Mann FM et al. |
Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis. |
2011 |
FEBS Lett. |
pmid:21237161
|
Weivoda MM and Hohl RJ |
Effects of farnesyl pyrophosphate accumulation on calvarial osteoblast differentiation. |
2011 |
Endocrinology |
pmid:21586555
|
Dong X et al. |
Quantitative proteomic analysis revealed lovastatin-induced perturbation of cellular pathways in HL-60 cells. |
2011 |
J. Proteome Res. |
pmid:21967149
|
Cluis CP et al. |
Identification of bottlenecks in Escherichia coli engineered for the production of CoQ(10). |
2011 |
Metab. Eng. |
pmid:21986057
|
Sasaki D et al. |
Crystal structure of heterodimeric hexaprenyl diphosphate synthase from Micrococcus luteus B-P 26 reveals that the small subunit is directly involved in the product chain length regulation. |
2011 |
J. Biol. Chem. |
pmid:21068379
|
Holstein SA et al. |
Pleiotropic effects of a schweinfurthin on isoprenoid homeostasis. |
2011 |
Lipids |
pmid:21633866
|
Hu Y et al. |
Genome mining in Streptomyces clavuligerus: expression and biochemical characterization of two new cryptic sesquiterpene synthases. |
2011 |
Chem. Biol. |
pmid:21276937
|
Cazzola M et al. |
Protein prenylation contributes to the effects of LPS on EFS-induced responses in human isolated bronchi. |
2011 |
Am. J. Respir. Cell Mol. Biol. |
pmid:21278325
|
Bang S et al. |
Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels. |
2011 |
Pain |
pmid:21353389
|
Von Zee CL and Stubbs EB |
Geranylgeranylation facilitates proteasomal degradation of rho G-proteins in human trabecular meshwork cells. |
2011 |
Invest. Ophthalmol. Vis. Sci. |
pmid:21212187
|
Goto T et al. |
Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. |
2011 |
Biochem. J. |
pmid:21605082
|
Wong DH et al. |
Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells. |
2011 |
Fertil. Steril. |
pmid:21907337
|
Brown AJ |
Isoprenoid is a perfect fit for fat factor. |
2011 |
Biochem. J. |
pmid:21793802
|
Schaafsma D et al. |
Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. |
2011 |
Respir. Res. |
pmid:21864337
|
Leichner GS et al. |
Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein. |
2011 |
J. Biol. Chem. |
pmid:21778231
|
Wasko BM et al. |
A novel bisphosphonate inhibitor of squalene synthase combined with a statin or a nitrogenous bisphosphonate in vitro. |
2011 |
J. Lipid Res. |
pmid:21903868
|
Pani A et al. |
Computational identification of sweet wormwood (Artemisia annua) microRNA and their mRNA targets. |
2011 |
Genomics Proteomics Bioinformatics |
pmid:22289476
|
Wang C et al. |
Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway. |
2010 |
Biotechnol. Bioeng. |
pmid:20552672
|
Vukelic S et al. |
Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor. |
2010 |
J. Biol. Chem. |
pmid:19903814
|
Lu YP et al. |
Mechanism of cis-prenyltransferase reaction probed by substrate analogues. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20828539
|
Koohang A et al. |
Enantioselective inhibition of squalene synthase by aziridine analogues of presqualene diphosphate. |
2010 |
J. Org. Chem. |
pmid:20545375
|
Holstein SA et al. |
Differential activities of thalidomide and isoprenoid biosynthetic pathway inhibitors in multiple myeloma cells. |
2010 |
Leuk. Res. |
pmid:19646757
|
Hooff GP et al. |
A rapid and sensitive assay for determining human brain levels of farnesyl-(FPP) and geranylgeranylpyrophosphate (GGPP) and transferase activities using UHPLC-MS/MS. |
2010 |
Anal Bioanal Chem |
pmid:20730526
|
Goyanka R et al. |
Nuclear receptor engineering based on novel structure activity relationships revealed by farnesyl pyrophosphate. |
2010 |
Protein Eng. Des. Sel. |
pmid:20817759
|
Adams VR et al. |
Anticancer activity of novel unnatural synthetic isoprenoids. |
2010 |
Anticancer Res. |
