Mann FM et al. |
Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis. |
2011 |
FEBS Lett. |
pmid:21237161
|
Dong X et al. |
Quantitative proteomic analysis revealed lovastatin-induced perturbation of cellular pathways in HL-60 cells. |
2011 |
J. Proteome Res. |
pmid:21967149
|
Cluis CP et al. |
Identification of bottlenecks in Escherichia coli engineered for the production of CoQ(10). |
2011 |
Metab. Eng. |
pmid:21986057
|
Nakano C et al. |
Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus. |
2011 |
J. Biol. Chem. |
pmid:21693706
|
Placzek AT and Gibbs RA |
New synthetic methodology for the construction of 7-substituted farnesyl diphosphate analogs. |
2011 |
Org. Lett. |
pmid:21699139
|
Holstein SA et al. |
Pleiotropic effects of a schweinfurthin on isoprenoid homeostasis. |
2011 |
Lipids |
pmid:21633866
|
Hu Y et al. |
Genome mining in Streptomyces clavuligerus: expression and biochemical characterization of two new cryptic sesquiterpene synthases. |
2011 |
Chem. Biol. |
pmid:21276937
|
Cazzola M et al. |
Protein prenylation contributes to the effects of LPS on EFS-induced responses in human isolated bronchi. |
2011 |
Am. J. Respir. Cell Mol. Biol. |
pmid:21278325
|
Von Zee CL and Stubbs EB |
Geranylgeranylation facilitates proteasomal degradation of rho G-proteins in human trabecular meshwork cells. |
2011 |
Invest. Ophthalmol. Vis. Sci. |
pmid:21212187
|
Goto T et al. |
Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. |
2011 |
Biochem. J. |
pmid:21605082
|
Clastre M et al. |
Subcellular evidence for the involvement of peroxisomes in plant isoprenoid biosynthesis. |
2011 |
Plant Signal Behav |
pmid:22080790
|
Schmidt A et al. |
Induction of isoprenyl diphosphate synthases, plant hormones and defense signalling genes correlates with traumatic resin duct formation in Norway spruce (Picea abies). |
2011 |
Plant Mol. Biol. |
pmid:22002747
|
Brown AJ |
Isoprenoid is a perfect fit for fat factor. |
2011 |
Biochem. J. |
pmid:21793802
|
Schaafsma D et al. |
Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. |
2011 |
Respir. Res. |
pmid:21864337
|
Leichner GS et al. |
Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein. |
2011 |
J. Biol. Chem. |
pmid:21778231
|
Wasko BM et al. |
A novel bisphosphonate inhibitor of squalene synthase combined with a statin or a nitrogenous bisphosphonate in vitro. |
2011 |
J. Lipid Res. |
pmid:21903868
|
Pani A et al. |
Computational identification of sweet wormwood (Artemisia annua) microRNA and their mRNA targets. |
2011 |
Genomics Proteomics Bioinformatics |
pmid:22289476
|
Wang C et al. |
Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway. |
2010 |
Biotechnol. Bioeng. |
pmid:20552672
|
Vukelic S et al. |
Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor. |
2010 |
J. Biol. Chem. |
pmid:19903814
|
Lu YP et al. |
Mechanism of cis-prenyltransferase reaction probed by substrate analogues. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20828539
|
Koohang A et al. |
Enantioselective inhibition of squalene synthase by aziridine analogues of presqualene diphosphate. |
2010 |
J. Org. Chem. |
pmid:20545375
|
Holstein SA et al. |
Differential activities of thalidomide and isoprenoid biosynthetic pathway inhibitors in multiple myeloma cells. |
2010 |
Leuk. Res. |
pmid:19646757
|
Hooff GP et al. |
A rapid and sensitive assay for determining human brain levels of farnesyl-(FPP) and geranylgeranylpyrophosphate (GGPP) and transferase activities using UHPLC-MS/MS. |
2010 |
Anal Bioanal Chem |
pmid:20730526
|
Goyanka R et al. |
Nuclear receptor engineering based on novel structure activity relationships revealed by farnesyl pyrophosphate. |
2010 |
Protein Eng. Des. Sel. |
pmid:20817759
|
Adams VR et al. |
Anticancer activity of novel unnatural synthetic isoprenoids. |
2010 |
Anticancer Res. |
pmid:20682975
|
Rojruthai P et al. |
