Shishova EY et al. |
X-ray crystallographic studies of substrate binding to aristolochene synthase suggest a metal ion binding sequence for catalysis. |
2008 |
J. Biol. Chem. |
pmid:18385128
|
Gardner RG and Hampton RY |
A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes. |
1999 |
J. Biol. Chem. |
pmid:10531376
|
Argmann CA et al. |
Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux. |
2005 |
J. Biol. Chem. |
pmid:15817453
|
Hayes JS et al. |
The prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling. |
1999 |
J. Biol. Chem. |
pmid:10446129
|
Lindsey S and Harwood HJ |
Inhibition of mammalian squalene synthetase activity by zaragozic acid A is a result of competitive inhibition followed by mechanism-based irreversible inactivation. |
1995 |
J. Biol. Chem. |
pmid:7721822
|
Murthy S et al. |
Regulation of fatty acid synthesis by farnesyl pyrophosphate. |
2005 |
J. Biol. Chem. |
pmid:16221687
|
Gonzalez-Pacanowska D et al. |
Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation. |
1988 |
J. Biol. Chem. |
pmid:3335546
|
SAMUELSSON B and GOODMAN DS |
STEREOCHEMISTRY AT THE CENTER OF SQUALENE DURING ITS BIOSYNTHESIS FROM FARNESYL PYROPHOSPHATE AND SUBSEQUENT CONVERSION TO CHOLESTEROL. |
1964 |
J. Biol. Chem. |
pmid:14114881
|
POPJAK G et al. |
Studies on the biosynthesis of cholesterol. XV. Mechanism of squalene biosynthesis from farnesyl pyrophosphate and from mevalonate. |
1961 |
J. Biol. Chem. |
pmid:13737104
|
Ling Y et al. |
The farnesyl-diphosphate/geranylgeranyl-diphosphate synthase of Toxoplasma gondii is a bifunctional enzyme and a molecular target of bisphosphonates. |
2007 |
J. Biol. Chem. |
pmid:17724033
|
Vukelic S et al. |
Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor. |
2010 |
J. Biol. Chem. |
pmid:19903814
|
Lutz RJ et al. |
Feedback inhibition of polyisoprenyl pyrophosphate synthesis from mevalonate in vitro. Implications for protein prenylation. |
1992 |
J. Biol. Chem. |
pmid:1569056
|
Tanaka RD et al. |
Purification and regulation of mevalonate kinase from rat liver. |
1990 |
J. Biol. Chem. |
pmid:2153681
|
Faulkner A et al. |
The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae. |
1999 |
J. Biol. Chem. |
pmid:10329682
|
Mookhtiar KA et al. |
Yeast squalene synthase. A mechanism for addition of substrates and activation by NADPH. |
1994 |
J. Biol. Chem. |
pmid:8157649
|
Reiss Y et al. |
Divalent cation and prenyl pyrophosphate specificities of the protein farnesyltransferase from rat brain, a zinc metalloenzyme. |
1992 |
J. Biol. Chem. |
pmid:1556143
|
Pickett JS et al. |
Mutagenesis studies of protein farnesyltransferase implicate aspartate beta 352 as a magnesium ligand. |
2003 |
J. Biol. Chem. |
pmid:14532266
|
Reiss Y et al. |
Nonidentical subunits of p21H-ras farnesyltransferase. Peptide binding and farnesyl pyrophosphate carrier functions. |
1991 |
J. Biol. Chem. |
pmid:2037606
|
POPJAK G et al. |
Studies on the biosynthesis of cholesterol. XVI. Chemical synthesis of 1-H2-3-2-C-14- and 1-D2-2-C-14-trans-trans-farnesyl pyrophosphate and their utilization in squalene biosynthesis. |
1962 |
J. Biol. Chem. |
pmid:14487886
|
Montalvetti A et al. |
Bisphosphonates are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase. |
2001 |
J. Biol. Chem. |
pmid:11435429
|
Wagner PD and Vu ND |
Phosphorylation of geranyl and farnesyl pyrophosphates by Nm23 proteins/nucleoside diphosphate kinases. |
2000 |
J. Biol. Chem. |
pmid:10952986
|
Sasaki D et al. |
Crystal structure of heterodimeric hexaprenyl diphosphate synthase from Micrococcus luteus B-P 26 reveals that the small subunit is directly involved in the product chain length regulation. |
2011 |
J. Biol. Chem. |
pmid:21068379
|
Engels B et al. |
Cloning and characterization of an Armillaria gallica cDNA encoding protoilludene synthase, which catalyzes the first committed step in the synthesis of antimicrobial melleolides. |
2011 |
J. Biol. Chem. |
pmid:21148562
|
Nakano C et al. |
Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus. |
2011 |
J. Biol. Chem. |
pmid:21693706
|
Khosravi-Far R et al. |
Ras (CXXX) and Rab (CC/CXC) prenylation signal sequences are unique and functionally distinct. |