pmid:20682975
|
Rojruthai P et al. |
In vitro synthesis of high molecular weight rubber by Hevea small rubber particles. |
2010 |
J. Biosci. Bioeng. |
pmid:20129092
|
Schmidt A et al. |
A bifunctional geranyl and geranylgeranyl diphosphate synthase is involved in terpene oleoresin formation in Picea abies. |
2010 |
Plant Physiol. |
pmid:19939949
|
Singkaravanit S et al. |
Geranylgeranyl diphosphate synthase genes in entomopathogenic fungi. |
2010 |
Appl. Microbiol. Biotechnol. |
pmid:19690851
|
Kato S et al. |
Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase. |
2010 |
J. Cell. Mol. Med. |
pmid:19432822
|
Faraldos JA et al. |
Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate. |
2010 |
J. Am. Chem. Soc. |
pmid:20201526
|
Bang S et al. |
Farnesyl pyrophosphate is a novel pain-producing molecule via specific activation of TRPV3. |
2010 |
J. Biol. Chem. |
pmid:20395302
|
Hooff GP et al. |
Modulation of cholesterol, farnesylpyrophosphate, and geranylgeranylpyrophosphate in neuroblastoma SH-SY5Y-APP695 cells: impact on amyloid beta-protein production. |
2010 |
Mol. Neurobiol. |
pmid:20405344
|
Schramek N et al. |
Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study. |
2010 |
Phytochemistry |
pmid:19932496
|
Hovlid ML et al. |
Synthesis, properties, and applications of diazotrifluropropanoyl-containing photoactive analogs of farnesyl diphosphate containing modified linkages for enhanced stability. |
2010 |
Chem Biol Drug Des |
pmid:19954434
|
Woo IS et al. |
Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells. |
2010 |
Neurosci. Lett. |
pmid:20298756
|
Chou WK et al. |
Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol. |
2010 |
J. Am. Chem. Soc. |
pmid:20536237
|
Willot M and Christmann M |
Total synthesis: towards artificial terpene cyclases. |
2010 |
Nat Chem |
pmid:20571563
|
Lee SH et al. |
Distribution of endogenous farnesyl pyrophosphate and four species of lysophosphatidic acid in rodent brain. |
2010 |
Int J Mol Sci |
pmid:21152313
|
Faraldos JA et al. |
Doubly deuterium-labeled patchouli alcohol from cyclization of singly labeled [2-(2)H(1)]farnesyl diphosphate catalyzed by recombinant patchoulol synthase. |
2010 |
J. Am. Chem. Soc. |
pmid:20148554
|
Morofuji Y et al. |
Pitavastatin strengthens the barrier integrity in primary cultures of rat brain endothelial cells. |
2010 |
Cell. Mol. Neurobiol. |
pmid:20127168
|
Asadollahi MA et al. |
Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae. |
2010 |
Biotechnol. Bioeng. |
pmid:20091767
|
Miriyala S et al. |
Functional characterization of the atypical integral membrane lipid phosphatase PDP1/PPAPDC2 identifies a pathway for interconversion of isoprenols and isoprenoid phosphates in mammalian cells. |
2010 |
J. Biol. Chem. |
pmid:20110354
|
Duez S et al. |
Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues. |
2010 |
Bioorg. Med. Chem. |
pmid:20036564
|
Lopez-Gallego F et al. |
Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers. |
2010 |
Chembiochem |
pmid:20419721
|
Lee SK et al. |
Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20043868
|
Uchida H et al. |
Cloning and characterization of a squalene synthase gene from a petroleum plant, Euphorbia tirucalli L. |
2009 |
Planta |
pmid:19283408
|
Holstein SA et al. |
Quantitative determination of geranyl diphosphate levels in cultured human cells. |
2009 |
Lipids |
pmid:19856009
|
Lu YP et al. |
Different reaction mechanisms for cis- and trans-prenyltransferases. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19103164
|
Sillero MA et al. |
Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts. |
2009 |
Biochem. Pharmacol. |
pmid:19414000
|
Zhao B et al. |
Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site. |
2009 |
J. Biol. Chem. |
pmid:19858213
|