In vitro synthesis of high molecular weight rubber by Hevea small rubber particles. |
2010 |
J. Biosci. Bioeng. |
pmid:20129092
|
Schmidt A et al. |
A bifunctional geranyl and geranylgeranyl diphosphate synthase is involved in terpene oleoresin formation in Picea abies. |
2010 |
Plant Physiol. |
pmid:19939949
|
Singkaravanit S et al. |
Geranylgeranyl diphosphate synthase genes in entomopathogenic fungi. |
2010 |
Appl. Microbiol. Biotechnol. |
pmid:19690851
|
Kato S et al. |
Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase. |
2010 |
J. Cell. Mol. Med. |
pmid:19432822
|
Faraldos JA et al. |
Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate. |
2010 |
J. Am. Chem. Soc. |
pmid:20201526
|
Bang S et al. |
Farnesyl pyrophosphate is a novel pain-producing molecule via specific activation of TRPV3. |
2010 |
J. Biol. Chem. |
pmid:20395302
|
Hooff GP et al. |
Modulation of cholesterol, farnesylpyrophosphate, and geranylgeranylpyrophosphate in neuroblastoma SH-SY5Y-APP695 cells: impact on amyloid beta-protein production. |
2010 |
Mol. Neurobiol. |
pmid:20405344
|
Schramek N et al. |
Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study. |
2010 |
Phytochemistry |
pmid:19932496
|
Hovlid ML et al. |
Synthesis, properties, and applications of diazotrifluropropanoyl-containing photoactive analogs of farnesyl diphosphate containing modified linkages for enhanced stability. |
2010 |
Chem Biol Drug Des |
pmid:19954434
|
Woo IS et al. |
Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells. |
2010 |
Neurosci. Lett. |
pmid:20298756
|
Chou WK et al. |
Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol. |
2010 |
J. Am. Chem. Soc. |
pmid:20536237
|
Willot M and Christmann M |
Total synthesis: towards artificial terpene cyclases. |
2010 |
Nat Chem |
pmid:20571563
|
Lee SH et al. |
Distribution of endogenous farnesyl pyrophosphate and four species of lysophosphatidic acid in rodent brain. |
2010 |
Int J Mol Sci |
pmid:21152313
|
Faraldos JA et al. |
Doubly deuterium-labeled patchouli alcohol from cyclization of singly labeled [2-(2)H(1)]farnesyl diphosphate catalyzed by recombinant patchoulol synthase. |
2010 |
J. Am. Chem. Soc. |
pmid:20148554
|
Morofuji Y et al. |
Pitavastatin strengthens the barrier integrity in primary cultures of rat brain endothelial cells. |
2010 |
Cell. Mol. Neurobiol. |
pmid:20127168
|
Asadollahi MA et al. |
Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae. |
2010 |
Biotechnol. Bioeng. |
pmid:20091767
|
Miriyala S et al. |
Functional characterization of the atypical integral membrane lipid phosphatase PDP1/PPAPDC2 identifies a pathway for interconversion of isoprenols and isoprenoid phosphates in mammalian cells. |
2010 |
J. Biol. Chem. |
pmid:20110354
|
Duez S et al. |
Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues. |
2010 |
Bioorg. Med. Chem. |
pmid:20036564
|
Lopez-Gallego F et al. |
Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers. |
2010 |
Chembiochem |
pmid:20419721
|
Lee SK et al. |
Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20043868
|
Rzepczynska IJ et al. |
Role of isoprenylation in simvastatin-induced inhibition of ovarian theca-interstitial growth in the rat. |
2009 |
Biol. Reprod. |
pmid:19571257
|
Coudray L et al. |
Synthesis of imidazole-containing analogues of farnesyl pyrophosphate and evaluation of their biological activity on protein farnesyltransferase. |
2009 |
J Enzyme Inhib Med Chem |
pmid:19555171
|
Harada H and Misawa N |
Novel approaches and achievements in biosynthesis of functional isoprenoids in Escherichia coli. |
2009 |
Appl. Microbiol. Biotechnol. |
pmid:19672590
|
Kim SE et al. |
Simvastatin inhibits induction of matrix metalloproteinase-9 in rat alveolar macrophages exposed to cigarette smoke extract. |
2009 |
Exp. Mol. Med. |
pmid:19299917
|
Zhao B et al. |
Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site. |
2009 |
J. Biol. Chem. |
pmid:19858213
|