1992 |
J. Biol. Chem. |
pmid:1332953
|
Qin N et al. |
In vitro isoprenylation and membrane association of mouse rod photoreceptor cGMP phosphodiesterase alpha and beta subunits expressed in bacteria. |
1992 |
J. Biol. Chem. |
pmid:1314827
|
Garza RM et al. |
Geranylgeranyl pyrophosphate is a potent regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA reductase degradation in yeast. |
2009 |
J. Biol. Chem. |
pmid:19776008
|
Bradfute DL and Simoni RD |
Non-sterol compounds that regulate cholesterogenesis. Analogues of farnesyl pyrophosphate reduce 3-hydroxy-3-methylglutaryl-coenzyme A reductase levels. |
1994 |
J. Biol. Chem. |
pmid:8120018
|
Oh DY et al. |
Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92. |
2008 |
J. Biol. Chem. |
pmid:18499677
|
Biardi L and Krisans SK |
Compartmentalization of cholesterol biosynthesis. Conversion of mevalonate to farnesyl diphosphate occurs in the peroxisomes. |
1996 |
J. Biol. Chem. |
pmid:8576183
|
Otto JC and Casey PJ |
The hepatitis delta virus large antigen is farnesylated both in vitro and in animal cells. |
1996 |
J. Biol. Chem. |
pmid:8617711
|
Bang S et al. |
Farnesyl pyrophosphate is a novel pain-producing molecule via specific activation of TRPV3. |
2010 |
J. Biol. Chem. |
pmid:20395302
|
Zhao B et al. |
Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site. |
2009 |
J. Biol. Chem. |
pmid:19858213
|
Wiedłocha A et al. |
Translocation of cytosol of exogenous, CAAX-tagged acidic fibroblast growth factor. |
1995 |
J. Biol. Chem. |
pmid:8530506
|
Light DR and Dennis MS |
Purification of a prenyltransferase that elongates cis-polyisoprene rubber from the latex of Hevea brasiliensis. |
1989 |
J. Biol. Chem. |
pmid:2808388
|
Light DR et al. |
Rubber elongation by farnesyl pyrophosphate synthases involves a novel switch in enzyme stereospecificity. |
1989 |
J. Biol. Chem. |
pmid:2808389
|
Miriyala S et al. |
Functional characterization of the atypical integral membrane lipid phosphatase PDP1/PPAPDC2 identifies a pathway for interconversion of isoprenols and isoprenoid phosphates in mammalian cells. |
2010 |
J. Biol. Chem. |
pmid:20110354
|
McGeady P et al. |
The farnesyl group of H-Ras facilitates the activation of a soluble upstream activator of mitogen-activated protein kinase. |
1995 |
J. Biol. Chem. |
pmid:7592846
|
Leichner GS et al. |
Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein. |
2011 |
J. Biol. Chem. |
pmid:21778231
|
Potter D and Miziorko HM |
Identification of catalytic residues in human mevalonate kinase. |
1997 |
J. Biol. Chem. |
pmid:9325256
|
Scholten JD et al. |
Synergy between anions and farnesyldiphosphate competitive inhibitors of farnesyl:protein transferase. |
1997 |
J. Biol. Chem. |
pmid:9218438
|
Kaneko R et al. |
Survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor-induced apoptosis in cancer. |
2007 |
J. Biol. Chem. |
pmid:17472962
|
Correll CC et al. |
Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. |
1994 |
J. Biol. Chem. |
pmid:8021239
|
Tschantz WR et al. |
Substrate binding is required for release of product from mammalian protein farnesyltransferase. |
1997 |
J. Biol. Chem. |
pmid:9092540
|
Schulbach MC et al. |
Identification of a short (C15) chain Z-isoprenyl diphosphate synthase and a homologous long (C50) chain isoprenyl diphosphate synthase in Mycobacterium tuberculosis. |
2000 |
J. Biol. Chem. |
pmid:10816587
|
Laufs U and Liao JK |
Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. |
1998 |
J. Biol. Chem. |
pmid:9727051
|
Hartman HL et al. |
Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium. |
2004 |
J. Biol. Chem. |
pmid:15131129
|
Khan SG et al. |
A rapid and convenient filter-binding assay for ras p21 processing enzyme farnesyltransferase. |
1995 |
J. Biochem. Biophys. Methods |
pmid:7494090
|
Saito Y and Ogura K |
Biosynthesis of menaquinones. Enzymatic prenylation of 1,4-dihydroxy-2-naphthoate by Micrococcus luteus membrane fractions. |
1981 |
J. Biochem. |
pmid:7275947
|
Fujisaki S et al. |
Biosynthesis of isoprenoids in intact cells of Escherichia coli. |
1986 |
J. Biochem. |
pmid:3519600
|