents. |
1989 |
Biochim. Biophys. Acta |
pmid:2539196
|
| Danley DE et al. |
Discovery and structural characterization of an allosteric inhibitor of bacterial cis-prenyltransferase. |
2015 |
Protein Sci. |
pmid:25287857
|
| Gonzalez V et al. |
Evolutionary and mechanistic insights from the reconstruction of α-humulene synthases from a modern (+)-germacrene A synthase. |
2014 |
J. Am. Chem. Soc. |
pmid:25230152
|
|
|
|
|
pmid:25159317
|
|
|
|
|
pmid:25056927
|
|
|
|
|
pmid:25027024
|
|
|
|
|
pmid:24996285
|
| Dozier JK et al. |
Engineering protein farnesyltransferase for enzymatic protein labeling applications. |
2014 |
Bioconjug. Chem. |
pmid:24946229
|
|
|
|
|
pmid:24910970
|
| Han X et al. |
Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms. |
2015 |
Proteins |
pmid:24895191
|
|
|
|
|
pmid:24809278
|
| AlcaÃno J et al. |
Functional characterization of the Xanthophyllomyces dendrorhous farnesyl pyrophosphate synthase and geranylgeranyl pyrophosphate synthase encoding genes that are involved in the synthesis of isoprenoid precursors. |
2014 |
PLoS ONE |
pmid:24796858
|
| Shang N et al. |
Squalene synthase as a target for Chagas disease therapeutics. |
2014 |
PLoS Pathog. |
pmid:24789335
|
|
|
|
|
pmid:24762323
|
| Yokoyama T et al. |
Crystallization and preliminary neutron diffraction experiment of human farnesyl pyrophosphate synthase complexed with risedronate. |
2014 |
Acta Crystallogr F Struct Biol Commun |
pmid:24699741
|
|
|
|
|
pmid:24692239
|
| Hartwig S et al. |
Expression, purification and activity assay of a patchoulol synthase cDNA variant fused to thioredoxin in Escherichia coli. |
2014 |
Protein Expr. Purif. |
pmid:24576659
|
| Liu CI et al. |
Structural insights into the catalytic mechanism of human squalene synthase. |
2014 |
Acta Crystallogr. D Biol. Crystallogr. |
pmid:24531458
|
|
|
|
|
pmid:24430210
|
| Smith R et al. |
Simvastatin inhibits glucose metabolism and legumain activity in human myotubes. |
2014 |
PLoS ONE |
pmid:24416446
|
| Mabanglo MF et al. |
Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design. |
2014 |
Protein Sci. |
pmid:24347326
|
| Wood WG et al. |
Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis. |
2014 |
J. Neurochem. |
pmid:24329875
|
| Wang H et al. |
Studies on the expression of sesquiterpene synthases using promoter-β-glucuronidase fusions in transgenic Artemisia annua L. |
2013 |
PLoS ONE |
pmid:24278301
|
| Chen X et al. |
Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene. |
2013 |
PLoS ONE |
pmid:24278153
|
| Nowroozi FF et al. |
Metabolic pathway optimization using ribosome binding site variants and combinatorial gene assembly. |
2014 |
Appl. Microbiol. Biotechnol. |
pmid:24257840
|
| Burgazli KM et al. |
The effects of different types of statins on proliferation and migration of HGF-induced Human Umbilical Vein Endothelial Cells (HUVECs). |
2013 |
Eur Rev Med Pharmacol Sci |
pmid:24254555
|
